Goat Secondary Antibodies
Cayman Chemical Dansyl Chloride, Purity: ≥95%, CAS: 605-65-2, 25 g
A reactive probe for derivatization of primary amines, including those on amino acids, peptides, and polyamines, for detection by HPLC; has been used for the derivatization of phenol-containing compounds, such as steroids, for detection by MS/MS; a fluorescent probe for proteins and enzymes with ex/em = 340/535 nm, respectively, in acetone
Cayman Chemical Cefalothin (sodium salt), Purity: ≥98%, CAS: 58-71-9, 5 g
A β-lactam cephalosporin antibiotic; inhibits the growth of various Gram-positive and Gram-negative bacteria, including several strains of S. pyogenes, S. aureus, C. tetani, N. gonorrhoeae, Salmonella, and Shigella (MICs = 0.1-0.2, 0.312-0.625, 0.078, 1.25, 1.56-6.25, and 3.12-12.5 μg/ml, respectively); binds to E. coli PBPs (IC50s = S. pyogenes, D. pneumoniae, and S. aureus
Cayman Chemical LysophosphatIdylInosItolpor1mg
A glycerophospholipid isolated from porcine liver with various fatty acyl groups at the sn-1 position and a hydroxy group in the sn-2 position; formed via PLA1 or PLA2 catabolism of phosphatidylinositol; induce exocytotic release of insulin by pancreatic islet cells and intracellular calcium mobilization in a variety of cells; increase ERK1/2, Akt, and p38 phosphorylation via GPR55 activation; accumulate in transformed cell lines
Cayman Chemical 4-Methylpentanoic Acid-d12, Purity: ≥99% deuterated forms (d1-d12), CAS: 116287-57-1, 250 mg
An internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS
ABclonal Technology 647 anti-h/m ITGA5/CD49e
The product of this gene belongs to the integrin alpha chain family Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit This subunit associates with the beta 1 subunit to form a fibronectin receptor This integrin may promote tumor invasion and higher expression of this gene may be correlated with shorter survival time in lung cancer patients Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes
ABclonal Technology 647 anti-Human CLEC12A/CD371
This gene encodes a member of the C-type lectin C-type lectin-like domain (CTL CTLD) superfamily Members of this family share a common protein fold and have diverse functions such as cell adhesion cell-cell signaling glycoprotein turnover and roles in inflammation and immune response The protein encoded by this gene is a negative regulator of granulocyte and monocyte function Several alternatively spliced transcript variants of this gene have been described but the full-length nature of some of these variants has not been determined This gene is closely linked to other CTL CTLD superfamily members in the natural killer gene complex region on chromosome 12p13
Cayman Chemical AP-237 (hydrochloride), Purity: ≥98%, CAS: 17730-82-4, 5 mg
An analytical reference standard categorized as an opioid; intended for research and forensic applications
Cayman Chemical Methylchloroisothiazolinone/Methylisothiazolinone Mixture, CAS: 55965-84-9, 100 mL
A mixture of isothiazolinone biocides; effective against Gram-positive and Gram-negative bacteria (MICs = 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively); can elicit contact sensitization
Cayman Chemical Dipeptide diaminobutyroyl benzylamide (hydrochloride), Purity: ≥98%, 250 mg
A biomimetic peptide and muscarinic acetylcholine receptor antagonist; blocks sodium uptake and induces muscle relaxation
Cayman Chemical Santonin, Purity: ≥98%, CAS: 481-06-1, 5 g
A sesquiterpenoid lactone; has been used as a building block in the synthesis of terpenoids; an anthelmintic that induces paralysis of A. lumbricoides
Cayman Chemical Triadimenol, Purity: ≥95% (mixture of isomers), CAS: 55219-65-3, 250 mg
A metabolite of triadimefon; induces cranial nerve and ganglia abnormalities in a rat post-implantation whole embryo culture model from 12.5-125 μM; induces embryotoxicity in rats and rabbits when administered orally at doses of 100 and 40 mg/kg respectively; induces embryonic mortality as well as decreases fertility and increases the number of female offspring in medaka fish (O. latipes) from 3-3,000 μg/L
Cayman Chemical Hematoporphyrin (hydrochloride), Purity: ≥90% (mixture of isomers), CAS: 17696-69-4, 250 mg
A photosensitizer; increases oxygen consumption and decreases the RCR in irradiated isolated rat liver mitochondria at 3 μM; It induces DNA breaks in cell-free assays at 6 μM; decreases the survival of irradiated HeLa cells at 12 μM; decreases growth of subcutaneous Yoshida AH-130 hepatoma tumors in rats when administered with radiation at 5 mg/kg
Cayman Chemical 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside, Purity: ≥98%, CAS: 37067-30-4, 500 mg
A fluorogenic substrate for β-hexosaminidases; is cleaved by β-hexosaminidases to release the fluorescent moiety 4-ΜU; ex = 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively; em = 445 to 455 nm, increasing as pH decreases; has been used to quantify β-hexosaminidase activity in serum or leukocytes from patients with GM2 gangliosidoses such as Tay-Sachs disease
Cayman Chemical Sulfadimethoxine, Purity: ≥98%, CAS: 122-11-2, 5 g
A sulfonamide antibiotic; inhibits recombinant P. carinii DHPS (IC50 = 25 nM) in a cell-free assay; active against S. aureus, S. pneumoniae, K. pneumoniae, and E. coli in a disc assay; active against C. spiroforme isolates from rabbits (MIC90 = 256 μg/ml) and certain M. bovoculi isolates from keratoconjunctivitis infections in cows (MIC50 = ≤256 μg/ml); efficacious S. pneumoniae, K. pneumoniae, and E. coli systemic infections in mice (CD50s = 79.7, 2.7, and 12.2 mg/kg, respectively); efficacious against H. capsulatum systemic fungal infections in mice (CD50 = 300 mg/kg)
Cayman Chemical Amygdalin, Purity: ≥98%, CAS: 29883-15-6, 25 g
A glycoside with diverse biological activities; induces cell cycle arrest at the G0/G1 phase, decreases cyclin A and Cdk2 levels, and inhibits cell growth in UMUC-3, RT112, and TCCSUP bladder cancer cells from 1.25-10 mg/ml; reduces the number of primary microtubules and microvessels in aortic rings isolated from rats with streptozotocin-induced diabetes at 3 mg/kg; reduces triglyceride, total cholesterol, and LDL levels and aortic sinus plaque area in an LDLR-/- mouse model of atherosclerosis; reduces production of TNF-α, IL-1β, and IL-6 as well as neutrophil and macrophage infiltration in BALF in a mouse model of LPS-induced acute lung injury