Custom Peptides
Cayman Chemical PlntamajosIde 10mg
A phenylethanoid with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 11.8 µM); inhibits 5- and 15-LO (IC50s = 0.375 and 96 µM, respectively); decreases viability of TE-1 ESCC cells at 20-320 UG/ml, as well as inhibits LPS-induced EMT in Eca-109 and TE-1 cells and decreases phosphorylated NF-κB levels in TE-1 cells; inhibits arachidonic acid-induced mouse EAr edema at 3 mg/ear
Cayman Chemical ErythromycylamIn 10mg
A macrolide antibiotic; active against a variety of bacteria, including strains of S. pyogenes, S. pneumoniae, L. monocytogenes, and B. pertussis (MICs = 0.06-0.12, 0.06-0.12, 1-2, and 0.015-0.25 UG/ml, respectively); active against 28 clinical isolates of MAC complex isolated from patients with AIDS (MICs = 4-16 UG/ml); inhibits polylysine and polyproline synthesis in a cell-free assay
Cayman Chemical N N NTrIacetylchItotrIose 10mg
A triose oligosaccharide derived from chitin; scavenges reactive oxygen species and protects DNA from oxidative damage
Cayman Chemical 71 1HTetrazolylACTAmIdo 10mg
A potential impurity in commercial preparations of cefazolin
Cayman Chemical BocLRRAMCtrIfluoroACTAte 10mg
A fluorogenic substrate for trypsin-like activity of the 26S proteasome or 20S proteolytic core; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity; ex/em = 340-360/440-460 nm, respectively
Cayman Chemical 8 4bromophenyl1 3 5 7tet 10mg
An intermediate in the synthesis of BODIPY-containing dyes; has been used as a precursor in the synthesis of BODIPY-containing photosensitizer dyes with antibacterial activity
Cayman Chemical SImurosertIb 10mg
An inhibitor of Cdc7 kinase (IC50 = 0.26 nM); selective for Cdc7 over Cdk2 and ROCK1 (IC50s = 6,300 and 430 nM, respectively); inhibits phosphorylation of MCM2 in HeLa cells (IC50 = 17 nM); reduces proliferation of COLO 205 cells (EC50 = 81 nM); inhibits the growth of a wide variety of cancer cells (GI50s = 30.2->10,000 nM); reduces intratumor levels of phosphorylated MCM2 in COLO 205 and SW948 mouse xenograft models at 80 mg/kg and reduces tumor growth in the same models when administered at doses of 40 or 60 mg/kg twice per day
Cayman Chemical OctnoylCoenzyme AsodIum s 10mg
A medium-chain acyl CoA; levels increased in liver in patients with Reye’s syndrome and β-oxidation of octanoyl-CoA by MCADH is decreased in patients with MCD; inhibits citrate synthase and glutamate dehydrogenase
Cayman Chemical ATM4 4-acetoxy nalog 10mg
An analytical reference standard categorized as a potential impurity in the synthesis of heroin; has been found in seized heroin samples; intended for research and forensic applications
Cayman Chemical 5-EAPBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; increases conditioned place preference for the 5-EAPB-paired chamber and reinforcement in a self-administration test in rats; has been found in seized samples suspected of containing NPS; associated with fatality; intended for research and forensic applications
Cayman Chemical N-ButylfluoresceIn 10mg
Ex/em = 467/512 nm, respectively; has been used in the synthesis of butyl FLIP, a fluorogenic substrate of PI-PLC
Cayman Chemical 2 3DImethylethcathInonhyd 10mg
A disubstituted analog of ethcathinone; intended for forensic and research purposes
Cayman Chemical 5-fluoro ABICA 10mg
A homolog of 5-fluoro AB-PINACA that differs by having an indole group in place of the indazole group
Cayman Chemical EdaglItazon 10mg
A PPARγ agonist; activates PPARγ in a reporter assay using CV-1 cells expressing murine PPARγ2 from 0.1-1 μM; increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats at 1, 5, and 25 μM
Cayman Chemical MoexIprIlat 10mg
An ACE inhibitor and active metabolite of the prodrug moexipril (IC50 = 2.1 nM); prevents the estrone- or angiotensin II-stimulated proliferation of primary neonatal rat cardiac fibroblasts at 10 nM; reduces mean arterial blood pressure and increases the levels of atrial natriuretic peptide in ovariectomized mice at 50 mg/kg per day