Custom Peptides
Cayman Chemical 5-fluoro THJ 10mg
An MDMA analog that appears to act as a serotonin-norepinephrine-dopamine releasing agent binding to and inhibiting uptake at noradrenalin and serotonin transporters (Kis 22.8 and 7.7 M and IC50s 253.4 and 108 M respectively) significantly less potent than MDMA intended for forensic and research applications
Cayman Chemical nlumbo nucIfera Lotusn 10mg
A CK2a inhibitor (IC50s 4 2 and 2 3 for the catalytic subunits CK2a and CK2a respectively) selective for CK2a over DYRK2 Plk4 MEK5 and HIPK1 -2 and -3 (IC50s 440 10000 1000 3700 3400 and 8100 nM respectively) decreases phosphorylation of Akt in HCT116 cells from 0 1-10 UM
Cayman Chemical O-desethyl DapaglIflozIn 10mg
An inhibitor of protein aggregation inhibits a-synuclein oligomer formation and PrPSc prion propagation at 10 UM inhibits brain accumulation of PrPSc in and increases survival of prion-infected mice at 1 mg/animal reduces brain tau deposition and rescues glucose metabolic decline in a human tau transgenic mouse model of Alzheimers disease dietary administration reduces the formation of a-synuclein oligomers and glial cytoplasmic inclusions microglial activation and dopaminergic neuron degradation as well as preserves motor function in a mouse model of MSA at 0 6 and 2 g/kg chow
Cayman Chemical ProstaglndIn E1 10mg
Structurally dentcal to C6 NBD ceramde but contans a saturated bond n the C-4/C-5 poston of the sphngosne backbone
Cayman Chemical OxytocInacetate 10mg
An nternal standard for the quantfcaton of 11(12)-DHET by GC- or LC-MS
Cayman Chemical 13 14dIhydro15 RProstagla 10mg
A cell-permeable reversible inhibitor of HDACs (IC50 30 nM)
Cayman Chemical A779trIfluoroacetAT salt 10mg
A natural heteroglucoside that blocks mitochondrial ADP/ATP translocases inhibiting oxidative phosphorylation
Cayman Chemical CardIolIpIn18 018 018 01 10mg
A degradation product of cefaclor formed under aqueous acidic conditions
Cayman Chemical 3-IsomngostIn 10mg
An ACSL4 inhibitor selective for ACSL4 over ACSL1 and ACSL3 inhibits formation of AA-CoA from arachidonic acid in as well as the proliferation and migration of PC3 and MDA-MB-231 cancer cells inhibits tumor growth in a PC3 mouse xenograft model at 0 25 mg/kg
Cayman Chemical 2-OL-GalactopyrnosylorI 10mg
A monosaccharide a major component of pectin increases body weight and reduces intestinal mucosal permeability in a rat model of iodoacetamide-induced functional dyspepsia at 200 400 and 800 mg/kg
Cayman Chemical DobutamInhydrochlorIde 10mg
An OEA analog that stimulates PPARa transcriptional activity (EC50 100 nM) and prolongs feeding latency in rodents (ED50 2.4 mg/kg) as potent as OEA yet resistant to enzymatic hydrolysis demonstrates weak affinity for the CB1 and CB2 receptors (Ki 33 and 26 UM respectively
Cayman Chemical GlycohyocholIc AcId 10mg
A derivative of DPA often used in formulations designed as dietary supplements
Cayman Chemical nacardIc AcId dIen 10mg
A microtubule depolymerizing agent that binds tubulin (Kd 1 3 UM) depolymerizes microtubules in both interphase and mitosis and perturbs chromosome segregation
Cayman Chemical UmbelIprenIn 10mg
An organochlorine insecticide active against bollworms (LD50 0 63 mg/g) binds to GABA receptors in rat brain membranes (IC50 30 nM) toxic to rats (LD50 18 mg/kg)