Custom Peptides
Cayman Chemical ElaIdIc AcId-d17 10mg
An internal standard for the quantification of elaidic acid by GC- or LC-MS
Cayman Chemical HValProProOHtrIfluoroac 10mg
A peptide ACE inhibitor (IC50 = 9 µM); inhibits acetylcholine-induced NO production in HUVECs at 1 µM; induces vasorelaxation in precontracted isolated rat aortic rings; decreases systolic blood pressure in spontaneously hypertensive rats at 0.3 mg/kg; dietary administration reduces plasma levels of total cholesterol, HDL-cholesterol, and triglycerides, expression of Il6 and Il1b, and aortic arch intimal thickening and atherosclerotic plaque formation in ApoE-/- mice
Cayman Chemical EstrIol 16a DGlucuronIde 10mg
A metabolite of estriol; plasma levels have been used as biomarkers of placental estriol production during pregnancy
Cayman Chemical Gardenoside, Purity: ≥95%, CAS: 24512-62-7, 10 mg
An iridoid glycoside with anti-inflammatory and antinociceptive activities; decreases free fatty acid-induced accumulation of lipid droplets and increases in TNF-α, IL-6, and IL-1β levels in HepG2 cells at 10 and 20 µM; reduces increases in the expression of purinergic P2X3 and P2X7 receptors, as well as reverses decreases in mechanical withdrawal thresholds in a rat model of chronic constriction injury-induced neuropathic pain
Cayman Chemical NADPH (cyclohexyl ammonium salt), Purity: ≥95%, CAS: 100929-71-3, 10 mg
The reduced form of the electron acceptor NADP+ and acts as an electron donor in various biological reactions
Cayman Chemical Galactosylsphingosine (d18:1) (synthetic), Purity: ≥98%, CAS: 2238-90-6, 10 mg
A bioactive sphingolipid; potentiates LPS-induced production of inflammatory cytokines, decreases the mitochondrial membrane potential, and induces cell death in mouse astrocytes; induces demyelination of mouse cerebellar slices at 0.1 and 1 µM; inhibits PDGF-induced translocation of PKC to the cell surface and induces apoptosis in MO3.13 oligodendrocytes; inhibits PPARα-mediated gene transcription in C6 glial cells at 10 and 15 µM; levels are increased in postmortem brain from patients with Krabbe disease
Cayman Chemical Dimethoate-d6, Purity: ≥99% deuterated forms (d1-d6), CAS: 1219794-81-6, 10 mg
An internal standard for the quantification of dimethoate by GC- or LC-MS
Cayman Chemical TDFAtrIfluoroacetate salt 10mg
An inhibitor of JNK (IC50 280 nM) competitive for JNK1 binding with pepJIP1 (IC50 500 nM) selective for JNK over p38a mTOR and PI3Ka inhibits c-Jun phosphorylation induced by TNF-a (EC50 12 4 UM) restores insulin sensitivity in a mouse model of type 2 diabetes when administered at 25 mg/kg 30 minutes prior to insulin reduces human prostate strip contractions induced by phenylephrine or norepinephrine when applied at 30 UM and reduces phosphorylation of c-Jun a JNK substrate
Cayman Chemical Zanubrutinib, Purity: ≥98%, CAS: 1691249-45-2, 10 mg
A potent and covalent BTK inhibitor (IC50 = 0.3 nM); selective for BTK over a panel of 304 kinases at 1 μM; inhibits EGFR, Tec, Blk, BMX, HER4, and TXK (IC50s = 0.62-33 nM); inhibits phosphorylation of BTK at Y233 (IC50 = 1.8 nM) in Ramos cells; reduces viability of REC-1 cells (IC50 = 0.36 nM); reduces tumor volume in an OCI-LY10 DLBCL mouse xenograft model at 2.5 and 7.5 mg/kg
Cayman Chemical Grassofermata, Purity: ≥98%, CAS: 419547-11-8, 10 mg
An inhibitor of fatty acid transport; inhibits C1-BODIPY-C12 uptake in HepG2, Caco-2, C2C12, and INS-1E cells (IC50s = 8.1-10.6 μM); prevents palmitate-mediated lipid accumulation and cell death in HepG2 cells and primary hepatocytes; decreases absorption of 13C-oleate in mice at 300 mg/kg
Cayman Chemical 6-EAPB (hydrochloride), Purity: ≥98%, CAS: 1823318-37-1, 10 mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical 2,3-Dimethylmethcathinone (hydrochloride), Purity: ≥95%, CAS: 1797981-99-7, 10 mg
A potential designer drug that is structurally related to 4-MMC; intended for research and forensic applications
Cayman Chemical Carbamazepine 10,11-epoxide, Purity: ≥98%, CAS: 36507-30-9, 10 mg
An active metabolite of carbamazepine; has anticonvulsant activity against maximal electroshock-induced seizures in mice; has been found in wastewater effluent
Cayman Chemical 5-fluoro PB-22 6-hydroxyisoquinoline isomer, Purity: ≥98%, CAS: 2365471-44-7, 10 mg
Differs from 5-fluoro PB-22 by having the quinoline group replaced with an isoquinoline group attached at its six position; intended for forensic and research purposes