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Trifluridine (NSC 529182 NSC 75520 Viroptic Trifluorothymidine TFT) is an anti-herpesvirus antiviral agent by interacting viral DNA replication used primarily on the eye
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Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM inhibits a broad panel of HIV-1 isolates from different classes inclucing a wide range of NNRTI-resistant isolates Phase 3
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Fialuridine(FIAU DRG-0098 NSC 678514) is a nucleoside analog with antiviral activity It blocks DNAsynthesis in human cytomegalovirus and hepatitis B as well as herpes simplex
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5-Fluorocytidine is a fluorinated cytidine nucleoside analog that inhibits maturation of the 45S ribosomal RNA precursor. It is used in biochemical and cellular research to probe RNA processing and nucleoside metabolism; analytical data and certificates of analysis are available for batch validation.
Inhibits maturation of the 45S ribosomal RNA precursor.
Molecular formula C9H12FN3O5 and molecular weight 261.21 g/mol.
High purity (>99.9%) as supplied; certificate of analysis available.
Analytical data available: COA, HNMR, RP-HPLC.
Storage: 4°C under nitrogen; in solution, -80°C (6 months) or -20°C (1 month).
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MW 323.2 g/mol, Purity >95%. Nucleoside monophosphate used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
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3'-O-Methylcytidine is a cytidine nucleoside analog supplied for research use. It is offered both as a solid and as pre-made stock solutions for biochemical and nucleic acid studies, and is characterized by defined molecular properties and recommended storage conditions.
Molecular formula C10H15N3O5 and molecular weight 257.24 g/mol.
Purity: 98.0% as reported by the manufacturer.
Soluble in DMSO at ≥100 mg/mL (≈388.7 mM), suitable for stock solution preparation.
Available in small solid quantities and common stock concentrations for immediate use.
Store solid protected from light at 4°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
Intended for research use only; follow appropriate safety and handling procedures.
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The EZLink NHS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
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The EZLink NHS-SS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
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Nucleoside-Analog-1 is a click chemistry reagent. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Contains an azide group
Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Compatible with molecules containing alkyne groups
Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC)
Compatible with molecules containing DBCO or BCN groups
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5-Methyluridine (m5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA). It primarily targets specific uracil sites in RNA molecules like the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing.
Generated by RNA methyltransferases (such as TrmA and RumA).
Primarily targets specific uracil sites in RNA molecules like the T arm of tRNA and rRNA.
Participates in physiological processes such as translation accuracy and ribosome function.
Stabilizes RNA folding or regulates base pairing.
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2′-O-Methyluridine-d3 is a deuterium-labeled version of 2′-O-Methyluridine. The unlabeled compound is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA to target the gene encoding apolipoprotein B, which leads to a decrease in ApoB protein levels in HepG2 cells and prevents IFN-α production in isolated human PBMCs. Decreased levels of 2'-O-Methyluridine in serum have been observed in patients with breast cancer.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
Stable heavy isotope of hydrogen.
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