Signal Transduction Reagents and Kits
Promega ROCK2 Kinase Enzyme System, 10microg
ROCK2 is a ubiquitously expressed serine/threonine kinase localized in the nucleus that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element.
Promega ADP-Glo™ Kinase Assay + p38δ Kinase Enzyme System
Recombinant full-length human p38 delta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. It is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines.
Promega RIPK2 Kinase Enzyme System, 10microg
RIPK2 (RIP2; RICK) is a death domain-containing protein kinase encoding a predicted 540-amino acid protein that contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain.
Promega CDK9/CyclinK Kinase Enzyme System, 10microg
Recombinant full-length human CDK9 and CyclinK proteins were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CDK9/CyclinK is a member of the cyclin-dependent protein kinase (CDK) family.
Promega ADP-Glo™ Kinase Assay + KHS1 Kinase Enzyme System
Recombinant full-length human KHS1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. KHS1 belongs to the ser/thr kinase family that has a STE20-like protein kinase domain, which stimulates the SAPK pathway.
Promega PASK Kinase Enzyme System, 10microg
Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.
Promega TAOK1 Kinase Enzyme System, 10microg
TAOK1 is a serine/threonine-protein kinase involved in regulation of the p38-containing stress-responsive MAP kinase pathway and extracellular signal-regulated protein kinase (ERK) kinases (MEKs).
Promega ADP-Glo™ Kinase Assay + PASK Kinase Enzyme System
Recombinant human PASK (981-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PASK or PAS domain containing serine/threonine kinase regulates the function of many intracellular signaling pathways involved in stress.
Promega ALK2 Kinase Enzyme System, 10microg
ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8.
Promega PRKG1 (PKG) Kinase Enzyme System, 10microg
Recombinant full-length human PRKG1 (PKG) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PRKG1 is a homodimer, with each monomer containing a regulatory cGMP-binding domain and a catalytic domain.
Promega LRRK2 Kinase Enzyme System, 10microg
LRRK2 or leucine-rich repeat kinase is a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain and a WD40 domain.
Promega ADP-Glo™ Kinase Assay + EIF2AK2 Kinase Enzyme System
Recombinant human EIF2AK2 (252-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EIF2AK2 (also known as double-stranded RNA-activated protein kinase) is shown to be involved in HIV/gp120-associated neurodegeneration.
Promega FLT3 (D835Y) Kinase Enzyme System, 10microg
Recombinant human FLT3 (D835Y) (571-993) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega MSK1 Kinase Enzyme System, 10microg
Recombinant full-length human MSK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega RET (Y791F) Kinase Enzyme System, 10microg
Recombinant human RET (Y791F) (amino acids 658-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.