Rabbit Secondary Antibodies
ABclonal Technology GAS2 Rabbit mAb
The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity Alternative splicing results in multiple transcript variants
ABclonal Technology UCHL5IP Rabbit mAb
This gene encodes a subunit of the augmin complex which regulates centrosome and mitotic spindle integrity and is necessary for the completion of cytokinesis The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37 Alternative splicing results in multiple transcript variants
American Research Products Inc Rabbit matriX metalloproteinas
Rabbit matriX metalloproteinase 2/Gelatinase A MMP-2 ELISA Kit from CUSABIO Detection Range 1 56 ng/mL-100 ng/mL Sensitivity 0 39 ng/mL Sample serum plasma tissue homogenates Method Sandwich
ABclonal Technology Decorin Rabbit mAb
This gene encodes a member of the small leucine-rich proteoglycan family of proteins Alternative splicing results in multiple transcript variants at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein This protein plays a role in collagen fibril assembly Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis This gene and the related gene biglycan are thought to be the result of a gene duplication Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients
Genscript Corporation MonoRab Rabbit Anti-scFv Cock
This product is specific for scFvs in different species (humanized mouse) and different orders (VH-linker-VL VL-linker-VH) It can also recognize various forms of scFv-based bispecific antibodies such as DART BITE TandAbs IgG(H)-scFv2 scFv-Fab-Fc etc
ABclonal Technology MTAP Rabbit mAb
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine The encoded enzyme is deficient in many cancers Multiple alternatively spliced transcript variants have been described for this gene
ABclonal Technology APC Rabbit anti-Mouse IgG2b
Enables antigen binding activity Acts upstream of or within phagocytosis positive regulation of immune response and positive regulation of phagocytosis Located in extracellular space Part of immunoglobulin complex circulating Orthologous to several human genes including IGHG1 (immunoglobulin heavy constant gamma 1 (G1m marker)) IGHG2 (immunoglobulin heavy constant gamma 2 (G2m marker)) and IGHG3 (immunoglobulin heavy constant gamma 3 (G3m marker))
Cayman Chemical CD5NTerm RabbIt Monclona 100uL
An inhibitor of B-RAF and C-RAF (IC50s 41 7 and 2 nM for wild-type B-RAF B-RAFV600E and wild-type C-RAF respectively) cytotoxic to B-RAFV600E-expressing A375 and SK-MEL-28 melanoma cells (IC50s 57 and 69 nM respectively) as well as COLO 205 and HCT116 colon and B-CPAP and CAL-62 thyroid cancer cells (IC50s 116 65 43 and 479 nM respectively) reduces tumor growth in A375 SK-MEL-28 SK-MEL-2 and SK-MEL-30 mouse xenograft models
Cayman Chemical GAPDHCTerm RabbIt Monclo 100uL
A cytosine derivative originally found to be an inhibitor of TET1 and TET2 (IC50s 33 and 73 UM respectively in cell-free assays) however it was found that the TET inhibitory activity was due to residual copper in the preparation copper-containing Bobcat 339 reduces DNA 5-hmC levels in HT22 hippocampal neurons at 10 UM but copper-free preparations do not reduce DNA 5-hmC levels in Hep3B cells at 50 UM
Cayman Chemical Anti-Histone H3 pan Rabbit Mo
Immunogen: Peptide corresponding to the C-terminus of human histone H3 • Host: Rabbit • Species Reactivity: Species independent • Cross Reactivity: (+) All histone H3 proteins independent of post-translational modifications (-) H2A, H2B, H4 • Applications: ELISA, ICC, multiplex-based assays, WB
Cayman Chemical CD5CTerm RabbIt Monclona 100uL
An inhibitor of SIK2 (IC50 50s 21.63 and 6.63 nM respectively) inhibits TNF-a secretion in RAW 264.7 cells (IC50 ~2.5 UM) and reduces phosphorylation of CRTC3 and HDAC4 in macrophages at 3 UM inhibits growth of 10 ovarian cancer cell lines (IC50s 0.8-2.6 UM) and increases sensitivity of eight of them to paclitaxel halts the cell cycle at the G2/M phase and induces apoptosis and tetraploidy in SKOV3 cells at 1 UM has an additive effect on reducing tumor growth when used in combination with paclitaxel in an ovarian cancer mouse xenograft model at 60 mg/kg per day
Cayman Chemical sPLA2Type IB RabbIt Moncl 1mL
Immunogen: Recombinant mouse sPLA2 (Type IB) • Host: Rabbit • Species Reactivity: (+) Mouse • Cross Reactivity: (+) sPLA2 (Type IB) • Applications: ELISA
ABclonal Technology FITC Rabbit anti-Human CD99
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration T-cell adhesion ganglioside GM1 and transmembrane protein transport and T-cell death by a caspase-independent pathway In addition the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation There is a related pseudogene located immediately adjacent to this locus
ABclonal Technology 594 Rabbit anti-Human CD1d
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells The human genome contains five CD1 family genes organized in a cluster on chromosome 1 The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail Two transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 594 Rabbit anti-Human CD161
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation Several genes of the C-type lectin superfamily including the rodent NKRP1 family of glycoproteins are expressed by NK cells and may be involved in the regulation of NK cell function The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins a transmembrane domain and a cytoplasmic domain The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus