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Filtered Search Results
Meso Scale Discovery RPLEX Mouse HAVCR1/KIM1 ASYQP
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The R-PLEX Mouse Havcr1 (KIM-1) Assay by Meso Scale Diagnostics measures Havcr1 (KIM-1) in mouse serum plasma and cell culture supernatants It uses electrochemiluminescence (ECL) detection for high sensitivity a 5-log dynamic range and low sample volume The kit includes a 96-well plate with capture antibodies ECL-labeled detection antibodies and calibrator solutions for a standard curve The assay takes about 3 hours and is used to analyze Havcr1 as a biomarker of kidney toxicity and injury
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Biotium Cathepsin D (Tumor Marker)(CTSD/3276), Biotin conjugate, 0.1mg/mL
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blu
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Miltenyi Biotec, Inc. CD70 Antibody, anti-human, Vio Bright B515, REAfinity™
Identification and enumeration of CD70+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Sino Biological Anti-MEK2 Antibody, Rabbit Polyclonal 100 µL
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Mouse MEK2, and purified by antigen affinity chromatography.
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Genscript Corporation CD69/CLEC2C His Human
CLEC2C (CD69) is a membrane-bound type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes natural killer (NK) cells and platelets CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits
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Biotium Calprotectin / MRP14 / S100A9 / Calgranulin B(rMAC3781), CF740 conjugate, 0.1mg/mL
Calprotectin is a heteroduplex of Protein S100-A8/A9 (also called MRP-8/14, or Calgranulin A/B). This antibody recognizes the 14 kDa B component (Protein S100-A9) of the complex. Protein S100-A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Altered expression of this protein is associated with the disease cystic fibrosis. This antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Sino Biological Anti-ALIX/PDCD6IP Antibody, Rabbit Polyclonal 100 µL
Produced in rabbits immunized with E. coli-derived Human ALIX/PDCD6IP fragment, and purified by antigen affinity chromatography.
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Biotium Calprotectin / MRP14 / S100A9 / Calgranulin B(rMAC3781), CF405S conjugate, 0.1mg/mL
Calprotectin is a heteroduplex of Protein S100-A8/A9 (also called MRP-8/14, or Calgranulin A/B). This antibody recognizes the 14 kDa B component (Protein S100-A9) of the complex. Protein S100-A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Altered expression of this protein is associated with the disease cystic fibrosis. This antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Biotium Cytokeratin 5 (KRT5) (Basal, Myoepithelial & Mesothelial Cell Marker)(KRT5/3594), CF647 conjugate, 0.1mg/mL
This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue f
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Genscript Corporation RBP4 His Human
The properties of retinol binding protein is the transport carrier of vitamin A in the plasma Human-retinol binding protein is a single-chain polypeptide with a molecular weight of approximately 21000 and one binding site for retinol and other forms of vitamin A In addition compounds related to retinol such as retinal retinoic acid retinyl esters and geometric isomers of retinol and of retinal were evaluated for their ability to bind to this protein In plasma RBP4-retinol forms a complex with transthyretin (TTR) also known as thyroxine-binding protein and prealbumin Defects in RBP4 cause retinol-binding protein deficiency which affects night vision
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ABclonal Technology KD Validated TRIM25 Rabbit mAb
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family The TRIM motif includes three zinc-binding domains a RING a B-box type 1 and a B-box type 2 and a coiled-coil region The protein is an RNA binding protein functions as a ubiquitin E3 ligase and is involved in multiple cellular processes including regulation of antiviral innate immunity
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Sino Biological Anti-NCAM-1/CD56 Antibody, Rabbit Polyclonal 100 µL
Produced in rabbits immunized with purified, recombinant Human NCAM-1/CD56 (rh NCAM-1/CD56; Catalog#10673-H08H; NP_001070150.1; Met1-Pro603). NCAM-1/CD56 specific IgG was purified by Human NCAM-1/CD56 affinity chromatography.
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Biotium S100A9 + Calprotectin (S100A8/A9 Complex)(MAC3157R), CF647 conjugate, 0.1mg/mL
Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including
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American Research Products Inc Rat Pro opiomelanocortin POMC
Rat Pro-opiomelanocortin (POMC) ELISA KIT from CUSABIO Detection Range 7 8 pg/mL-500 pg/mL Sensitivity 1 95 pg/mL Sample serum plasma cell culture supernates tissue homogenates Method Sandwich
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ABclonal Technology AKR1C2 Rabbit pAb
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
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