Enzymes and Inhibitors
Sigma Aldrich Fine Chemicals Biosciences Hippuryl-Arg carboxypeptidase substrate | 744-46-7 | MFCD00055706 | 250MG
Hippuryl-Arg carboxypeptidase substrate | Purity: >=98% (TLC) | Mol Wt: 335.36 | 744-46-7 | MFCD00055706 | 250MG
Revvity Health Sciences Inc HTRF Biotin-APP-Eu cryptate (BACE1 substrate), 5000 Assay Points
HTRF Biotin-APP-Eu cryptate (BACE1 substrate), 5000 Assay Points
Medchemexpress LLC Bz-Phe-Val-Arg-AMC | 88899-22-3 | 99.8% | 681.78 g·mol⁻¹ | C37H43N7O6 | 10 MG
Bz-FVR-AMC is a fluorogenic peptide substrate used to monitor procathepsin and related protease activity. The substrate releases 7-amino-4-methylcoumarin (AMC) upon enzymatic cleavage and has an observed kcat/Km of 1,070 mM⁻¹·s⁻¹; at high concentrations it can inhibit the reaction. Typical handling: supplied as a solid and stored frozen to maintain stability.
- Releases the fluorescent AMC reporter upon enzymatic cleavage.
- Used to measure procathepsin and related protease activity in biochemical assays.
- Reported kcat/Km of 1,070 mM⁻¹·s⁻¹.
- High concentrations may inhibit protease activity.
- Supplied as a solid and stored at -20 °C to maintain stability.
- Reported purity about 99.8% and molecular weight 681.78 g·mol⁻¹.
Cayman Chemical Renin Fluorogenic Substrate
A probe for renin activity; consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other; can be used to quantify renin activity at ex/em = 340/485-510 nm, respectively