Antibiotics
AG Scientific Inc Blasticidin S HCl Solution in HEPES Buffer 10 mg/mL, 1X1 mL
AG Scientific's Blasticidin S HCl solution is a sterile filterate solution. Blasticidin S HCl is an aminoacyl nucleoside antibiotic isolated from Streptomyces griseochromogenes. It functions by inhibiting peptide bond formation at the ribosome in both eukaryotic and prokaryotic cells. It blocks hydrolysis of peptidyl-tRNA due to the large ribosomal subunit's increased affinity for tRNA.Blasticidin S HCL has two deaminase genes: BSD from Aspergillus terreus and bsr from Bacillus cereus, where resistance is shown converting Blasticidin S HCl into a nontoxic deaminohydroxy derivative.Concentration: 10 mg/mL in HEPES buffer
Research Products International Corp NP-40 Lysis High Salt Buffer Solution, 250 Milliliters
1X buffer used for extracting proteins from cells.
Medchemexpress LLC N-(4-mesitylthiazol-2-yl)benzamide | 1001753-24-7 | 99.5% | 322.42 | C19H18N2OS | 25 MG
INH6 is a small-molecule Nek2/Hec1 inhibitor that inactivates Hec1/Nek2 function via protein degradation, leading to chromosome missegregation and cell death. It inhibits HeLa cell growth with an IC50 of 2.4 μM and produces mitotic defects and apoptosis in treated cells.
- Potent Nek2/Hec1 inhibition (IC50 2.4 μM).
- Inactivates Hec1/Nek2 through protein degradation, causing chromosome missegregation.
- Induces mitotic defects and apoptosis in cultured cells (~20% apoptotic cells at 72 h).
- Solid, white to off-white powder; soluble in DMSO (50 mg/mL) and in 10% DMSO/90% corn oil for animal dosing.
- Stable as powder at -20°C (3 years) and 4°C (2 years); in solvent stability varies by temperature.
Apexbio Technology LLC Perphenazine 58-39-9 1g
Perphenazine (CAS 58-39-9) is a phenothiazine derivative that primarily acts as an antagonist at dopamine D receptors with dissociation constant (Ki) of 1 4 nM and also displays significant binding to histamine H (Ki 8 nM) A-adrenergic (Ki 10 nM) A- B- C-adrenergic and muscarinic M (Ki 1848 nM) receptors Its antagonism at D receptors underlies its ability to modulate dopaminergic neurotransmission while interaction with additional receptor subtypes may account for its effects on the central nervous system and antiemetic properties Perphenazine is widely utilized in research investigating mechanisms of antipsychotic activity dopaminergic regulation and drug-induced cell death pathways
Research Products International Corp Blasticidin S Hydrochloride 10mg/ml Solution, 100 Milligrams
Blasticidin S HCl Solution 10 mg/mL is a sterile, DNase/RNase-free solution in HEPES buffer. It is a nucleoside antibiotic derived from Streptomyces griseochromogenes with high purity, commonly used in molecular biology, biotechnology, and gene editing applications such as CRISPR. It functions as a selection agent in cell culture by inhibiting protein synthesis in both prokaryotic and eukaryotic cells, allowing for the isolation of successfully modified cells. This product is ideal for creating stable cell lines and expressing recombinant proteins. Store at -20°C and avoid repeated freeze-thaw cycles.
Research Products International Corp Blasticidin S Hydrochloride 10mg/ml Solution, 200 Milligrams
Blasticidin S HCl Solution 10 mg/mL is a sterile, DNase/RNase-free solution in HEPES buffer. It is a nucleoside antibiotic derived from Streptomyces griseochromogenes with high purity, commonly used in molecular biology, biotechnology, and gene editing applications such as CRISPR. It functions as a selection agent in cell culture by inhibiting protein synthesis in both prokaryotic and eukaryotic cells, allowing for the isolation of successfully modified cells. This product is ideal for creating stable cell lines and expressing recombinant proteins. Store at -20°C and avoid repeated freeze-thaw cycles.
Research Products International Corp Blasticidin S HCl Solution 10mg/ml, 500 MG
Blasticidin S HCl Solution 10 mg/mL is a sterile, DNase/RNase-free solution in HEPES buffer. It is a nucleoside antibiotic derived from Streptomyces griseochromogenes with high purity, commonly used in molecular biology, biotechnology, and gene editing applications such as CRISPR. It functions as a selection agent in cell culture by inhibiting protein synthesis in both prokaryotic and eukaryotic cells, allowing for the isolation of successfully modified cells. This product is ideal for creating stable cell lines and expressing recombinant proteins. Store at -20°C and avoid repeated freeze-thaw cycles.
Research Products International Corp Blasticidin S Hydrochloride 10mg/ml Solution, 10 Milligrams
Blasticidin S HCl Solution 10 mg/mL is a sterile, DNase/RNase-free solution in HEPES buffer. It is a nucleoside antibiotic derived from Streptomyces griseochromogenes with high purity, commonly used in molecular biology, biotechnology, and gene editing applications such as CRISPR. It functions as a selection agent in cell culture by inhibiting protein synthesis in both prokaryotic and eukaryotic cells, allowing for the isolation of successfully modified cells. This product is ideal for creating stable cell lines and expressing recombinant proteins. Store at -20°C and avoid repeated freeze-thaw cycles.
