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Filtered Search Results
Medchemexpress LLC Sirolimus-13C,d3 | 00-00-0 | MFCD00867594 | 97.1% | 918.18 g/mol | C5013CH76D3NO13 | 1 MG
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Rapamycin-13C,d3 is a stable isotope-labeled form of rapamycin supplied as a high-purity reference standard for use as an internal standard or tracer in quantitative bioanalytical methods such as LC-MS and GC-MS. It preserves the chemical identity of rapamycin while incorporating 13C and deuterium labels to aid accurate quantitation and metabolic studies.
- Stable isotope-labeled (13C and d3) for accurate quantitation.
- Suitable as an internal standard for LC-MS and GC-MS workflows.
- High purity (97.05%) supports reliable analytical performance.
- Available in small analytical pack sizes (500 μg, 1 mg, 5 mg, 10 mg).
- Storage recommendations: -20°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Mk-28 | 864388-65-8 | 99.88% | 396.44 | 100 MG
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MK-28 is a potent and selective PERK activator that demonstrates significant pharmacokinetic properties and high blood-brain barrier (BBB) penetration in mice. It has been shown to rescue cells from ER stress-induced apoptosis in vitro and improve systemic function and survival in R6/2 mice, an animal model for Huntington's disease. MK-28 also enhances motor and executive functions and delays the onset of death in R6/2 mice without causing toxicity.
- Potent and selective PERK activator
- Exhibits significant pharmacokinetic properties
- High blood-brain barrier (BBB) penetration in mice
- Rescues cells from ER stress-induced apoptosis in vitro
- Improves systemic function and survival in R6/2 mice
- Enhances motor and executive functions and delays death onset in R6/2 mice
- Activates EIF2AK4 (GCN2)
- Has little or no effect on EIF2AK1 (HRI) or EIF2AK2 (PKR)
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Medchemexpress LLC HY-103447 10mg Medchemexpress, Zearalenone CAS:17924-92-4 Purity:>98%
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Medchemexpress, HY-103447 10mg Zearalenone CAS:17924-92-4 Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-17565A 50mg , Bleomycin (hydrochloride) CAS:67763-87-5 Purity:>98%
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HY-17565A 50mg Bleomycin (hydrochloride) CAS: 67763-87-5 Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Anisomycin 22862-76-6 50mg
Anisomycin is an activator of c-Jun N-terminal kinase (JNK) a stress-activated protein kinase implicated in apoptotic signaling pathways regulating cell proliferation cell cycle progression and apoptosis It activates the JNK pathway at approximately 25 ng/ml concentration Experimental studies demonstrate anisomycin s capability to sensitize apoptosis-resistant cancer cell lines such as DU145 prostate carcinoma cells to Fas-mediated apoptosis as well as to induce apoptosis in leukemic HL-60 cells and primary mouse embryonic fibroblast cells by initiating JNK activation Anisomycin is thus widely utilized as a molecular tool in apoptosis-related research and insight into JNK-associated cell signaling
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Medchemexpress LLC Lumefantrine-d9 | 2477594-24-2 | 97.0% | 1 MG
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Lumefantrine-d9 is the deuterium-labeled version of Lumefantrine, an antimalarial drug. Lumefantrine is used in combination with Artemether, forming artemether-lumefantrine (AL), which serves as a first- and second-line antimalarial drug. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitation during drug development.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Apexbio Technology LLC Anidulafungin(Synonyms: Eraxis, Ecalta, LY303366, VER-002, Anidulafungin acetate, V-echinocandin, Vicuron echinocandin), 100mg, CAS: 166663-25-8.
