Signal Transduction Reagents and Kits
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Filtered Search Results
Abcam Ascorbic Acid Assay Kit
Ascorbic Acid Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Aat Bioquest Calbryte™ 520 AM | 2x50ug
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G protein"coupled receptors (GPCRs) and calcium channel targets. Followed by Fluo-3 being introduced in 1989, Fluo-4, Fluo-8 and Cal-520 were later developed with improved signal/background ratio, and became the widely used Ca2+ indicators for confocal microscopy, flow cytometry and high throughput screening applications. However, there are still a few severe problems with Fluo-4. For example, as for Fluo-3, in all most all the intracellular calcium assays with Fluo-4 AM, probenecid is required to prevent the cell-loaded Fluo-4 from leaking out of cells. The use of probenecid with Fluo-4-based calcium assays compromises the assay results since probenecid is well-documented to have a variety of complicated cellular effects. Calbryte™ 520, AM is a novel fluorescent and cell-permeable indicator for the measurement of intracellular calcium.
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BPS Bioscience Inc SBE Reporter HEK293 Cell Line, 2 vials of frozen cells, 2 x 10^6 cells in 1 ml of cell freezing medium, ~1.5 x 10^6 cells in 1 ml of 10% DMSO, >1 x 10^6 cells in 1 ml of freezing medium, adherent growth properties
SBE Reporter HEK293 Cell Line, 2 vials of frozen cells, 2 x 10^6 cells in 1 ml of cell freezing medium, ~1.5 x 10^6 cells in 1 ml of 10% DMSO, >1 x 10^6 cells in 1 ml of freezing medium, adherent growth properties
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Abcam NFkB p65 Transcription Factor Assay Kit
NFkB p65 Transcription Factor Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC Zolmitriptan 139264-17-8 100mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Zolmitriptan (CAS 139264-17-8) is a synthetic small molecule that functions as a selective agonist of serotonin 5-HT1B and 5-HT1D receptors By stimulating these receptors zolmitriptan modulates trigeminovascular neurotransmission leading to cranial vasoconstriction and inhibition of pro-inflammatory neuropeptide release These mechanisms underlie its ability to acutely alleviate migraine attacks both with and without aura as well as cluster headaches In biomedical research zolmitriptan serves as a tool compound for investigating serotonergic signaling pathways involved in nociception and vascular regulation associated with headache disorders
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Aat Bioquest Calbryte 520 AM (10x50 ug)
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G proteinquotcoupled receptors GPCRs and calcium channel targets. This catalog is for 10x50 ug.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Neogen Diagnostics K-Blue Luminescent Substrate, 200 ML, HRP, Microwell, Chemiluminescent
K-Blue Luminescent is a stabilized luminescent substrate for use with horseradish peroxidase immunoassays. It contains both luminol and hydrogen peroxide (H2O2) in a two-bottle format with long-term stability, high sensitivity, and excellent signal to noise. Maximal light emission occurs at 430 nm in the presence of peroxidase labeled conjugate. K-Blue Luminescent is compliant with Annex XVII for REACH and contains no hazardous substances at or above published reporting levels. Stable for a minimum of 18-months when stored at 2-8C.
