Signal Transduction Reagents and Kits
Promega ADP-Glo™ Kinase Assay + RET (V804L) Kinase Enzyme System
Recombinant human RET (V804L) (amino acids 658-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega ADP-Glo™ Kinase Assay + MINK1 Kinase Enzyme System
Recombinant human MINK1 (1-320) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. MINK1 is a member of the germinal center family of kinases that are homologous to the Ste20 family and regulate a wide variety of cellular processes.
Promega PKC theta Kinase Enzyme System, 1mg
Recombinant full-length human PKC theta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Protein Kinase C theta (PKC theta) is an important component in the intracellular signaling cascade.
Promega RET (V804L) Kinase Enzyme System, 1mg
Recombinant human RET (V804L) (amino acids 658-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Promega JAK3 Kinase Enzyme System, 1mg
Recombinant human JAK3 (amino acids 781-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. JAK3 is a member of the JAK family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction.
Promega IRAK4 Kinase Enzyme System, 1mg
Recombinant full-length human IRAK4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Interleukin-1 receptor-associated kinase 4 is an important mediator in the signal transduction of Toll-like receptor and IL1R family members.
Promega ADP-Glo™ Kinase Assay + CAMK1γ Kinase Enzyme System
Full-length recombinant human CAMK1 gamma was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CAMK1 gamma (CLICK-III), a member of the CAMK family, is a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase.
Promega CDK9/CyclinK Kinase Enzyme System, 1mg
Recombinant full-length human CDK9 and CyclinK proteins were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CDK9/CyclinK is a member of the cyclin-dependent protein kinase (CDK) family.
Promega TAOK1 Kinase Enzyme System, 1mg
TAOK1 is a serine/threonine-protein kinase involved in regulation of the p38-containing stress-responsive MAP kinase pathway and extracellular signal-regulated protein kinase (ERK) kinases (MEKs).
Promega MARK1 Kinase Enzyme System, 1mg
Recombinant full-length human MARK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MARK1 is a member of the MARK family and is a serine/threonine-protein kinase that plays a key role in signal transduction.
Promega ADP-Glo™ Kinase Assay + MELK Kinase Enzyme System
Recombinant human MELK (1-340) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MELK or maternal embryonic leucine zipper kinase is a member of the Snf1/AMPK kinase family.
Promega PKC alpha Kinase Enzyme System, 1mg
Recombinant full-length human PKC alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC alpha is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases.
Promega PI:3PS Lipid Kinase Substrate, 0.5mg, 0.5ml
The lipid kinase substrates PIP2:3PS and PI:3PS are standalone substrates that are also part of the PI3K-Glo kinase profiling system.
Promega PAK3 Kinase Enzyme System, 1mg
Recombinant full-length mouse PAK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PAK3 is a member of the family of ser/thr p21-activating kinases that serve as targets for the small GTP-binding proteins Cdc42 and RAC.
Promega ADP-Glo™ Kinase Assay + p70S6Kb Kinase Enzyme System
Recombinant full-length human p70S6Kb was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. p70S6Kb is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases and is activated by mitogenic stimuli.