Custom Enzymes and Inhibitors
Biochain Institute Inc Placenta Ribonuclease Inhibitor, 5000 units/PK
BioChain offers the most used enzymes in molecular biology and biochemistry, such as DNase I, RNase A, with premium quality and at the most competitive price.
Cayman Chemical ResolvIn E2 25ug
An SPM; inhibits increases in inflammatory exudate neutrophil infiltration in a zymosan A-induced mouse model of peritonitis; hepatic levels are increased in mice fed normal chow, as well as in a mouse model of high-fat diet-induced NAFLD, by dietary supplementation with EPA; plasma levels are increased by dietary supplementation with fish oil containing ω-3 PUFAs in patients with chronic kidney disease or peripheral artery disease
Selleck Chemical LLC Perifosine (KRX-0401) 5mg 157716-52-4 NSC639966
Perifosine (KRX-0401, NSC639966) is a novel Akt inhibitor with IC50 of 4.7 ?M in MM.1S cells, targets pleckstrin homology domain of Akt. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC GSK690693 50mg 937174-76-0
GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Mc-val-cit-pab-indibulin | 2055896-95-0 | MFCD32201121 | 95.8% | 945.49 g/mol | C50H55ClN9O8+ | 50 MG
MC-Val-Cit-PAB-Indibulin is an antibody-drug conjugate (ADC) drug-linker conjugate in which the tubulin inhibitor indibulin is attached via a cleavable MC-Val-Cit-PAB linker. It is intended for research use in ADC development and preclinical studies.
- Provides an indibulin payload linked through a protease-cleavable Val-Cit spacer
- Offers a maleimidocaproyl (MC) reactive handle for thiol conjugation
- Suitable for antibody-drug conjugate synthesis and preclinical evaluation
- Reported purity suitable for research applications
- Available in multiple milligram-scale package sizes for development needs
Selleck Chemical LLC Oxaliplatin 200mg 61825-94-3 L-OHP
Oxaliplatin (L-OHP) is a DNA alkylating agent that activates autophagy. Oxaliplatin inhibits DNA synthesis by conforming DNA adducts in RT4, TCCSUP, A2780, HT-29, U-373MG, U-87MG, SK-MEL-2, and HT-144 cells. DMF is recommended for dissolution. Solutions are best fresh-prepared. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Sumatriptan succinate >=98% (HPLC), solid | 103628-48-4 | MFCD00902856 | 10MG
Sumatriptan succinate >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 413.49 | 103628-48-4 | MFCD00902856 | 10MG
Sigma Aldrich Fine Chemicals Biosciences 4-Quinolinol 98% | 611-36-9 | MFCD00006777 | 5G
4-Quinolinol 98% | Purity: 98% | Mol Wt: 145.16 | 611-36-9 | MFCD00006777 | 5G
Selleck Chemical LLC GSK690693 10mg 937174-76-0
GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Potent, selective, and ATP-competitive CK2 inhibitor 1009820-21-6. MFCD13184796
Potent, selective, and ATP-competitive CK2 inhibitor 1009820-21-6. MFCD13184796
Selleck Chemical LLC Pazopanib HCl S1035-10mg
Pazopanib HCl is a novel multi-target inhibitor of VEGFR1 VEGFR2 VEGFR3 PDGFR FGFR c-Kit and c-Fms with IC50 of 10 nM 30 nM 47 nM 84 nM 74 nM 140 nM and 146 nM in cell-free assays respectively Pazopanib induces autophagic Type II cell death
Apexbio Technology LLC Potent and selective Aurora A Kinase inhibitor 1028486-01-2. MFCD16621243
Potent and selective Aurora A Kinase inhibitor 1028486-01-2. MFCD16621243
Selleck Chemical LLC SB525334 10mg 356559-20-1
SB525334 is a potent and selective inhibitor of TGF? receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6. *For Research & Development use only. Product is not intended for drug, household, or human consumption.