Goat Secondary Antibodies
Cayman Chemical KEMPFPKYPVEP Peptide (bovine, ovine) (trifluoroacetate salt), Purity: ≥95%, 250 mg
A peptide fragment of β-casein; can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria; increases the levels of dopamine, norepinephrine, and homovanillic acid, but not serotonin, in the frontal cortex of mice at 2 mg/kg; improves spatial alternation retention in the Y-maze spatial alternation task and increases novel object exploration time in a novel object recognition test in a mouse model of scopolamine-induced amnesia at 2 mg/kg
Cayman Chemical Cholenic Acid, Purity: ≥98%, CAS: 5255-17-4, 250 mg
A bile acid; formed by 7α-hydroxylation of 27-hydroxycholesterol; precursor in the biosynthesis of chenodeoxycholic acid; levels are increased in patients with neonatal liver disease harboring mutations in CYP7A1, as well as in patients with intrahepatic and extrahepatic cholestasis
Cayman Chemical L-Homoserine lactone (hydrochloride), Purity: ≥95%, CAS: 2185-03-7, 250 mg
A synthetic intermediate; has been used in the synthesis of organoselenium chemistry intermediates and analogs of bacterial quorum sensing signaling molecules
Cayman Chemical BIBO-3304 (trifluoroacetate salt), Purity: ≥98%, CAS: 191868-14-1, 10 mg
An antagonist of NPY receptor Y1 (Kis = 0.38 and 0.72 nM, respectively); selective for Y1 over Y2, Y4, and Y5 receptors (Kis = >1,000 nM for all); inhibits NPY-induced increases in food intake in fasted rats when injected into the PVN of the hypothalamus at 30 µg/animal; inhibits NPY- or bilateral common carotid artery occlusion-induced pressor response in cats at 100 µg/kg
Cayman Chemical PodoplnInRabbItMoncLNal100uL
A saikosaponin with anti-inflammatory and analgesic activities reduces basal PGE2 production in isolated rat peritoneal macrophages at 100 Ug/ml decreases acetic acid-induced writhing in SART mice at 5 mg/kg per day
Cayman Chemical Bathophenanthroline, Purity: ≥98%, CAS: 1662-01-7, 10 g
A colorimetric reagent for the detection of iron; can be used to quantify iron concentrations by colorimetric detection at 535 nm
Cayman Chemical 3'-Amino-3'-deoxyguanosine-5'-O-triphosphate (sodium salt), Purity: ≥95%, 2.6 mg
An amine-modified nucleotide; terminates RNA strand synthesis catalyzed by RNA polymerase in E. coli; has been used in the synthesis of a non-hydrolyzable derivative of pppGpp
Cayman Chemical 4-(3,4-Difluorobenzo)curcumin, Purity: ≥95%, CAS: 1170354-22-9, 25 mg
A semisynthetic coumarin with antiparasitic and anticancer activities; reduces the number of Vero cells infected with T. gondii promastigotes and amastigotes (EC50s = 0.8 and 0.37 µM, respectively); enhances 5-fluorouracil- and oxaliplatin-induced inhibition of primary and secondary colonosphere formation by chemoresistant HCT116 cells at 4 and 8 µM
Cayman Chemical 1,2-Dipalmitoyl-3-trimethylammoniumpropane (chloride), Purity: ≥95%, CAS: 139984-36-4, 50 mg
A cationic lipid; has been used as a transfection reagent in vitro and in vivo and in the formation of liposomes and microbubbles; microbubbles containing DPTAP and encapsulating miR-145 reduce atherosclerotic plaque area by 48.04% using UTMD in ApoE-/- mice in a model of atherosclerosis induced by a high-fat diet
Cayman Chemical PAMAM Dendrimer G3.0 Amine (water solution), CAS: 153891-46-4, 1 g
An amine-terminated PAMAM dendrimer; ~36 Å in diameter; has 32 surface groups; cytotoxic to DU145 cells (IC50 = ~13.42 µM); toxic to zebrafish embryos, inducing mortality 72 hours post-fertilization at 0.2 µM; liposomes coated with PAMAM G3.0 and encapsulating berberine and chrysophanol reduce hydrogen peroxide-induced production of ROS in ARPE-19 cells and protect against retinal damage in a rat model of photooxidation-induced AMD
Cayman Chemical Nordeoxycholic Acid, Purity: ≥95%, CAS: 53608-86-9, 250 mg
A metabolite of norcholic acid and derivative of deoxycholic acid; hepatic levels are decreased in rats in a high-fat diet model of NAFLD; serum levels are lower in men compared with women; has commonly been used as an internal standard for the quantification of bile acids in various sample types by GC- and LC-MS
Cayman Chemical N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine, Purity: ≥98%, CAS: 67219-55-0, 250 mg
A building block; has been used in the synthesis of oligodeoxyribonucleotides
Cayman Chemical Bevantolol (hydrochloride), Purity: ≥98%, CAS: 42864-78-8, 250 mg
A β1-AR antagonist (Ki = 14.79 nM in rat cortical membranes); selective for β1- over β2-ARs (Ki = 588.84 nM), as well as α2-ARs up to 100 μM, but is an antagonist of α1-ARs (Ki = 125.89 nM); inhibits LVA-ICa in dissociated rat ventro-medial hypothalamic neurons (IC50 = 40 μM); inhibits norepinephrine-induced contraction of isolated rabbit thoracic aorta (pA2 = 4.77), isoprenaline-induced inotropic effects in isolated guinea pig right atria (pA2 = 7.74), and isoprenaline-induce relaxation of isolated guinea pig trachea (pA2 = 6.69); prevents immobilization stress-induced increases in systolic blood pressure in a rat model of stress-induced hypertension at 250 mg/kg per day