Custom Enzymes and Inhibitors
Medchemexpress LLC HY-103409 10mg Medchemexpress, ABT-724 (trihydrochloride) CAS:587870-77-7 Purity:>98%
Medchemexpress, HY-103409 10mg ABT-724 (triHCl) CAS:587870-77-7 ABT-724 trihydrochloride is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-110155A 5mg Medchemexpress, (Rac)-LM11A-31 (dihydrochloride) CAS:1214672-15-7 Purity:>98%
Medchemexpress, HY-110155A 5mg (Rac)-LM11A-31 (diHCl) CAS:1214672-15-7 (Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103409 5mg Medchemexpress, ABT-724 (trihydrochloride) CAS:587870-77-7 Purity:>98%
Medchemexpress, HY-103409 5mg ABT-724 (triHCl) CAS:587870-77-7 ABT-724 trihydrochloride is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-107613 5mg Medchemexpress, R 59-022 CAS:93076-89-2 Purity:>98%
Medchemexpress, HY-107613 5mg R 59-022 CAS:93076-89-2 R 59-022 (DKGI-I) is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 is a 5-HTR antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[3][4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10656 5mg Medchemexpress, SB-657510 CAS:474960-44-6 Purity:>98%
Medchemexpress, HY-10656 5mg SB-657510 CAS:474960-44-6 SB-657510 is a selective urotensin II (UII) receptor (UT) antagonist. The Ki values are 61, 17, 30, 65 and 56 nM for human, monkey, cat, rat and mouse receptors, respectively. SB-657510 exerts anti-inflammatory effects by inhibiting UII-induced upregulation of inflammatory mediators such as adhesion molecules, cytokines, and tissue factor in human vascular endothelial cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Takinib | 1111556-37-6 | MFCD11822633 | 5mg
Takinib | Purity: ≥98% (HPLC) | MW:322.36 | 1111556-37-6 | MFCD11822633 | 5mg
Sigma Aldrich Fine Chemicals Biosciences 4-Quinolinol 98% | 611-36-9 | MFCD00006777 | 5G
4-Quinolinol 98% | Purity: 98% | Mol Wt: 145.16 | 611-36-9 | MFCD00006777 | 5G
Sigma Aldrich Fine Chemicals Biosciences 4-Quinolinol 98% | 611-36-9 | MFCD00006777 | 10G
4-Quinolinol 98% | Purity: 98% | Mol Wt: 145.16 | 611-36-9 | MFCD00006777 | 10G
Selleck Chemical LLC JNJ-38877605 50mg 943540-75-8
JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Adavosertib (MK-1775) 25mg 955365-80-7 AZD1775
Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC GDC-0879 25mg 905281-76-7 AR-00341677
GDC-0879 (AR-00341677) is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM in A375 and Colo205 cells with activity against c-Raf as well; no inhibition known to other protein kinases. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Abexinostat (PCI-24781) 50mg 783355-60-2 CRA-024781
Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.