Research Products International Corp Blasticidin S Hydrochloride 10mg/ml Solution, 20 Milligrams
Blasticidin S HCl Solution 10 mg/mL is a sterile, DNase/RNase-free solution in HEPES buffer. It is a nucleoside antibiotic derived from Streptomyces griseochromogenes with high purity, commonly used in molecular biology, biotechnology, and gene editing applications such as CRISPR. It functions as a selection agent in cell culture by inhibiting protein synthesis in both prokaryotic and eukaryotic cells, allowing for the isolation of successfully modified cells. This product is ideal for creating stable cell lines and expressing recombinant proteins. Store at -20°C and avoid repeated freeze-thaw cycles.
Medchemexpress LLC Nitd-2 | 1197896-79-9 | 99.4% | 433.48 g/mol | C23H19N3O4S | 5 MG
NITD-2 is a small-molecule inhibitor of dengue virus (DENV) RNA-dependent RNA polymerase (RdRp) that blocks RdRp-mediated RNA elongation. Supplied for research use, the compound is a solid with limited cell membrane permeability and documented physicochemical and storage properties.
- Inhibits DENV RdRp-mediated RNA elongation.
- Small-molecule inhibitor suitable for in vitro antiviral research.
- Limited cell membrane permeability may affect cellular uptake.
- High purity: 99.36% (analytical).
- Molecular formula C23H19N3O4S; molecular weight 433.48 g/mol.
- Soluble in DMSO (100 mg/mL); formulatable for in vivo use (≥2.5 mg/mL in 10% DMSO/corn oil).
- Powder stable at -20°C for up to 3 years; solvent stability guidelines available.
United States Biological Corporation Nourseothricin, (clonNAT), 1 Gram
Notch 1 is a transmembrane protein functioning in the development and determination of cell-fate (1). During maturation, the Notch molecule is cleaved by furin-like convertase at the extracellular domain (2). Upon binding to a ligand such as Delta1, or upon extracellular calcium depletion, the C-terminal Notch 1 fragment dissociates from its N-terminal counterpart and is further cleaved between Gly1743 and Val1744 (3,4). The resulting activated cytosolic fragment translocates to the nucleus and activates Notch-related transcription. Applications: Suitable for use in Western Blot, Immunoprecipitation, and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4C with gentle shaking, overnight. Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only.
Medchemexpress LLC Streptozotocin | 18883-66-4 | MFCD00006709 | ≥98% | 265.22 | 5 G
Streptozotocin (STZ) is an antibiotic commonly used in experimental animal models to induce diabetes. It enters B cells via the glucose transporter (GLUT2) and causes DNA alkylation, leading to the apoptosis of β cells. This compound is suitable for constructing models of both type 1 and type 2 diabetes.
- Induces cytotoxicity, oxidative stress, and mitochondrial dysfunction in HepG2 cells.
- Specifically transported by GLUT2 in GLUT2-expressing cells.
- Highly water-soluble and often dissolved in cold acidic citric acid buffer (pH 4.0-4.7).
- Distributes widely throughout the body, including crossing the blood-brain barrier and placenta.
- Undergoes chemical modification in the liver, converting into an active form that causes DNA methylation and damages pancreatic β-cells.
Research Products International Corp Neomycin Sulfate 1 KG
Neomycin Sulfate is an antibiotic that is derived from the bacterium Streptomyces fradiae and belongs to the aminoglycoside class of antibiotics. It exhibits broad-spectrum activity against Gram-negative and some Gram-positive bacteria.
In molecular biology, Neomycin Sulfate is commonly used as a selective agent in genetic engineering experiments and cell culture applications. It is often included in growth media or buffers to prevent the growth of bacteria and ensure the purity of cell lines.
Neomycin Sulfate functions by inhibiting protein synthesis in bacteria, leading to cell death. .
WARNING! This product can expose you to Neomycin sulfate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Research Products International Corp Neomycin Sulfate, 500 G
Neomycin Sulfate is an antibiotic that is derived from the bacterium Streptomyces fradiae and belongs to the aminoglycoside class of antibiotics. It exhibits broad-spectrum activity against Gram-negative and some Gram-positive bacteria.
In molecular biology, Neomycin Sulfate is commonly used as a selective agent in genetic engineering experiments and cell culture applications. It is often included in growth media or buffers to prevent the growth of bacteria and ensure the purity of cell lines.
Neomycin Sulfate functions by inhibiting protein synthesis in bacteria, leading to cell death. Neomycin Sulfate is also employed in microbiology research.
WARNING! This product can expose you to Neomycin sulfate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
Research Products International Corp Neomycin Sulfate, 5 Grams
Neomycin Sulfate is an antibiotic that is derived from the bacterium Streptomyces fradiae and belongs to the aminoglycoside class of antibiotics. It exhibits broad-spectrum activity against Gram-negative and some Gram-positive bacteria.
In molecular biology, Neomycin Sulfate is commonly used as a selective agent in genetic engineering experiments and cell culture applications. It is often included in growth media or buffers to prevent the growth of bacteria and ensure the purity of cell lines.
Neomycin Sulfate functions by inhibiting protein synthesis in bacteria, leading to cell death. Neomycin Sulfate is also employed in microbiology research.
WARNING! This product can expose you to Neomycin sulfate, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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