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Filtered Search Results
Medchemexpress LLC HY-107765 5mg Medchemexpress, LY2955303 CAS:1433497-19-8 Purity:>98%
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Medchemexpress, HY-107765 5mg LY2955303 CAS:1433497-19-8 LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Vancomycin hydrochloride from Streptomyces orientalis meets USP testing specifications | 1404-93-9 | 1G
Vancomycin hydrochloride from Streptomyces orientalis meets USP testing specifications | Mol Wt: 1485.71 | 1404-93-9 | 1G
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Medchemexpress LLC HZX-02-059 | 2240205-30-3 | 99.4% | 487.48 | 50 MG
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HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. Methuosis primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death. This compound also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and inhibits c-Myc and NF-κB transcription.
- Potent methuosis inducer
- Dual-target PIKfyve/tubulin inhibitor
- Anticancer activity
- Induces cell vacuolization
- Promotes apoptosis
- Downregulates the p53 pathway
- Inhibits PI3K/AKT phosphorylation
- Inhibits c-Myc and NF-κB transcription
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eMolecules 32502-62-8 | Medchem Express | 3-Methyltoxoflavin | 5mg | 446259918 | HY-111117 | MFCD00449892 | 207.193 | C8H9N5O2
Medchem Express | Garcinol | 1mg | 495799608 | HY-107569 | 78824-30-3 | MFCD03700761 | 602.812 | C38H50O6
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Medchemexpress LLC Carboxyamidotriazole Orotate | 187739-60-2 | 99.7% | 580.76 | 5 MG
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Carboxyamidotriazole Orotate is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. It functions as a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. This product demonstrates anti-tumor, anti-inflammatory, and antiangiogenic effects.
- Functions as a cytostatic inhibitor of nonvoltage-operated calcium channels.
- Inhibits calcium channel-mediated signaling pathways.
- Exhibits anti-tumor effects.
- Exhibits anti-inflammatory effects.
- Exhibits antiangiogenic effects.
- Inhibits cell proliferation of LAMA84R and K562R cell lines.
- Reduces phosphorylation of CrkL.
- Shows dose-dependent inhibition of total and phosphorylated Bcr-Abl levels.
- Displays antitumor activity on CML xenografts.
- Increased survival in animal models.
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Medchemexpress LLC HY-103361 5mg Medchemexpress, SB297006 CAS:58816-69-6 Purity:>98%
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Medchemexpress, HY-103361 5mg SB297006 CAS:58816-69-6 SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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AdipoGen Daptomycin
Chemical. CAS 103060-53-3. Formula C72H101N17O26. MW 1620.7. Daptomycin, a naturally occurring cyclic lipopeptide, is a calcium-dependent antibiotic. It exhibits potent bacteriocidal activity against most Gram-positive bacteria in vitro and in vivo, including antibiotic-resistant strains such as MRSA and VRE. Daptomycin disrupts the bacterial plasma membrane function, which results in membrane depolarization consequently leading to inhibition of protein, DNA and RNA synthesis, essential for cell division and cell wall synthesis.
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Chem-Impex International, Inc. Erythromycin | 114-07-8 | MFCD00084654 | 5G
Erythromycin, 114-07-8, MFCD00084654, 5G
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Chem-Impex International, Inc. Amoxicillin | 26787-78-0 | MFCD00072029 | 1G
Amoxicillin, 26787-78-0, MFCD00072029, 1G
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Chem-Impex International, Inc. Amoxicillin | 26787-78-0 | MFCD00072029 | 5G
Amoxicillin, 26787-78-0, MFCD00072029, 5G
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Chem-Impex International, Inc. Azlocillin sodium salt | 37091-65-9 | MFCD07793330 | 1G
Azlocillin sodium salt, 37091-65-9, MFCD07793330, 1G
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Apexbio Technology LLC Perphenazine 58-39-9 1g
Perphenazine (CAS 58-39-9) is a phenothiazine derivative that primarily acts as an antagonist at dopamine D receptors with dissociation constant (Ki) of 1 4 nM and also displays significant binding to histamine H (Ki 8 nM) A-adrenergic (Ki 10 nM) A- B- C-adrenergic and muscarinic M (Ki 1848 nM) receptors Its antagonism at D receptors underlies its ability to modulate dopaminergic neurotransmission while interaction with additional receptor subtypes may account for its effects on the central nervous system and antiemetic properties Perphenazine is widely utilized in research investigating mechanisms of antipsychotic activity dopaminergic regulation and drug-induced cell death pathways
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Cayman Chemical RoxIthromycIn 1g
A macrolide antibiotic; active against five strains EAch of Staphylococcus and Streptococcus (geometric mean MICs = 0.08 and 0.79 UG/ml, respectively), as well as several strains EAch of Corynebacterium, Haemophilus, and S. pneumoniae (MIC50s = 0.02, 0.01, and 2.5 UG/ml, respectively); protective against infection by strains of S. aureus, S. pyogenes, S. pneumoniae, or L. monocytogenes in mice (PD50s = 23-98 mg/kg)
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Medchemexpress LLC Di((Z)-non-2-en-1-yl) 8,8'-((((2-(dimethylamino)ethyl)thio)carbonyl)azanediyl)dioctanoate | 1777792-34-3 | 98.0% | C39H72N2O5S | 10MG
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ATX-002 is an ionizable cationic lipid intended for incorporation into lipid nanoparticles to enable delivery of RNA therapeutics. It is described in patent literature and provided by research suppliers with reported properties useful for formulation and preclinical studies.
- Designed for lipid nanoparticle encapsulation of RNA.
- Calculated pKa 8.68 and measured pKa 6.03, enabling pH-dependent ionization.
- Oil-phase material, light yellow to yellow in appearance.
- High purity suitable for preclinical research (reported 98.0%).
- Molecular formula C39H72N2O5S; exact mass ≈ 681.06.
- Used in siRNA and mRNA formulation studies with demonstrated in vivo activity in patent examples.
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Medchemexpress LLC Polygalasaponin V | 162857-65-0 | 5 MG
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Polygalasaponin V is a triterpenoid saponin isolated from the aerial parts of *Polygala japonica*. This compound has been studied for its potential expectorant, anti-inflammatory, antibacterial, and antidepressant properties, reflecting its traditional use in folk medicine.
- Isolated from *Polygala japonica*
- Molecular formula: C58H94O27
- Molecular weight: 1223.35
- Purity: 99.94%
- Appearance: White to off-white solid
- Classified as a triterpenoid saponin
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