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Echelon Biosciences Research Labs GERANYLGERANIOL 10 mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(E,E,E)-Geranylgeraniol is an intermediate in the biosynthetic pathway of vitamins E & K and is linked to proteins via post-translational modification. This item is non returnable
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AdipoGen SB202190 (1 mg)
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SB202190 (1 mg), Adipogen Life Sciences. Chemical. CAS: 152121-30-7. Formula: C20H14FN3O. MW: 331.3. Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Autophagic vacuole inducer
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Sigma Aldrich Fine Chemicals Biosciences PGO Enzyme Preparation 1 G capsules | 10CAP
PGO Enzyme Preparation 1 G capsules | 10CAP
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Thermo Scientific™ Picotamide, 98%
CAS: 32828-81-2 Molecular Formula: C21H10N4O3,C21H20N4O3 Molecular Weight (g/mol): 376.42 InChI Key: KYWCWBXGRWWINE-UHFFFAOYSA-N Synonym: 4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthalamide; IUPAC Name: 4-methoxy-N1,N3-bis[(pyridin-3-yl)methyl]benzene-1,3-dicarboxamide SMILES: COC1=CC=C(C=C1C(=O)NCC1=CC=CN=C1)C(=O)NCC1=CC=CN=C1
| CAS | 32828-81-2 |
|---|---|
| Molecular Weight (g/mol) | 376.42 |
| SMILES | COC1=CC=C(C=C1C(=O)NCC1=CC=CN=C1)C(=O)NCC1=CC=CN=C1 |
| Synonym | 4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthalamide; |
| IUPAC Name | 4-methoxy-N1,N3-bis[(pyridin-3-yl)methyl]benzene-1,3-dicarboxamide |
| InChI Key | KYWCWBXGRWWINE-UHFFFAOYSA-N |
| Molecular Formula | C21H10N4O3,C21H20N4O3 |
| Assay | 97% |
|---|---|
| CAS | 574-17-4 |
| Product Type | Signal Transduction Reagent |
| Formula Weight | 189.17g/mol |
Thermo Scientific Chemicals C16 Ceramide, 98%
CAS: 24696-26-2 Molecular Formula: C34H67NO3,C34H67NO3 Synonym: D-erythro-N-Palmitoylsphingosine; N-Hexadecanoyl-D-erythro-sphingosine
| CAS | 24696-26-2 |
|---|---|
| Synonym | D-erythro-N-Palmitoylsphingosine; N-Hexadecanoyl-D-erythro-sphingosine |
| Molecular Formula | C34H67NO3,C34H67NO3 |
Thermo Scientific Chemicals TAPI-2
CAS: 187034-31-7 Molecular Formula: C19H37N5O5,C19H37N5O5 Molecular Weight (g/mol): 415.54 InChI Key: LMIQCBIEAHJAMZ-UHFFFAOYNA-N Synonym: TNF-β Protease Inhibitor-2; IUPAC Name: N-[1-({1-[(2-aminoethyl)carbamoyl]ethyl}carbamoyl)-2,2-dimethylpropyl]-N'-hydroxy-2-(2-methylpropyl)butanediamide SMILES: CC(C)CC(CC(=O)NO)C(=O)NC(C(=O)NC(C)C(=O)NCCN)C(C)(C)C
| CAS | 187034-31-7 |
|---|---|
| Molecular Weight (g/mol) | 415.54 |
| SMILES | CC(C)CC(CC(=O)NO)C(=O)NC(C(=O)NC(C)C(=O)NCCN)C(C)(C)C |
| Synonym | TNF-β Protease Inhibitor-2; |
| IUPAC Name | N-[1-({1-[(2-aminoethyl)carbamoyl]ethyl}carbamoyl)-2,2-dimethylpropyl]-N'-hydroxy-2-(2-methylpropyl)butanediamide |
| InChI Key | LMIQCBIEAHJAMZ-UHFFFAOYNA-N |
| Molecular Formula | C19H37N5O5,C19H37N5O5 |
Thermo Scientific™ Elastase Inhibitor II
A potent irreversible inhibitor of human neutrophil elastase
| Sensitivity | Moisture Sensitive |
|---|---|
| Content And Storage | -30°C to -10°C |
| Description | White |
| Form | Solid |
| Product Type | Signal Transduction Reagent |
| Solubility | Soluble in methanol or DMSO |
| Synonym | HNE Inhibitor; MeOSuc-AAPA-CMK |
| Molecular Formula | C20H31ClN4O7 |
| For Use With (Application) | A potent irreversible inhibitor of human neutrophil elastase |
| Formula Weight | 474.90g/mol |