Custom Peptides
Cayman Chemical Temafloxacin 10MG
A fluoroquinolone antibiotic that inhibits DNA topoisomerase inhibitor; broad antimicrobial activity against gram-positive and gram-negative bacteria, such as S. pneumoniae, M. hominis, and anaerobic bacteria, including B. fragilis
Cayman Chemical DIphenIdInhydrochlorIde 10mg
An analytical reference standard standard categorized as a dissociative anesthetic; has been found in samples seized by law enforcement; has a high potential for abuse; intended for research and forensic applications
Cayman Chemical 9deoxy9methylen Prostagla 10mg
9-deoxy-9-methylene PGE2 is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2.{464}
BANGS LABORATORIES INC Bangs Quantum™ Alexa Fluor 647 MESF Kit, Fluorescence Standardization, 100 Tests
The Bangs Laboratories Quantum™ Alexa Fluor 647 MESF 5mL kit is essential for quantitative fluorescence cytometry. It standardizes fluorescence intensity units through a calibration curve correlating instrument values with MESF units. Its key benefits include accurate cellular expression analysis and evaluation of instrument performance, with microspheres labeled for environmental responsiveness.
Cayman Chemical CarboxyamIdotrIazole 10mg
An orally bioavailable, non-selective calcium channel blocker; blocks L- and T-type calcium channels in GH3 rat pituitary cancer cells (IC50s = 0.5 and 1.5 μg/ml, respectively); blocks carbachol- and A23187-stimulated calcium influx in CHO cells expressing human recombinant M5 receptors (IC50s = 935 and 359 nM, respectively); inhibits the growth of T. gondii in non-cancerous human fibroblasts and HeLa human cervical cancer cells (IC50 = 0.06 μg/ml for both); inhibits the growth of human FaDu and EVSCC17M squamous cell carcinoma cells (IC50s = 13 and 15 μM, respectively) and of HUVECs (IC50 = 1 μM); inhibits angiogenesis in a chicken chorioallantoic membrane assay in vivo at 20 μM
Cayman Chemical AbacavIrsulfate 10mg
A nucleoside analog and HIV-1 reverse transcriptase inhibitor (Ki = 2.1 µM for the wild-type enzyme); inhibits replication of a variety of HIV-1 and HIV-2 strains, including strains resistant to zidovudine or didanosine in HeLa cells stably expressing CD4 (IC50s = 5.8-21 µM); inhibits replication of eight HIV-1 clinical isolates in phytohemagglutinin-stimulated isolated human peripheral blood lymphocytes (mean IC50 = 0.26 µM); inhibits HBV DNA synthesis in HepG2 cells (IC50 = 7 µM) and is also active against human cytomegalovirus (CMV) strain AD169 and the Petaluma strain of FIV in plaque reduction assays (IC50s = 32 and 0.4 µM, respectively)
Cayman Chemical LY2365109hydrochlorIde 10mg
An inhibitor of GlyT1a (IC50 = 15.8 nM in BE2-C cells expressing the human transporter); selective for GlyT1a over GlyT2 (IC50 = >30 µM in RD cells expressing the human transporter); induces locomotor hyperactivity, impaired gait, compulsive walking, and labored breathing, as well as impairs the ability to stand, in rats at 10 mg/kg; prevents maximal electroshock-induced acute seizures in mice at 30 mg/kg and decreases seizure number in an electroshock-induced rat model of chronic epilepsy at 10 mg/kg
Cayman Chemical nuropeptIde EIratrIflu 10mg
An endogenous peptide fragment of rat prepro-MCH; expressed in both the central and peripheral nervous systems, localizes to the cytoplasm, and colocalizes with MCH in the CNS; reduces TRH release in mediobasal hypothalamus explants at 1 µM; increases serum levels of LH in male rats and in chronically ovariectomized female rats that received estradiol benzoate and progesterone in addition to NEI; induces excessive grooming behavior and increases locomotor activity in rats at 1 UG/animal; increases the amount of time spent in REM sleep in rats when injected intracerebroventricularly or into the vlPAG
Cayman Chemical 1 4-D-XylobIose 10mg
A disaccharide; a degradation product of hemicellulose; has been found in T. reesei endoxylanase-treated birch kraft pulp
Cayman Chemical QuercetIn-7-OD-Glucopyrno 10mg
A flavonoid; has antioxidant activity in a ORAC assay and decreases tert-butyl hydroperoxide-induced ROS in L-929 cells at 0.25 and 1 UG/ml; reduces protein levels of iNOS and COX-2 in LPS-stimulated RAW 264.7 cells at 15 and 30 UG/ml; decreases angiogenesis in isolated rat aortic rings and proliferation of HUVECs but has no effect on tube formation or chemotaxis of HUVECs at 100 µM
Cayman Chemical BrequInarsodIum salt 10mg
A DHODH inhibitor (IC50 = ~20 nM); selective for DHODH over a panel of greater than 400 kinases at 100 nM; induces differentiation of ER-HoxA9, U937, and THP-1 cells in vitro (EC50s = ~1 µM); induces differentiation of tumor cells and reduces tumor growth in a THP-1 mouse xenograft model at 15 mg/kg three times daily or 5 mg/kg per day; induces differentiation of bone marrow leukemic cells and increases survival In a retroviral transduction mouse model of HoxA9 + Meis1 AML
Cayman Chemical C17 SphngomyelInd18 117 0 10mg
A synthetic derivative of sphingomyelin; has been used as an internal standard for the quantification of sphingomyelin
Cayman Chemical RopIdoxurIdIn 10mg
A radiosensitizer and a prodrug form of idoxuridine; inhibits viral plaque formation in HSV-1- or HSV-2-HeLa infected cells at 100 µM; enhances radiation-induced decreases in tumor growth without reducing body weight in an HT-29 colon cancer mouse xenograft model at 1,000 mg/kg per day for six days; increases animal survival in a mouse model of lethal HSV-2 infection at 100 mg/kg every five days