Custom Peptides
Cayman Chemical CTOPtrIfluoroacetate salt 10mg
An antagonist of the μ-opioid receptor (IC50 = 2.8 nM); selective for μ-opioid receptors over δ-opioid receptors (IC50 = 13,500 nM) and somatostatin receptors (IC50 = 24,000 nM); inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED50 = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED50 = 0.02 nmol); induces withdrawal symptoms in a mouse model of chronic morphine dependence
Cayman Chemical Progesteron 3PEG11bIotIn 10mg
An affinity probe with a hydrophilic spacer that allows progesterone to be detected or immobilized using the biotin ligand
Cayman Chemical PItofenonhydrochlorIde 10mg
An antispasmodic agent; an inhibitor of AChE (Kis = 36 and 45 μM for bovine erythrocyte and electric eel enzyme, respectively); inhibits acetylcholine-induced contractions of isolated guinea pig ileum at 2.5 μM
Cayman Chemical 1 2 3TrIundecnoyl GlycRol 10mg
A triacylglycerol; dietary administration prevents fasting-induced decreases in plasma glucose, alanine, and insulin levels, as well as the ratio of insulin to glucagon, in rats
Cayman Chemical N 2Fluorophenthyl5 2me 10mg
An inhibitor of HIF-1 signaling (IC50 = 0.32 μM in a cell-based HRE reporter assay under hypoxic conditions); inhibits hypoxia-induced increases in HIF-1α levels in MDA-MB-231, SKOV3, and HeLa cells in a concentration-dependent manner; inhibits hypoxia-induced VEGF expression and capillary-like tube formation in HUVECs; inhibits migration and invasion of MDA-MB-231 cells in wound healing and transwell assays under hypoxic conditions; reduces lung metastasis in an MDA-MB-231 mouse xenograft model at 15 and 30 mg/kg every other day
Cayman Chemical BeprIdIlhydrochlorIde 10mg
A dihydropyridine that has anti-anginal and anti-arrhythmic actions by blocking calcium channels in heart and smooth muscle; recognized as a non-selective channel blocker
Cayman Chemical DalcetrapIb 10mg
An inhibitor of CETP; inhibits plasma CETP with an IC50 value of 9 µM; in rabbits given an atherogenic diet, increases HDL, decreases VLDL, and attenuates induced atherosclerosis; in humans, inhibits CETP activity and increases HDL levels but does not reduce the risk of recurrent cardiovascular events
Cayman Chemical 4EthylethcathInonhydrochl 10mg
A substituted cathinone with potential for abuse; intended for forensic applications
Cayman Chemical Curcuma zdoara Grmacron 10mg
A sesquiterpene with diverse biological activities; inhibits PRV replication in Vero cells from 10-150 µM; enhances doxorubicin-induced cytotoxicity and apoptosis in doxorubicin-resistant MCF-7/adr cells from 50-250 µM; reduces body weight gain, visceral fat pad weight, serum insulin and plasma glucose levels, and hepatic lipid levels in a mouse model of high-fat diet-induced obesity at 5, 10, and 20 mg/kg; decreases brain MDA levels and activity of SOD and GPX, as well as reduces infarct volume in a rat model of MCAO-induced ischemia-reperfusion injury
Cayman Chemical Lentztrehalose B 10mg
A disaccharide microbial metabolite with diverse biological activities; has antioxidant activity in an ORAC assay at 100 µM; inhibits the activity of porcine kidney trehalase at 10 mM; induces autophagy in MeWo and OVK18 cells at 100 mM
Cayman Chemical PalmItoylLcarnItInchLRI 10mg
A long-chain acylcarnitine; delivers palmitate into the mitochondria for fatty acid oxidation and energy production; inhibits lecithin:cholesterol acyltransferase activity in isolated rat plasma at 500 µM; serum and hepatic levels are increased in mice during cold exposure; protects against age-induced cold sensitivity in mice
Cayman Chemical D-GlucosamIn-6-sulfate 10mg
A glycosaminoglycan; activates the glmS ribozyme from B. subtilis (200 µM); has been used to form polyvalent dendrimer conjugates that inhibit angiogenesis, cell proliferation, and scar tissue formation
Cayman Chemical PunIca grnatum PunIcaln 10mg
An ellagitannin with diverse biological activities; inhibits the SARS-CoV-2 spike RBD and ACE2 interaction (IC50 = 0.14 mg/ml); an inhibitor of carbonic anhydrase (IC50 = 1 µM); scavenges DPPH radicals and superoxide anions, as well as inhibits lipid peroxidation, in cell-free assays in a concentration-dependent manner; increases SOD and GPX activities, and decreases MDA levels, in the intestine in a mouse model of oxidative stress at 10 mg/kg per day