Sera
Cayman Chemical 2PhenthylamInhydrochLRI 100mg
A natural monoamine alkaloid that acts as neuromodulator in the central nervous system; stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes; intended for forensic and research applications
Rockland Immunochemicals HUMAN SERUM (Lyophilized) - D314-05
Human Serum is used as a component of bioassays, immunoassays or enzyme assays. Human Serum provides a broad spectrum of macromolecules, carrier proteins for lipoid substances and trace elements, attachment and spreading factors, low molecular weight nutrients, and hormones and growth factors that promote cell growth and health. Human serum is also available as a sterile preparation for use as a cell culture supplement.
Cayman Chemical TRx0237mesylate 50mg
An inhibitor of tau aggregation; inhibits tau-tau binding (IC50 = 238 µM) and tau aggregation in 3T6H cells expressing human tau (EC50 = 0.19 µM); increases hippocampal ACh and synaptophysin levels, as well as increases mitochondrial complex IV activity, decreases tau pathology, and reverses deficits in spatial learning in the L1 transgenic mouse model of Alzheimer’s disease
Cayman Chemical HexythIazox 100mg
An acaricide; induces toxicity in larvae of the two-spotted spider mite T. urticae and the European red mite P. ulmi (LC50s = 0.15-0.58 and 0.23-0.62 mg AI/L, respectively), as well as in the summer and winter eggs of P. ulmi (LC50s = 2.2 and 20 ppm, respectively); toxic to bluegill (L. macrochirus; LC50 = 3.2 mg/L) and D. magna (EC50 = 0.36 mg/L) but not rats (LD50 = >5,000 mg/kg)
Cayman Chemical PAMAM DendrImR G5 5 Caryl 50mg
A carboxylate-terminated PAMAM dendrimer; has been used as a drug delivery system in vitro; ~103.9 Å in diameter in water and has 192 surface groups; does not induce cytotoxicity or autophagy in A549 cells at 100 UG/ml; bimetallic nanoparticles of PAMAM G5.5 with gold and platinum scavenge DPPH radicals in a cell-free assay; complexes of PAMAM G5.5 with the active component of cisplatin are cytotoxic to A2780 ovarian cancer cells (IC50 = 1.48 µM)
Cayman Chemical MetEnkephalInamIDtrIfluor 50mg
A peptide opioid receptor agonist; binds to opioid receptors in rat cerebellum homogenates (IC50 = 0.2 µM); reduces the twitch height in electrically stimulated isolated guinea pig ileum and isolated mouse vas deferens; induces analgesia in the hot plate and tail-flick tests in rats at 300 UG/animal
Cayman Chemical Nacetyl2 3dehydro2Deoxyn 100mg
A bacterial neuraminidase inhibitor (Ki = 48 µM for the A. sialophilus enzyme)
Cayman Chemical EpInastInhydrochlorIde 50mg
A histamine H1 receptor antagonist (apparent Kis = 1.41 and 1.62 nM using guinea pig cerebellar and lung membranes, respectively) and mast cell stabilizer; inhibits IgE-induced histamine, TNF-α, and IL-10 secretion in human CBMCs at 0.1 μg/ml; inhibits histamine-induced cutaneous vascular permeability in rats and bronchoconstriction in anesthetized guinea pigs (ID50s = 5 and 0.1 mg/kg, respectively); inhibits dye leakage into the conjunctiva in a rat model of passive anaphylaxis reaction-induced vascular hyperpermeability of the conjunctiva (ID50 = 9.7 mg/kg, p.o.); topical administration reduces lid edema, tearing, and redness, as well as the number of neutrophils and eosinophils in the lid fornix, in a mouse model of atopic conjunctivitis
Cayman Chemical FludIoxonIl 100mg
A fungicide; inhibits the growth of B. cinerea isolates from strawberry and blackberry crops (EC50s = 0.06-0.38 mg/L); inhibits the growth of S. cerevisiae AF293 and C. albicans IFO1385; an ERα agonist (EC50 = 3.7 μM in a yeast reporter assay); induces expression of the oncogenic microRNA miR-21, inhibits estradiol-induced proliferation, and reduces cell motility of MCF-7 breast cancer cells in vitro
Cayman Chemical Esaxerenon 100mg
A non-steroidal mineralocorticoid receptor antagonist (IC50 = 9.4 nM); selective for mineralocorticoid receptors over glucocorticoid, androgen, and progesterone receptors (IC50s = >10,000 nM for all); increases the urinary ratio of sodium to potassium in bilateral adrenalectomized rats at 0.3, 1, or 3 mg/kg; decreases systolic blood pressure in DOCA-salt hypertensive rats at 3 mg/kg; reduces systolic blood pressure, urinary protein levels, blood levels of BNP, kidney and left ventricle weights, and glomerulosclerosis, as well as increases blood potassium levels, in Dahl salt-sensitive rats fed a high-salt diet at 2 mg/kg per day
Cayman Chemical AcetylDLcarnItInchLRIde 50mg
A racemic mixture of acetyl-D-carnitine and acetyl-L-carnitine; increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine at 1 mM; decreases the hind limb vasculature blood flow rate in rats; decreases the levels of palmitic acid and oleic acid in the cerebral cortex during the recovery period in a dog model of insulin-induced hypoglycemic brain injury
Cayman Chemical PerfluorotrIdecnoIc AcId 100mg
A perfluoroalkyl substance; embryo-larval exposure induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish at 0.1 and 0.3 mg/L, respectively; decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty at 10 mg/kg; maternal plasma levels during gestation are positively associated with the development of eczema in female, but not male, infants; liver levels are higher in cancerous human livers compared with non-cancerous human livers; has been found in marine mammals
Cayman Chemical GastrodIa elta Gastrodn 50mg
A phenolic glycoside with diverse biological activities; reduces Aβ42-induced cell death of rat hippocampal neurons and BV-2 mouse microglia; improves learning and memory in various transgenic mouse models of Alzheimer's disease; reduces motor deficits and loss of dopaminergic neurons in a rat model of Parkinson's disease; reduces seizure duration and intensity in a rat model of pentylenetetrazole-kindling chronic epileptic seizures from 50-200 mg/kg; increases social interaction and decreases marble burying and grooming behaviors, as well as restores inhibitory synaptic transmission and GAT1 and α5 subunit-containing GABAA expression in the basolateral amygdala in a mouse model of valproic acid-induced autistic-like phenotypes at 100 mg/kg; increases biomechanical bone strength in a rat model of dexamethasone-induced osteoporosis; inhibits ethanol-induced hepatocellular apoptosis and restores liver function in a rat model of alcoholic liver disease