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Filtered Search Results
Medchemexpress LLC Ulipristal | 159811-51-5 | ≥98.0% | 433.58 | 50 MG
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Ulipristal is a selective progesterone receptor modulator (SPRM) that binds to the progesterone receptor, inhibiting PR-mediated gene expression and interfering with progesterone activity in the reproductive system.
- Selective progesterone receptor modulator (SPRM)
- Binds to the progesterone receptor
- Inhibits PR-mediated gene expression
- Interferes with progesterone activity in the reproductive system
- May suppress the growth of uterine leiomyomatosis
- Can be used as emergency contraception by inhibiting or delaying ovulation and affecting endometrial tissue
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Medchemexpress LLC HY-101865 5mg Medchemexpress, KKL-10 CAS:952849-76-2 Purity:>98%
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Medchemexpress, HY-101865 5mg KKL-10 CAS:952849-76-2 KKL-10 is a small-molecule ribosome rescue inhibitor with broad-spectrum antimicrobial activity against bacteria. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15667 10mg Medchemexpress, P005091 CAS:882257-11-6 Purity:>98%
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Medchemexpress, HY-15667 10mg P005091 CAS:882257-11-6 P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1629138-41-5 | Medchem Express | SRI-011381 | 5mg | 686239993 | HY-100347 | 329.488 | C20H31N3O
Medchem Express | DO-264 | 5mg | 475641541 | HY-114157 | 2301866-59-9 | 558.400 | C23H20Cl2F3N5O2S
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eMolecules 30045-16-0 | Medchem Express | Dehydrocorydaline | 5mg | 446275264 | HY-N0674 | MFCD00887635 | 366.436 | C22H24NO4
Ambeed | 2-(Dicyclohexylphosphino)-1-phenyl-1H-indole | 1g | 771331413 | A701958 | 740815-36-5 | MFCD06798303 | 389.523 | C26H32NP
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Medchemexpress LLC HY-B0510 500mg , Trimethoprim CAS:738-70-5 Purity:>98%
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HY-B0510 500mg Trimethoprim CAS: 738-70-5 Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Chlortetracycline Hydrochloride, 100 Grams
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Chlortetracycline Hydrochloride is a tetracycline antibiotic. Chlortetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. The interference disrupts the translation process and inhibits bacterial growth.
This antibiotic offers a broad spectrum of antibacterial activity against both Gram-positive and Gram-negative bacteria. It also forms complexes with calcium, magnesium, aluminum, and iron, leading to reduced absorption.
Additionally, it is useful to study bacterial susceptibility patterns or as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic.
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Alkali Scientific Erythromycin, 10 G
Erythromycin is a broad-spectrum macrolide antibiotic supplied as a high-quality powder for laboratory and research use. It is active primarily against Gram-positive bacteria and certain Gram-negative organisms by inhibiting protein synthesis through binding to the bacterial ribosome. This mechanism prevents bacterial growth and replication, making it useful for antimicrobial susceptibility testing and microbiological studies. Erythromycin is commonly used in culture media to selectively inhibit unwanted bacteria and support targeted microbial growth. It is widely applied in microbiology, pharmaceutical research, and biochemical laboratories where controlled antimicrobial activity is required for experimental accuracy.
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eMolecules 225120-65-0 | Medchem Express | Cathepsin inhibitor 1 | 5mg | 713705301 | HY-100231 | MFCD23704186 | 401.9 | C20H24ClN5O2
Pharmablock | 1H-indol-4-amine | 25mg | 779715863 | PBLJ2099 | 5192-23-4 | MFCD01076559 | 132.166 | C8H8N2
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Apexbio Technology LLC Letrozole 112809-51-5 100mg
Letrozole (CAS 112809-51-5) is a nonsteroidal reversible type II aromatase inhibitor that exhibits an IC50 of 11 5 nM It interacts with aromatase by coordinating to the heme iron within the cytochrome P450 complex via its 1 2 4-triazole moiety and a heterocyclic pyrrole component thereby inhibiting estrogen biosynthesis without affecting adrenal corticosteroids In research models letrozole has been shown to reduce synaptic and axonal growth in the spinal cord downregulate estrogen receptor expression and impact synaptic proteins such as GAP-43 with implications for neuroendocrine regulation and memory It is frequently used to investigate estrogen signaling and feedback mechanisms in reproductive and neurobiological studies
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eMolecules 78110-38-0 | Aztreonam | Chem-Impex435.430 | C13H17N5O8S2 | 96.000 | CC1C(NC(=O)C(=NOC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O | 25g | 112543146
Aztreonam | Chem-Impex | 78110-38-0435.430 | C13H17N5O8S2 | 96.000 | CC1C(NC(=O)C(=NOC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O | 25g | 112543146
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Medchemexpress LLC IRAK4-IN-4 25mg | 1850276-58-2 | 25 MG
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IRAK4-IN-4 is a research-grade small-molecule inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with demonstrated potency in enzymatic assays.
- Potent IRAK4 inhibitor (IC50 = 2.8 nM).
- Inhibits cyclic GMP-AMP synthase (cGAS) with IC50 = 2.1 nM.
- High purity (99.55%).
- Molecular formula C22H16N2O2; molecular weight 340.37.
- Light yellow to yellow solid supplied in milligram quantities.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years) or -20°C (1 year).
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Medchemexpress LLC Sting agonist-7 | 2767442-46-4 | 97.2% | C17H12N4O4 | 10MG
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STING agonist-7 is a non-nucleotide agonist of the stimulator of interferon genes (STING) pathway used in research to probe STING-mediated immunology and inflammation. It binds selectively to mouse STING but not human STING and has limited cell membrane permeability. The compound is supplied at high purity and is DMSO-soluble for experimental applications.
- Non-nucleotide STING agonist suitable for pathway studies.
- Selective binding to mouse STING with minimal activity on human STING.
- Poor cell membrane permeability, relevant for assay design.
- High purity (~97.2%) for reproducible results.
- Soluble in DMSO (62.5 mg/mL); ultrasonic aid recommended.
- Storage: 4°C protected from light; in solvent store at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Pptn hydrochloride | 1992047-65-0 | 99.89% | 511.96 | 10 MG
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PPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. It shows no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. It also exhibits anti-inflammatory and anti-immune activity.
- Potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist
- Exhibits no agonist or antagonist effect at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors
- Inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM (in the presence of 10 μM UDP-glucose) and ~4 nM (in the presence of 100 μM)
- Significantly decreases the ratios of p-ERK1/2 to ERK1/2 and p-p38 to p38 at 10 μM
- Anti-inflammatory activity
- Anti-immune activity
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Medchemexpress LLC HDAC-IN-4 | 1252003-13-6 | 50 MG
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HDAC-IN-4 is a selective inhibitor targeting both HDAC6 and HDAC10, exhibiting pIC50 values of 7.2 and 6.8 in BRET assays, respectively. This compound has demonstrated antitumoral activity.
- Selective HDAC6 and HDAC10 inhibitor
- Exhibits antitumoral activity
- Used in BRET assays
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