Custom Peptides
Cayman Chemical ML-241hydrochlorIde 10mg
A selective inhibitor of p97 (IC50 = 0.11 µM); selective for the p97 D2 domain; disrupts the ERAD pathway, preventing the degradation of p97-dependent proteasome substrates in a reporter assay using HeLa cells (IC50 = 3.5 µM) and inducing the accumulation of ubiquitin conjugates in the nuclear plus membrane and cytosolic compartments of SW403 cells at 5 and 10 µM
Cayman Chemical 15keto FlupROSnl Isopropy 10mg
An ester derivative of fluprostenol; a potential inactive metabolite of fluprostenol isopropyl ester (travoprost); a potential impurity found in commercial preparations of fluprostenol isopropyl ester
Cayman Chemical NtrIdecnoylLHomoserIn la 10mg
An N-acyl homoserine lactone; has been found in Y. pseudotuberculosis
Cayman Chemical Valna ofcnals L Valtat 10mg
A valepotriate with diverse biological activities; inhibits nuclear export of influenza vRNP in HeLa cells at 3.6 µM; inhibits influenza virus infection in MDCK cells (IC50 = 0.19 µM); cytotoxic to GLC-4 and COLO 320 cells (IC50s = 1.4 and 3 µM, respectively); increases the number of entries into, and percentage of time spent in, the open arms of the elevated plus maze, indicating anxiolytic-like activity, and decreases serum corticosterone levels in rats at 10 mg/kg
Cayman Chemical 2CLOroN6Cyclopentyladenos 10mg
An adenosine A1 receptor antagonist; selectively binds to adenosine A1 over adenosine A2 receptors (Kis = 0.4 and 3,900 nM, respectively); inhibits forskolin-induced adenylate cyclase activity in rat fat cell membranes (IC50 = 33 nM); increases the electroconvulsive threshold in a mouse model of MES-induced seizures at 0.25 and 0.5 mg/kg; reduces infarct size in a rabbit model of coronary artery occlusion-induced myocardial infarction at 0.125 mg/kg
Cayman Chemical ThIoargInInhydrobromIde 10mg
A colorimetric arginase substrate; hydrolyzed to 2-amino-5-mercaptovaleric acid, which reacts with DTNB to form 2-nitro-5-thiobenzoate and can be quantified by colorimetric detection at 412 nm as a measure of arginase activity
Cayman Chemical aPropylamInopentIophenonh 10mg
A substituted cathinone that has propyl groups both at the α position of the cathinone structure and at the amine
Cayman Chemical GlobotrIaosylcRamIDporcIn 10mg
A sphingolipid; found in mammalian cell membranes; act as receptors for Shiga and Shiga-like toxins in vitro and in vivo; accumulate in various cells in patients with Fabry disease; interacts with HIV gp120 to prevent its interaction with chemokine co-receptors and subsequent fusion of HIV to host cell membranes
Cayman Chemical NicotinamID MononucleotID 10mg
An intermediate in the biosynthesis of NAD+ that has been used to enhance NAD biosynthesis and glucose-stimulated insulin secretion in Nampt+/- mice and high-fat diet-induced type 2 diabetes mice
Cayman Chemical Cholesterol-d6 10mg
An internal standard for the quantification of cholesterol by GC- or LC-MS
Cayman Chemical 5fluoro PB22 6hdroxquIno 10mg
Differs from 5-fluoro PB-22 by having the ester linkage inserted at the six, rather than eight, position of the quinoline moiety; intended for forensic and research purposes
Cayman Chemical LItrIntrIfluoroacetAT sal 10mg
A peptide with diverse biological activities; an agonist of the GRPR and the NMB receptor in BALB/c 3T3 fibroblasts expressing the human receptors (EC50s = 0.44 and 0.03 nM, respectively); binds to frog BB4 in CHO-K1 cells (Ki = 1.2 nM); induces contractions of isolated guinea pig gallbladder at 10-100 ng/kg; decreases food intake in rats at 4-128 UG/kg
Cayman Chemical 13 14dIhdro15keto Prostag 10mg
13,14-dihydro-15-keto PGF1α is a metabolite of PGF1α that has been reported in the rat stomach.{1164} The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in vivo production of PGF1α.{2106}
Cayman Chemical RW3trIfluoroacetate salt 10mg
An antimicrobial peptide; active against E. coli and S. aureus (IC50s = 16 and 8 µM, respectively); induces hemolysis of isolated ovine erythrocytes
