Custom Peptides
Cayman Chemical Uncaa yncopyla sutn 10mg
An indole alkaloid; reduces glutamate-induced cytotoxicity in primary rat cerebellar granule neurons from 100-300 µM; inhibits nicotine-induced dopamine release in PC12 cells from 1-100 µM
Cayman Chemical SalvIa ofIcnals Rosmnl 10mg
A polyphenol with diverse biological activities; an inhibitor of α-glucosidase and α amylase (IC50s = 16.4 and 40.9 UG/ml, respectively); induces apoptosis in COLO 205 cells (IC50 = ~42 µM); inhibits LPS-induced PGE2 production, as well as reduces LPS-induced NF-κB, iNOS, and COX-2 activity, in RAW 264.7 macrophages at 2.5 and 5 µM; has antinociceptive, antidepressant-like, and anxiolytic-like activity in mice at 30-100 mg/kg, respectively
Cayman Chemical 4F 4PPoxalate 10mg
A 5-HT2A receptor antagonist (Ki = 5.3 nM); selective for 5-HT2A receptors over 5-HT1C receptors (Ki = 620 nM); inhibits 5-HT-induced current in Xenopus oocytes expressing human 5-HT2A receptors (IC50 = 5.15 µM); spinal superfusion reduces the area of electrically stimulated spinal field potentials in a rat model of SNL-induced neuropathic pain at 100 µM
Cayman Chemical ACtl DIpeptID 1 cetl St 10mg
A cosmeceutical peptide; increases expression of the genes encoding the skin barrier function proteins AQP3, FLG, caspase-14, and cytokeratin 10 in primary human keratinocytes; reduces glyoxal-induced AGE formation in primary human fibroblasts
Cayman Chemical Coydals duls max. Coydn 10mg
An aporphine alkaloid with diverse biological activities; inhibits the proliferation murine L1210 lymphocytic leukemia, B16/F10 melanoma, and P388 leukemia cells from 10-100 UG/ml; binds to μ-opioid receptors (Ki = 2.82 µM) and induces [35S]GTPγS binding in CHO cells expressing human μ-opioid receptors (EC50 = 0.51 µM); active against L. donovani promastigotes (IC50 = 26.7 µM)
Cayman Chemical KIspeptIn-10zebrafIshtr 10mg
A neuropeptide; increases levels of the mRNA encoding Lh receptor, as well as Pra and Prb, in isolated zebrafish ovarian follicles at 10 ng/ml; increases luteinizing hormone serum levels in female, but not male, goldfish at 0.1 and 1 UG/g
Cayman Chemical UsmaraprIdeoxalate 10mg
A 5-HT4 partial agonist; induces reporter gene expression in CHO cells expressing recombinant human 5-HT4E receptors (EC50 = 44 nM); increases novel object exploration time in rats at 1 and 3 mg/kg; reverses scopolamine-induced memory deficits in rats when administered at doses of 1, 3, and 10 mg/kg
Cayman Chemical 4-APBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; a potential metabolite of 4-MAPB and 4-EAPB based on the published metabolism of 5-MAPB; intended for research and forensic applications
Cayman Chemical 6-MAPBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; intended for research and forensic applications
Cayman Chemical PropylhexedrInhydrochLRId 10mg
An α-adrenergic sympathomimetic amine that acts as a local vasoconstrictor; intended for research and forensic applications
Cayman Chemical Cudetaxestat 10mg
An autotaxin inhibitor (IC50 = ≤0.5 µM); reduces MDA-MB-435 cell migration (IC50 = 15 nM); reduces blood glucose levels in a glucose tolerance test, as well as baseline blood glucose levels, in mice fed a high-fat diet at 15 mg/kg twice per day for two days; reduces liver fibrosis in a CDAA/HFD mouse model of liver fibrosis at 10 mg/kg; reduces colon ulcer area and increases colon length in mouse models of acute and chronic ulcerative colitis, respectively
Cayman Chemical N8AcetylspermIdInhydrochl 10mg
An endogenous polyamine; urinary levels are increased in patients with chronic pancreatitis; blood levels are increased in patients with ischemic cardiomyopathy, as well as in patients with Parkinson’s disease
Cayman Chemical GnodermnondIol 10mg
A triterpenoid with diverse biological activities; inhibits the proliferation of Meth A and LLC1 cancer cells (IC50s = 3.4 and 12.5 UG/ml, respectively); reduces the viability of RAW 264.7 macrophages at 20 µM; inhibits fMLF- and cytochalasin B-induced superoxide generation in, and elastase release from, isolated human neutrophils (IC50s = 6.36 and 5.01 UG/ml); inhibits complement-dependent hemolysis of isolated sheep red blood cells (IC50 = 41.7 µM)
Cayman Chemical SPAA-52amonIum salt 10mg
An LMW-PTP inhibitor (Ki = 1.2 nM); greater than 8,000-fold selective for LMW-PTP over 24 phosphatases at 10 µM
Cayman Chemical Mastoparn XtrIfluoroACTAt 10mg
An antimicrobial peptide; active against several Gram-positive and Gram-negative bacteria (MICs = 3-64 and 4-256 UG/ml, respectively) and induces permeabilization of E. coli cytoplasmic membranes by 86% at 6.4 UG/ml; induces GDP/GTP exchange by Gi and binds to calmodulin (Kd = ~0.9 nM) in cell-free assays; induces necrosis in T98G cells at 20 µM; induces degranulation of isolated rat peritoneal mast cells at 128 UG/ml; induces hemolysis of isolated sheep, chicken, and human erythrocytes; increases survival, decreases disease severity, and prevents damage to jejunal villi and crypts in a mouse model of enterohemorrhagic E. coli infection at 20 mg/kg