Goat Secondary Antibodies
Cayman Chemical Oxotremorine (sesquifumarate), Purity: ≥95%, CAS: 17360-35-9, 1 g
A muscarinic acetylcholine receptor agonist; binds to M1, M2, M3, and M4 mAChRs (Kis = 3.31, 9.33, 5.24, and 7.08 µM, respectively, for the human receptors); inhibits ACh release in rat cerebral cortical slices at 10 µM, an effect that can be reversed by atropine; induces tremors, salivation, and lacrimation in mice (ED50s = 0.11, 0.22, and 0.28 mg/kg); induces analgesia in the hot plate test in mice at 0.5 mg/kg; has been used to induce parkinsonian symptoms as a model of Parkinson's disease in mice
Cayman Chemical Maduramicin (ammonium salt), Purity: ≥95%, CAS: 84878-61-5, 250 mg
A polyether ionophore antibiotic; selectively binds to monovalent cations over divalent cations; active against Gram-positive bacteria (MICs = 0.9-125 µg/ml); reduces the viability of asexual and gametocyte P. falciparum parasites (EC50s = 1.3 and 14.8 nM, respectively); reduces P. berghei transmission in a mouse model of malaria at 4 and 8 mg/kg; reduces the severity of lesions and completely protects chicks against mortality in a model of E. tenella-induced coccidiosis at 5-10 ppm in the diet
Cayman Chemical Gitogenin, Purity: ≥98%, CAS: 511-96-6, 25 mg
A sapogenin with enzyme inhibitory and hormone-releasing activities; an inhibitor of UGT1A4 (IC50 = 0.69 µM); stimulates the release of growth hormone in primary rat pituitary cells at 20 µg/ml
Cayman Chemical p-Nitrophenyl β-D-Galactopyranoside, Purity: ≥98%, CAS: 3150-24-1, 10 g
A β-D-galactosidase chromogenic substrate; cleavage by β-D-galactosidase releases p-nitrophenol, which can be quantified by colorimetric detection at 420 nm as a measure of β-D-galactosidase activity
Cayman Chemical Pyrazinamide, Purity: ≥98%, CAS: 98-96-4, 10 g
An antimycobacterial compound; inhibits the growth of the human M. tuberculosis H37Rv strain (MIC = 150 μg/ml); increases survival in M. tuberculosis H37Rv-infected mice when administered orally (0.1% w/w in the diet) or subcutaneously (2.5 mg single injection) on the day of infection; inhibits the growth of M. lepraemurium in infected mice
Cayman Chemical cis-9,10-Epoxyoctadecanoic Acid, Purity: ≥95%, CAS: 24560-98-3, 10 mg
An epoxy fatty acid; has been found in the fungus P. carinii isolated from the lungs of rats in a model of P. carinii-induced pneumonia; plasma levels are decreased in patients with impaired liver function
Cayman Chemical Chlormezanone, Purity: ≥98%, CAS: 80-77-3, 500 mg
A muscle relaxant; induces paralysis in mice, guinea pigs, dogs, cats, and monkeys (EC50s = 133, <200, 100-250, 50, and 50 mg/kg, respectively); increases ataxia induced by pentobarbital and alcohol in mice; blocks the crossed extensor reflex of the spine without affecting the knee-jerk reflex in cats; induces head drop in rabbits
Revvity Health Sciences Inc Membrane Target Systems: Neuromedin U NMU1 (human) membrane preparation
Membrane Target Systems: Neuromedin U NMU1 (human) membrane preparation
Cayman Chemical 2-Nitroamino-2-imidazoline, Purity: ≥98%, CAS: 5465-96-3, 5 g
An intermediate in the synthesis of imidacloprid
Cayman Chemical 17-phenyl trinor Prostaglandin F2α dimethyl amide, Purity: ≥98%, CAS: 155205-90-6, 1 mg
An isomer of 17-phenyl trinor prostaglandin F2α ethyl amide
Cayman Chemical Stachyose (hydrate), Purity: ≥95%, CAS: 54261-98-2, 500 mg
An oligosaccharide and prebiotic; reduces the number of colonic lesions and serum TNF-α, IL-6, IL-10, and IL-17a levels, as well as increases gut levels of Akkermansia and Lactobacillus, in a rat model of DSS-induced colitis at 1 g/kg per day; decreases serum LPS, IL-6, and TNF-α levels and enriches Phascolarctobacterium, Bilophila, Oscillospira, and Turicibacter in the gut microbiota in a rat model of STZ- and high-fat diet-induced diabetes; enhances berberine-induced blood glucose control and improvements in insulin resistance, as well as decreases the fecal concentration of short-chain fatty acids, in the KKAγ mouse model of type 2 diabetes
Cayman Chemical p53 (cynomolgus monkey) Monoclonal Antibody (Clone 06), 1 mL
Immunogen: Recombinant cynomolgus monkey p53 • Host: Mouse• Species Reactivity: (+) Cynomolgus monkey • Cross Reactivity: (+) p53 • Applications: ELISA, WB
Revvity Health Sciences Inc PhenoVue Fura-2 AM, Calcium Indicator
PhenoVue Fura-2 AM, Calcium Indicator
Cayman Chemical Acetyl-β-methylcholine (chloride), Purity: ≥95%, CAS: 62-51-1, 25 g
A muscarinic agonist; decreases heart rate and blood pressure and increases the airway pressure time index in a dose-dependent manner in wild-type mice
Cayman Chemical Tetrachlorohydroquinone, Purity: ≥98%, CAS: 87-87-6, 10 g
A metabolite of pentachlorophenol; cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay); increases production of ROS, inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes; induces GSH depletion in mouse liver