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Filtered Search Results
Cayman Chemical Taurohyocholic Acid (sodium salt), Purity: ≥95%, CAS: 117997-17-8, 25 mg
A taurine-conjugated form of hyocholic acid; inhibits precipitation of cholesterol crystals by stabilizing cholesterol in the liquid-crystalline phase; prevents cholestasis and cellular necrosis induced by taurolithocholic acid in isolated rat livers; levels are increased in the urine of patients with hepatitis B-induced cirrhosis
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Cayman Chemical Olsalazine (sodium salt), Purity: ≥98%, CAS: 6054-98-4, 5 g
A prodrug form of 5-ASA; increases ion transport in isolated rabbit distal ileum when applied to the luminal side (ED50 = 0.3 mM); stimulates fluid transport in rat jejunum (5 mM); improves stool consistency and decreases occult and gross bleeding as well as MPO activity and LTB4 levels in colon tissue in a mouse model of dextran sulfate-induced colitis (150 mg/kg for 8 days); inhibits bovine xanthine oxidase in vitro (IC50 = 3.4 mg/L); lowers serum uric acid levels in an oxonic acid-induced mouse model of hyperuricemia (20 mg/kg)
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Cayman Chemical Mepenzolate (bromide), Purity: ≥95%, CAS: 76-90-4, 500 mg
A muscarinic M2 and M3 receptor antagonist (Kis = 0.68 and 2.6 nM, respectively); has antispasmodic activity in cats and dogs when administered at a dose of 0.5 mg/kg; decreases airspace enlargement induced by elastase or cigarette smoke in a mouse model of COPD; reduces oxidative stress, decreases the expression of pro-inflammatory cytokines, and increases the expression of anti-inflammatory cytokines in a mouse model of diabetic wound healing
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Cayman Chemical Sulfadiazine, Purity: ≥98%, CAS: 68-35-9, 25 g
A sulfonamide antibiotic; inhibits recombinant P. carinii DHPS (IC50 = 0.19 μM); active against clinical isolates of M. tuberculosis (MIC90 = 10 mg/L) and of N. meningitidis (MICs = 5-2,000 mg/L); active against A. pleuropneumoniae, S. choleraesuis, S. typhimurium, P. multocida, S. equi, and S. suis (MIC90s = T. gondii infection when administered in combination with pyrimethamine at 40 mg/kg per day
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Cayman Chemical AsprosIn PolycLNal ANTIBDY
Immunogen: Human recombinant protein • Host: Rabbit • Species Reactivity: (+) Human asprosin • Applications: IP, WB
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Cayman Chemical Penicillin V (potassium salt), Purity: ≥98%, CAS: 132-98-9, 10 g
A β-lactam antibiotic; inhibits the growth of clinical isolates of Streptococci (MICs = 0.004-0.008 mg/l) and C. difficile (MICs = 1 to >256 mg/l); inhibits growth of S. aureus in vitro (MIC = 0.016 mg/l) and in vivo in a thigh model of infection in mice; inhibits the growth of S. pyogenes in mice following one or two dose therapy (CD50s = 0.207 and 0.031 mg, respectively); prevents experimental acute otitis media in rats when administered at 100 mg/kg per day (p.o.) prior to infection by pneumococci
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Cayman Chemical Ethyl Orsellinate, Purity: ≥95%, CAS: 2524-37-0, 500 mg
A lichen metabolite and a derivative of lecanoric acid; inhibits the proliferation of human Hep-2 larynx carcinoma, MCF-7 breast cancer, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s = 31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively); toxic to brine shrimp (LC50 = 495 µM)
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Cayman Chemical Diclofenac (diethylamine), Purity: ≥98%, CAS: 78213-16-8, 10 g
An NSAID and a COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 µM, for human COX-1 and COX-2, respectively); inhibits A23187-induced release of arachidonic acid in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 µM, respectively); inhibits carrageenan-induced paw edema in rats
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Cayman Chemical Quinapril (hydrochloride), Purity: ≥98%, CAS: 82586-55-8, 500 mg
A prodrug form of quinaprilat; reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats at 3 mg/kg; inhibits angiotensin I-induced pressor responses in normotensive rats and dogs; prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters
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Bioss Metapnuemovirus
Metapnuemovirus Primary Antibody Unconjugated Host Species Mouse Target Species Clonality Monoclonal Applications ELISA Concentration 100 g/ml Size 100 ug Storage Buffer PBS (pH 7 2) with 0 1% azide
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Cayman Chemical Pralidoxime (chloride), Purity: ≥95%, CAS: 51-15-0, 1 g
Reactivates AChE that has been deactivated by binding of organophosphates to its esteratic site; binds to the anionic site of AChE and displaces the phosphate from the esteratic site through formation of phosphate-pralidoxime conjugates; reactivates paraoxon- and diisopropyl fluorophosphate-inactivated human RBC AChE with IC50 shifts of 0.3 and 0.8 nM per μM of pralidoxime, respectively; at a concentration of 10 μM, reactivates human RBC AChE that has been inactivated by chlorpyrifos, diazinon, and malathion by 17, 61, and 36%, respectively; binds to sarin-bound hAChE (Kd = 25.72 μM) and inhibits sarin-induced AChE deactivation (IC50 = 1.21 mM) in hemoglobin-free erythrocyte ghosts
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Cayman Chemical Ethambutol (hydrochloride), Purity: ≥98%, CAS: 1070-11-7, 1 g
An antimycobacterial compound; inhibits the growth of M. tuberculosis in vitro at a concentration of 10 μg/ml; protective against M. smegmatis infections in rhesus monkeys (50, 30, and 0% fatalities at doses of 12.5, 25, and 50 mg/kg, respectively); clears M. smegmatis pulmonary infiltrates at a dose of 100 mg/kg
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Cayman Chemical Fenoprofen (calcium salt hydrate), Purity: ≥98%, CAS: 71720-56-4, 25 g
An NSAID; inhibits spontaneous and estradiol-stimulated PGF2α release in isolated rat uterine horns; reduces serum PGF2α levels in rats (10 mg/kg); reduces acetic acid-induced writhing and stretching as well as formalin-induced licking behaviors, indicating analgesic activity in mice; induces formation of gastric lesions in mice
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Cayman Chemical 5-Hydroxymethyl-2-furancarboxylic Acid, Purity: ≥98%, CAS: 6338-41-6, 1 g
A major metabolite of 5-hydroxymethyl-2-furfural; can be used as a building block in the enzymatic synthesis of macrocyclic oligoesters
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ABclonal Technology PE anti-4-Hydroxynonenal
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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4-hydroxy-2-nonenal (4-hydroxynonenal 4-HNE) is a highly reactive aldehyde generated by the exposure of polyunsaturated fatty acids to peroxides and reactive oxygen species (ROS) It non-enzymatically forms stable protein adducts with histidine lysine and cysteine side chains that have been used as biomarkers for oxidative damage in cells Conditions where 4-HNE immunoreactivity has been observed include include inflammation neurodegenerative diseases and ischemic damage to the heart and brain
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