UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. It exhibits little to no inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). This 4-oxazolidinone analogue acts as an anticancer agent by inhibiting cancer cell migration and invasion.
- Potent and selective urokinase-type plasminogen activator (uPA) inhibitor.
- IC50 of 0.2 μM for uPA.
- Minimal inhibition of tPA, plasmin, thrombin, and trypsin (IC50 > 100 μM).
- 4-oxazolidinone analogue.
- Acts as an anticancer agent.
- Inhibits cancer cell migration and invasion.
- For research use only.