Custom Peptides
BANGS LABORATORIES INC Bangs Quantum™ Alexa Fluor 647 MESF Kit, Fluorescence Standardization, 100 Tests
The Bangs Laboratories Quantum™ Alexa Fluor 647 MESF 5mL kit is essential for quantitative fluorescence cytometry. It standardizes fluorescence intensity units through a calibration curve correlating instrument values with MESF units. Its key benefits include accurate cellular expression analysis and evaluation of instrument performance, with microspheres labeled for environmental responsiveness.
Cayman Chemical 5-fluoro 203 10mg
A cytotoxic compound that at 1 µM activates aryl hydrocarbon receptor signaling, inducing transcription of cytochrome P450 1A1, which leads to the formation of DNA adducts and cell cycle arrest; can increase the levels of ROS as well as activate JNK, ERK, and p38MAPK in certain ovarian, breast, kidney, and colorectal cancer cells
Cayman Chemical TASQUINIMOD 10MG
An orally-active quinoline-3-carboxamide that inhibits tumor angiogenesis and supplements radiation or chemotherapy in animal models of prostate cancer
Cayman Chemical ProstaglndIn J2 10mg
A dehydration product of PGD2 formed by the elimination of the C-9 hydroxyl group; inhibits platelet aggregation (IC50 ~ 5-10 nM); has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines
Cayman Chemical 6mthylsulfInylheyl IsoTHO 10mg
An isothiocyanate with diverse biological activities; inhibits NO production in mouse peritoneal exudate macrophages at 5 µM; inhibits arachidonic acid-induced aggregation of isolated human platelets (IC50 = 21.9 µM); reduces cell survival in a panel of breast, brain, colon, lung, ovarian, renal, and prostate cancer cell lines (mean IC50 = 43.7 µM); reduces apoptosis of substantia nigral dopaminergic neurons and motor dysfunction in a mouse model of 6-OHDA-induced Parkinson's disease at 5 mg/kg twice weekly; reduces the number of lung metastases in a B16/F10 murine melanoma model
Cayman Chemical Dydrogesteron 10mg
A synthetic progestin; has no estrogenic, androgenic, glucocorticoid, or anabolic effects; an agonist of progesterone receptors (EC50 = 12.3 nM); an antagonist of androgen, mineralocorticoid, and glucocorticoid receptors (IC50s = 28.6, 82.7, and 363 nM, respectively); protects against sound stress-induced abortion in mice at 1.25 mg per animal on day five of pregnancy
Cayman Chemical MalabarIcon C 10mg
A diarylnonanoid with diverse biological activities; scavenges 59.9% of DPPH radicals at 7 μg/ml; active against S. aureus, B. subtilis, and C. albicans in vitro (MICs = 2-32 μg/ml); cytotoxic to A549, HL-60, and MCF-7 cells (IC50s = 12.3, 46.1, and 10.8 μM, respectively); inhibits SMS1 and SMS2 activity in cell lysates (IC50s = 3 and 1.5 μM, respectively); decreases body weight gain, hepatic steatosis, and hepatic and plasma triglyceride levels in a mouse model of high-fat diet-induced obesity at 0.1% in the diet
Cayman Chemical ClInofIbrate 10mg
A hypolipidemic agent; inhibits HMG-CoA reductase (IC50 = 0.47 mM); stimulates the S-indan-1-ol dehydrogenase activity of human liver AKR 1C4; reduces serum cholesterol and triglyceride levels in rats fed a normal chow pellet diet or a semisynthetic diet containing sucrose as the only carbohydrate source at 10 and 30 mg/kg
Cayman Chemical 2-C-MethylcytIdIn 10mg
A ribonucleoside with broad-spectrum antiviral activity; reduces the number of viral plaques in BHK-21 cells infected with dengue type 2, reovirus type 1, West Nile, and yellow fever RNA viruses (EC50s = 95, 26, 80, and 75 μM, respectively); inhibits HCV replication (EC50 = 2.2 μM in a replicon assay); protects MDBK cells from BVDV and HCoV infection (EC50s = 2.2 and 90 μM, respectively); reduces infectious virus yield in BHK-21 cells infected with FMDV and SVDV (EC50s = 6.4 and 45.2 μM, respectively); reduces viral shedding to undetectable levels in a mouse model of persistent norovirus infection
Cayman Chemical 4-Isocynato TEMPO 10mg
A spin label for RNA; used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by EPR spectroscopy
Cayman Chemical EmedastInfumarate 10mg
A histamine H1 receptor antagonist (Ki = 1.3 nM); selective for histamine H1 over H2 and H3 receptors (Kis = 49 and 12.43 µM, respectively), as well as α1-, α2-, and β1-adrenergic and dopamine D1 and D2 receptors, and the serotonin (5-HT) receptor subtypes 5-HT1 and 5-HT2 at 10 µM; inhibits histamine-induced phosphoinositide turnover and intracellular calcium mobilization in primary HCECs (IC50s = 1.6 and 2.9 nM, respectively); inhibits histamine-stimulated secretion of IL-6, IL-8, and GM-CSF by primary HCECs (IC50s = 2.23, 3.42, and 1.50 nM, respectively); ocular application of emedastine prior to histamine challenge inhibits vascular permeability in guinea pigs
Cayman Chemical GlycohyodeoxycholIc AcId 10mg
A major metabolite of hyodeoxycholic acid in humans; supplementation in prairie dogs fed a lithogenic diet decreases the frequency of cholesterol crystals in the gallbladder; inhibits the activity of cholesterol 7α-hydroxylase
Cayman Chemical nacardIc AcId dIen 10mg
A polyunsaturated form of anacardic acid; has antibacterial activity against MRSA and S. mutans (MICs = 12.5 and 6.25 μg/ml, respectively); has schistosomicidal activity against adult S. mansoni worms at 100 μM; inhibits soybean lipoxygenase-1 in a time-dependent manner
Cayman Chemical 19-Norndrosteron 10mg
An analytical reference standard categorized as an anabolic androgenic steroid; a major metabolite of nandrolone; intended for research and forensic applications