Drug Discovery Research Screening Libraries
Apexbio Technology LLC DiscoveryProbe™ Ubiquitination Compound Library, 250uL/well(10 mM solution),96 Well Racks With Screw Cap
DiscoveryProbe™ Ubiquitination Compound Library is a collection of 144 ubiquitination compounds supplied as lyophilized powder or pre-dissolved DMSO solutions. Available in stock with overnight delivery and free shipping over $500 Cost-effective and competitive price to save your findings Potent, selective and cell-permeable in inhibiting or activating target molecules Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.) Detailed files describing potency, selectivity and applications etc. Supported by published data from top peer-reviewed journals Guaranteed high quality with NMR and HPLC validation. Other sizes are also available. Please inqury us for quote.
Abcam PNU 74654, Wnt signaling pathway blocker, 25MG
MW 320.3 Da, Purity >98%. Wnt signaling pathway blocker. Inhibits Wnt/β-catenin pathway. Blocks the protein-protein interaction between β-catenin and TCF. Antitumor effects.
The product is subject to the following: Abcam Restricted Use Statement
BIOSEARCH TECHNOLOGIES INC NxSeq AmpFREE Low DNA Library Kit 48 reactions
The NxSeq AmpFREE Low DNA Library Kit is compatible with our NxSeq Adaptors or other dT-tailed, Illumina-compatible adaptors.Each NxSeq AmpFREE Low DNA Library Kit contains Enzyme Mix (EM), 2X Buffer (2XB), Ligase (LIG) and Elution Buffer (EB). Adaptors must be purchased separately.
AdipoGen Isthmin-1 mouse rec
Recombinant Protein. Mouse isthmin-1 aa 30-461 is fused at the C-terminus to a His-tag. .Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test.. Lyophilized. Contains PBS. Purity >95% SDS-PAGE. Isthmin-1 ISM1 was first identified as a gene expressed in the Xenopus midbrain hind brain organizer called isthmus, with a proposed role during early brain development. Isthmin-1 encodes a predicted ~50-kDa protein containing a signal peptide, a thrombospondin domain and an adhesion-associated domain. Isthmin-1 is important for embryonic and postnatal development. Growing evidence has shown that aberrant expression of Isthmin-1 can also affect the biological behavior of cancer. The Ism1 gene is conserved in mice and humans. A recent study showed that Ism1 is an adipokine that induces glucose uptake in human and mouse adipocytes.
AdipoGen NMNAT2 hrecHis MultiPack
Protein. Human NMNA2 aa 2-307 is fused at the N-terminus to a His-tag. Source E. coli. Lyophilized in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl plus 0.025% CHAPS. Purity >90% SDS-PAGE. Nicotinamide mononucleotide adenylyltransferase 2 NMNAT2 catalyzes the formation of NAD from nicotinamide mononucleotide NMN and ATP. Can also use the deamidated form nicotinic acid mononucleotide NaMN as a substrate but with lower efficiency. NMNAT2 also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD. It is highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. NMNAT2 is also found in the heart, skeletal muscle, pancreas and islets of Langerhans. NMNAT2 is essential for axon growth and survival. Its loss from injured axons may activate Wallerian degeneration axon degeneration induced by nerve injury, whereas NMNAT overexpression rescues axons from degeneration.
Apexbio Technology LLC DiscoveryProbe™ Ion Channel Compound Library Plus, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap
DiscoveryProbe™ Ion Channel Compound Library Plus is a unique collection of 350 ion channel-related compounds for high throughput screening (HTS) and high content screening (HCS). Available in stock with overnight delivery and free shipping over $500 Cost-effective and competitive price to save your findings Potent, selective and cell-permeable in inhibiting or activating target molecules Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.) Detailed files describing potency, selectivity and applications etc. Supported by published data from top peer-reviewed journals Guaranteed high quality with NMR and HPLC validation. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ Natural Product Library Plus, 100uL/well(10 mM solution), 96 Well Racks With Screw Cap
DiscoveryProbe™ Natural Product Library Plus is a unique collection of 1170 natural products for high throughput screening (HTS) and high content screening (HCS). Available in stock with overnight delivery and free shipping over $500 Cost-effective and competitive price to save your findings Potent, selective and cell-permeable in inhibiting or activating target molecules Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.) Detailed files describing potency, selectivity and applications etc. Supported by published data from top peer-reviewed journals Guaranteed high quality with NMR and HPLC validation. Other sizes are also available. Please inqury us for quote.
Cayman Chemical 15PGDH PosItIve CNTRLPGE 250uL
A styryl dye and an inhibitor of mechanosensitive ion channels reversibly binds to cell membranes and has been used to monitor synaptogenesis and reinnervation endocytosis and vacuole formation in vitro inhibits rapidly and slowly adapting mechanically activated currents in both capsaicin-insensitive and capsaicin-sensitive isolated rat dorsal root ganglion neurons from 0.6-15 UM ex/em 485/535 nm respectively
Abcam Tryptanthrin, immunomodulator, 25MG
MW 248.24 Da. Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC₅₀ = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tryptanthrin, immunomodulator, 5MG
MW 248.24 Da. Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC₅₀ = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
The product is subject to the following: Abcam Restricted Use Statement