General Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ GRPR-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ GRPR-NFAT-bla CHO-K1 cells contain the human Gastrin Releasing Peptide Receptor (GRPR) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ OPRD1-bla U2OS Cells
The Tango™ OPRD1 -bla U2OS cells contain the human Opioid Receptor Delta 1 (OPRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ SCTR-CRE-bla CHO-K1 Cells
GeneBLAzer™ SCTR-CRE-bla CHO-K1 cells contain the human Secretin Receptor (SCTR) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ PTGER1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ PTGER1-NFAT-bla CHO-K1 cells contain the human Prostaglandin E Receptor 1 (Subtype 1) (PTGER1), (Accession No. NM_000955.2) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ PTGIR-CRE-bla CHO-K1 Cells
GeneBLAzer™ PTGIR-CRE-bla CHO-K1 cells contain the human Prostaglandin I2 receptor (IP) (PTGIR), (Accession No. NM_000960.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ MCHR2-NFAT-bla CHO-K1 Cells
GeneBLAzer MCHR2-NFAT-bla CHO-K1 cells contain the human melanin-concentrating hormone receptor 2 (GPR145) stably integrated into the CellSensor NFAT-bla CHO-K1 parental cell line.
Thermo Scientific™ GeneBLAzer™ M4-Gqo5-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M4 Gqo5-NFAT-bla CHO-K1 cells contain the human Acetylcholine (muscarinic) subtype 4 receptor (M4) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ T-REx™-G2A-NFAT-bla FreeStyle™ 293F Cells
GeneBLAzer™ T-REx™ G2A-NFAT-bla Freestyle HEK 293F cells contain the human GPR132 (G2A), (Accession No. NP_037477) stably integrated into the CellSensor™ NFAT-bla Freestyle HEK 293F cell line.
Thermo Scientific™ GeneBLAzer™ LTB4R-Gα15-NFAT-bla CHO-K1 Cells
GeneBLAzer™ LTB4R-Gα15-NFAT-bla CHO-K1 cells contain the human Leukotriene B4 Receptor (LTB4R), stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ CCKBR-NFAT-bla HEK293T Cells
GeneBLAzer™ CCKBR-NFAT-bla HEK293T cells contain the human Cholecystokinin Receptor B (CCKBR) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ GeneBLAzer™ Gqo5-NFAT-bla FreeStyle™ 293F Cells
GeneBLAzer™ Gqo5-NFAT-bla FreeStyle™ 293F cells contain the chimeric G-protein Gqo5 stably integrated into the CellSensor™ NFAT-blaFreeStyle™ 293F cell line.
Thermo Scientific™ GeneBLAzer™ CRHR1-CRE-blaCHO-K1 Cells
GeneBLAzer™ CRHR1-CRE-bla CHO-K1 cells contain the human Corticotropin Releasing Factor Receptor 1 (CRHR1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ M1-NFAT-bla Jurkat Cells
GeneBLAzer™ M1-NFAT-bla Jurkat cells contain the human Acetylcholine (muscarinic) subtype 1 receptor (M1) stably integrated into the CellSensor™ NFAT-bla Jurkat cell line.
Thermo Scientific™ GeneBLAzer™ ADRB3-CRE-bla CHO-K1 Cells
GeneBLAzer™ ADRB3-CRE-bla CHO-K1 cells contain the human Adrenrgic Beta 3 Receptor (ADRB3) (Accession No. NM_000025.1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ LanthaScreen™ STAT3 GripTite™ Cell Line
The JAK/STAT3 signaling pathway is known to be activated by cytokines such as IL-6. In this pathway, binding of IL-6 to its cell-surface receptors results in the activation of JAKs, which in turn phosphoactivate STAT3 proteins at a specific tyrosine residue (Y705).