Custom Peptides
Custom Peptides
Genscript Corporation OVA Peptide (257-264)
This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Cayman Chemical CobImetInIb 10mg
A membrane-permeable cationic dye that is a substrate for P-gp and is rapidly exported from cells with functional P-gp also accumulates within mitochondria and can inhibit oxidative phosphorylation ex/em 507/529 nm
Cayman Chemical ACtoACtylCoenzyme AsodIu 10mg
An HCV RdRp polymerase inhibitor (IC50s 0 0022-0 0107 UM for genotypes 1a and 1b) selective for HCV genotype 1 polymerases over genotypes 2 3 and 4 (IC50s 0 9-20 UM) as well as human polymerases (IC50s 100 UM)
Cayman Chemical R S-AMPAhydrate 10mg
An alkaloid with diverse biological activities increases levels of the brown fat marker proteins PRDM16 PGC-1a and UCP1 in 3T3-L1 adipocytes at 75 UM inhibits degranulation of and decreases the production of IL-6 and TNF-a in activated primary mouse BMMCs reduces serum IgE levels pulmonary immune cell infiltration and mucus secretion in a mouse model of ovalbumin-induced allergic asthma at 200 mg/kg reduces serum levels of IL-1B IL-6 IL-18 and MDA and renal cell apoptosis as well as increases protein levels of PPARY in a rat model of high-fat diet- and streptozotocin-induced type 2 diabetic nephropathy at 40 mg/kg reduces hepatic de novo lipogenesis induces hepatic autophagy and prevents weight gain insulin resistance and hepatic steatosis in a mouse model of high-cholesterol and high-fat diet-induced NAFLD at 50 mg/kg
Cayman Chemical ZolmItrIptn 10mg
An aminoindane that serves as the starting point for the synthesis of psychoactive compounds such as 56-methylenedioxy-2-aminoindane has modest analgesic and stimulatory properties intended for forensic applications
Cayman Chemical RoseoflavIn 10mg
A synthetic bile acid that acts as a potent and selective agonist of FXR (EC50 99 nM) alters gene expression that results in protection against cholestasis as well as liver fibrosis promotes the differentiation of adipocytes and enhances insulin signaling in mature adipocytes
Cayman Chemical Lapachone 10mg
A synthetic CB that displays high affinities for both the central CB1 receptor (Ki 41 nM) and the peripheral CB2 receptor (Ki 49 nM) intended for forensic and research applications
Cayman Chemical Tegaserodmaleate 10mg
A sterol glycoside with diverse biological activities active against E. coli and S. aureus inhibits a-amylase and a-glucosidase and scavenges DPPH radicals (IC50s 46.4 17 and 155 UM respectively) inhibits the proliferation of HepG2 and SMMC-7721 hepatocellular carcinoma cells (IC50s 143.4 and 138.73 Ug/ml respectively) and migration and invasion in the same cells at 50 or 100 Ug/ml increases survival and decreases the number of kidney CFUs in a mouse model of candidiasis induced by C. albicans
Cayman Chemical L-ErgothIonIn 10mg
A mycotoxin and SERCA inhibitor (IC50 0.6 UM) induces ptosis hypothermia tremor and cachexia as well as induces lethality (LD50 13 mg/kg) in rats from 11-14 mg/kg
Cayman Chemical 5-fluoro MN-18 10mg
A potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family inhibits Abl Src and Lck with IC50 values of 0.05 0.5 and 0.4 nM respectively has potential therapeutic value in some forms of cancer and fibrotic disease
Cayman Chemical TPT-260hydrochlorIde 10mg
A potent selective and irreversible inhibitor of FAAH (Ki 0.23 M) produces prolonged elevation of AEA in the brain and plasma in rats after treatment significantly and persistently reduces inflammatory pain in rats through a CB receptor-dependent mechanism
Cayman Chemical Metapramn 10mg
An endogenous agonist of the APJ receptor induces calcium mobilization in APJ-Gaq16 cells expressing human APJ (EC50 0.18 nM) inhibits HIV-1 and HIV-2 infection in NP-2/CD4/APJ cells (mean IC50 63 Ug/ml) inhibits or stimulates the expression of genes associated with apoptosis mitosis and DNA repair in IEC-6 and Caco-2 cells respectively at 0.01 UM induces the production of NO in HUVECs from 100-1000 nM increases gastric acid secretion as well as stomach histamine synthesis and secretion in rats from 20-100 Ug/kg reduces MAP in rats at 15 Ug/kg