Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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2,896
Tocris Bioscience™ 2-Phenylmelatonin
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 151889-03-1 Molecular Formula: C19H20N2O2
| CAS | 151889-03-1 |
|---|---|
| Molecular Formula | C19H20N2O2 |
2,897
Tocris Bioscience™ AZD 5582 dihydrochloride
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Dimeric Smac mimetic; potent IAP inhibitor
| Inhibitors | AZD 5582 dihydrochloride |
|---|---|
| Product Type | AZD 5582 dihydrochloride |
| Molecular Weight (g/mol) | 1088.21 |
| Purity | >97% |
2,898
Tocris Bioscience™ Selpercatinib
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Potent and selective RET inhibitor
| Target | Ret |
|---|---|
| CAS | 2152628-33-4 |
| Purity | 0.98 |
| Chemical Name or Material | 6-(2-Hydroxy-2-methylpropoxy)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1 ]hept-3-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H31N7O3 |
2,899
Tocris Bioscience™ BETP
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CAS: 1371569-69-5 Molecular Formula: C20H17F3N2O2S
| CAS | 1371569-69-5 |
|---|---|
| Molecular Formula | C20H17F3N2O2S |
2,900
Tocris Bioscience™ ICA 069673
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KV7.2/KV7.3 channel opener
| CAS | 582323-16-8 |
|---|---|
| Chemical Name or Material | N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C11H6ClF2N3O |
| Formula Weight | Observed MW: 269.63 |
| Assay Percent Range | >99% |
2,901
Tocris Bioscience™ iCRT 14
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CAS: 677331-12-3 Molecular Formula: C21H17N3O2S
| CAS | 677331-12-3 |
|---|---|
| Molecular Formula | C21H17N3O2S |
2,902
Tocris Bioscience™ JIB 04
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Pan Jumonji inhibitor; active in vivo
| Inhibitors | JIB 04 |
|---|---|
| Product Type | JIB 04 |
| Molecular Weight (g/mol) | 308.76 |
| Purity | >99% |
2,903
Tocris Bioscience™ Pomalidomide 4'-alkylC3-amine
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry
2,904
Tocris Bioscience™ Rimcazole dihydrochloride
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CAS: 75859-03-9 Molecular Formula: C21H29Cl2N3
| CAS | 75859-03-9 |
|---|---|
| Molecular Formula | C21H29Cl2N3 |
2,905
Tocris Bioscience™ tri-GalNAc-C5-amine
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Asialoglycoprotein receptor ligand with alkylC5 linker and amine group for onward chemistry
2,906
Tocris Bioscience™ SKF 96365 hydrochloride
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CAS: 130495-35-1 Molecular Formula: C22H27ClN2O3
| CAS | 130495-35-1 |
|---|---|
| Molecular Formula | C22H27ClN2O3 |
2,907
Tocris Bioscience™ LCL 161, phenol
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Functionalized IAP ligand for PROTACs
2,908
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Tocris Bioscience™ (R)-(+)-Bay K 8644
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Tocris Bioscience™ (R)-(+)-Bay K 8644
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CAS: 98791-67-4 Molecular Formula: C16H15F3N2O4
| CAS | 98791-67-4 |
|---|---|
| Molecular Formula | C16H15F3N2O4 |
2,909
Tocris Bioscience™ Pomalidomide
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Cereblon binder; also TNF-α inhibitor and antiangiogenic
| Target | Ubiquitin Ligase (E3) Inhibitors |
|---|---|
| CAS | 19171-19-8 |
| Purity | 98% |
| Chemical Name or Material | 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C13H11N3O4 |
| Formula Weight | Observed MW: 273.24 |
| Assay Percent Range | >98% |
2,910
Tocris Bioscience™ BX 471
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CAS: 217645-70-0 Molecular Formula: C21H24ClFN4O3
| CAS | 217645-70-0 |
|---|---|
| Molecular Formula | C21H24ClFN4O3 |