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Anticoagulated guinea pig blood suitable for use in complement titration, adsorption procedures, testing for agglutinins/HA assays, and the preparation of stroma as particulate reagents.
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A glycine-conjugated form of ursodeoxycholic acid; has antioxidant effects in vitro in Barrett’s esophagus cells and primary cultured rat neurons; reduces the levels of inflammatory cytokines and prevents cell death induced by unconjugated bilirubin in an astroglial cell model of neonatal hyperbilirubinemia; decreases the severity of symptoms and increases the amount of A. muciniphila in a mouse model of colitis at 500 mg/kg per day
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γ-Linolenic acid is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. γ-Linolenic acid produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}
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A CPT1 inhibitor and an active metabolite of oxfenicine; inhibits CPT1 in isolated rat liver mitochondria from 200 to 1,000 µM; inhibits oleate oxidation in isolated rat hepatocytes
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A glycine-conjugated form of chenodeoxycholic acid; reduces formation of cholic acid in primary human hepatocytes at 100 µM; reduces the number LC3 puncta and is cytotoxic to L-02 hepatocytes at 50, 75, and 100 µM; induces apoptosis in isolated rat hepatocytes at 50 µM; fecal levels are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet
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A naturally occurring fatty acid methyl ester; has been found in the cuticular wax of P. abies needles; has been found in sediment samples from the Harney River in Florida and Lake Kivu in the East African rift valley
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γ-Linolenic acid is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. γ-Linolenic acid produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An ω-alkyne derivative of docosahexaenoic acid; can be joined with azide-containing molecules using click chemistry; can be used track fatty acid metabolism in cells via click chemistry linkage to fluorophores
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An esterified form of DHA; increases plasma and erythrocyte membrane DHA levels in rats without altering arachidonic acid levels when administered in the diet to at a dose equivalent to 8 mg/kg of DHA; reduces the number of reference memory errors in an eight-arm radial maze in 100-week old rats at 300 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A glycine-conjugated form of chenodeoxycholic acid; reduces formation of cholic acid in primary human hepatocytes at 100 µM; reduces the number LC3 puncta and is cytotoxic to L-02 hepatocytes at 50, 75, and 100 µM; induces apoptosis in isolated rat hepatocytes at 50 µM; fecal levels are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More