Modifying Enzyme Buffers
Thermo Scientific™ Pyrophosphatase, inorganic (0.1 U/μL)
Catalyze the hydrolysis of inorganic pyrophosphate to two orthophosphates.
Thermo Scientific™ Buffers for RNA Transctription and Post-Transcriptional Modifications
Thermo Scientific enzymes for in vitro transcription are designed for efficient and reliable RNA synthesis. These enzymes cover the entire synthesis workflow from template preparation to post-transcriptional modifications, ensuring optimal performance and high yields of synthesized RNA.
Thermo Scientific™ Agarase (0.5 U/μL)
Specifically digests the agarose polysaccharide core, which allows for gentle yet efficient recovery of DNA or RNA fragments from low melting point agarose.
Thermo Scientific™ Kinase buffer I (5X)
For cellular and molecular biology applications
Thermo Scientific™ Kinase buffer II (5X)
For cellular and molecular biology applications
Thermo Scientific™ Alkaline Phosphatase Buffer-1 (5X)
For cellular and molecular biology applications
AdipoGen VX-745
Chemical. CAS 209410-46-8. Formula C19H9Cl2F2N3OS. MW 436.3. VX-745 is a potent inhibitor of p38α MAPK IC50=10nM with 20-fold selectivity over p38β and 1000-fold selectivity over closely related kinases, ERK1, MK2 and JNK1-3. p38α is a member of the mitogen-activated protein kinase MAPK family of serine/threonine protein kinases and is widely expressed in endothelial, immune or inflammatory cells and plays a central role in the regulation of proinflammatory cytokine production including TNF-α, IL-1β and IL-6. VX-745 is an anti-inflammatory agent that blocks IL-1β and TNF-α release in whole blood in vitro with IC50 values of 150 and 180nM, respectively. VX-745 showed anti-inflammatory efficacy in an animal model of rheumatoid arthritis and recently anti-neuroinflammatory potential in prevention of early-stage Alzheimers diseases AD.
Sigma Aldrich Fine Chemicals Biosciences Pyruvate Kinase from rabbi
Pyruvate Kinase (PK) is a glycolysis enzyme and has four isozymes L R M1 and M2. The L isozyme is localized in gluconeogenic tissues particularly in the liver. Whereas the R and M1 are localized in the adult skeletal muscles heart brain and erythrocytes respectively. M2 is localized in the nucleus of the cells.
Medchemexpress LLC Multi-kinase inhibitor 1 | 778274-97-8 | 99.1% | 418.37 g·mol⁻¹ | C20H17F3N4O3 | 1 ML
Multi-kinase inhibitor 1 is a small-molecule multi-kinase inhibitor provided as a ready-to-use 10 mM solution in DMSO for laboratory research. It has molecular formula C20H17F3N4O3, a molecular weight of 418.37 g·mol⁻¹, and CAS number 778274-97-8. Intended for research use only.
- Ready-to-use 10 mM solution in DMSO.
- High purity (99.05%).
- Molecular weight 418.37 g·mol⁻¹.
- CAS 778274-97-8.
- Supplied as 1 mL vial for single-use experiments.
Alkali Scientific Proteinase K, 100 Mg
Proteinase K is a high-activity protease enzyme used primarily in DNA and RNA extraction procedures. This enzyme is highly effective in breaking down proteins, including histones, which helps release nucleic acids from cellular and nuclear structures. Proteinase K remains active under a wide range of conditions, making it ideal for use in DNA extractions that involve detergents or other chemical treatments. This reagent is provided in a 100 mg package, suitable for larger experiments or multiple applications. It is frequently used in research labs, particularly in protocols for DNA purification, proteinase inactivation, and enzymatic assays.