Anidulafungin (CAS 166663-25-8) also known as LY-303366 is a semisynthetic derivative of echinocandin B exhibiting antifungal activity It acts by inhibiting fungal cell wall synthesis through interference with the enzyme -(1 3)-D-glucan synthase In vitro analyses demonstrate that Anidulafungin inhibits various Candida species including C albicans C glabrata C tropicalis and C parapsilosis (MIC90 0 08 0 32 0 32 5 12 g/ml respectively) as well as Aspergillus species (MIC90 0 02 g/ml) Lack of significant efficacy was shown against Cryptococcus neoformans and Blastomyces dermatitidis This compound is useful for research exploring antifungal resistance mechanisms and therapeutics
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eMolecules 80-77-3 | Chlormezanone | Combi-Blocks, Inc. | MFCD00143951 | 273.730 | C11H12ClNO3S | 98.000 | CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O | 1g | 589788920
Chlormezanone | Combi-Blocks, Inc. | 80-77-3 | MFCD00143951 | 273.730 | C11H12ClNO3S | 98.000 | CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O | 1g | 589788920
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Medchemexpress LLC HY-100975 50mg Medchemexpress, TB5 CAS:948841-07-4 Purity:>98%
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Medchemexpress, HY-100975 50mg TB5 CAS:948841-07-4 TB5 is a potent, selective and reversible inhibitor of hMAO-B with a Ki value of 0.11±0.01 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 547-32-0 | 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide, sodium salt | 100mg
Ambeed | 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide, sodium salt | 100mg | 490553268 | A314813 | 547-32-0 | 274.270 | C10H11N4NaO2S
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TARGETMOL CHEMICALS INC DORIPENEM 50MG
Also available in 5 mg 10 mg 25 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Doripenem is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens. purity: 99%
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Medchemexpress LLC HY-15608 100mg , MPTP (hydrochloride) CAS:23007-85-4 Purity:98%
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Medchemexpress, HY-15608 100mg MPTP (hydrochloride) CAS:23007-85-4 Formula:C12H16ClN Purity:98% MPTP (hydrochloride) is a prodrug to the neurotoxin MPP + which causes permanent symptoms of Parkinson's disease. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 117467-28-4 | Medchem Express | Cefditoren (Pivoxil) | 10mg | 446268452 | HY-17452A | MFCD00933166 | 620.71 | C25H28N6O7S3
Pharmablock | 4-chloro-2-fluoro-pyridine-3-carbaldehyde | 25mg | 784546848 | PBT4959 | 1232432-20-0 | MFCD15143389 | 159.540 | C6H3ClFNO
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Medchemexpress LLC Rapamycin (sirolimus) | 53123-88-9 | MFCD00867594 | 914.17 g·mol⁻¹ | C51H79NO13 | 100 MG
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Rapamycin (sirolimus) (GMP) is a GMP-grade macrolide that binds FKBP12 and inhibits mTOR, used in research to modulate cell growth, autophagy, and signaling through the PI3K/Akt/mTOR pathway. It is intended for in vitro and preclinical applications where GMP-like material and batch consistency are required.
- GMP-grade material suitable for research and preclinical use.
- Targets mTOR via FKBP12 binding for pathway inhibition.
- Molecular formula C51H79NO13 and molecular weight 914.17 g·mol⁻¹.
- Provided as a solid for formulation or experimental preparation.
- Useful for studies of cell proliferation, autophagy, and signaling modulation.
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Apexbio Technology LLC Azithromycin Dihydrate 117772-70-0 10mM (in 1mL DMSO)
Azithromycin Dihydrate (CAS 117772-70-0) is a macrolide antibiotic targeting the bacterial 50S ribosomal subunit It is designed to inhibit bacterial protein synthesis thereby disrupting bacterial growth and replication Azithromycin Dihydrate exerts its biological activity primarily through reversible binding to the 50S ribosomal subunit inhibiting protein synthesis In in vitro assays Azithromycin Dihydrate demonstrates inhibitory activity against susceptible bacterial strains with reported IC50 values typically in the micromolar range Based on these pharmacological properties Azithromycin Dihydrate holds research potential in investigating mechanisms of antibiotic resistance bacterial susceptibility and developing therapeutic strategies against bacterial infections
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