Bioactive Small Molecules
Medchemexpress LLC Amg319 | 1608125-21-8 | 99.1% | 385.40 | 5 MG
Amg319 | 1608125-21-8 | 99.1% | 385.40 | 5 MG
![Medchemexpress LLC Fmoc-Thr[PO(OBzl)OH]-OH | 175291-56-2 | 98.8% | 511.46 | 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000366475-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Fmoc-Thr[PO(OBzl)OH]-OH | 175291-56-2 | 98.8% | 511.46 | 10 G
Fmoc-Thr[PO(OBzl)OH]-OH is a threonine derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements, influencing the secretion of anabolic hormones, fuel supply during exercise, mental performance during stress-related tasks, and preventing exercise-induced muscle damage. They are recognized as beneficial ergogenic dietary substances.
- Threonine derivative
- Amino acid derivative
- Can be used as an ergogenic supplement
- May influence secretion of anabolic hormones
- May supply fuel during exercise
- May improve mental performance during stress-related tasks
- May prevent exercise-induced muscle damage
Selleck Chemical LLC D-(+)-Trehalose dihydrate 25mg 6138-23-4
Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical ANTIBODY SD-06 10mg
An inhibitor of p38α MAPK (IC50 = 0.016 µM); selective for p38α over p38β, p38γ, and p38δ MAPKs (IC50s = 0.677, >100, and >100 µM, respectively), as well as a panel of 54 additional kinases (IC50s = >3 µM for all); inhibits LPS-induced TNF-α, IL-6, and IL-1β release from primary human monocytes (IC50s = 79.4, 106.9, and 105.9 nM, respectively); decreases IL-1β-induced production of PGE2 in patient-derived RASFs (IC50 = 96.2 nM); reduces carrageenan-induced paw swelling and hyperalgesia in rats at 30 mg/kg; reduces the incidence of arthritis in a mouse model of collagen-induced arthritis; protects against joint and bone destruction in a rat model of streptococcal cell wall-induced arthritis
Cayman Chemical ANTIBODY MarImastat 5mg
A broad-spectrum inhibitor of MMPs (IC50s = 5, 6, 230, 16, and 3 nM for MMP-1, MMP-2, MMP-3, MMP-7, and MMP-9, respectively); inhibitor of TACE (IC50s = 3.8 nM and 7 μM for purified TACE and whole blood, respectively); inhibits peritoneal dissemination of implanted human gastric carcinoma TMK-1 cells in nude mice (18 mg/kg per day); inhibits lymph node metastasis of OSC-19 cells implanted in nude mice (30 mg/kg per day); delays tumor growth of human head and neck squamous cells SCC-1 xenografts in nude mice alone and when combined with chemoradiation when used at a dose of 8.7 mg/kg per day
Cayman Chemical ANTIBODY Famoxadon 25mg
A fungicide; inhibits mitochondrial complex III and electron transport in rat heart submitochondria (IC50s = 28 and 4.5 ng/ml, respectively); reduces oxygen consumption in, and induces disintegration of, P. infestans zoospores at 2 UG/ml; inhibits the growth of P. viticola on grape seedlings (EC50 = 3 UG/ml)
Apexbio Technology LLC WY-14643 (Pirinixic Acid), 250mg. Cas: 50892-23-4 MFCD: MFCD00191335. PPARα agonist,selective and highly potent
WY-14643, also known as Pirinixic Acid, has an agonistic action as peroxisome proliferator-activated receptor (PPAR). It is shown that aliphatic -substitution of WY-14643 enhances both PPAR and PPAR agonism. Other sizes are available. Please inqury us for quote.
Selleck Chemical LLC Gemcitabine HCl 100mg 122111-03-9 LY188011
Gemcitabine HCl (LY188011) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC NLRP3/AIM2-IN-3 E5801-1G
NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with species-specific effects on NLRP3 and AIM2 inflammasome-mediated pyroptosis It demonstrates potent inhibition of pyroptosis in THP-1 macrophages stimulated with LPS/nigericin with an IC50 of 0 077 M It also disrupts the interaction between NLRP3 or AIM2 and the adaptor protein ASC effectively preventing ASC oligomerization and blocking inflammasome assembly
eMolecules 841290-81-1 | Medchem Express | R406 | 5mg | 446260695 | HY-12067 | MFCD18385012 | 628.63 | C28H29FN6O8S
Medchem Express | R406 | 5mg | 446260695 | HY-12067 | 841290-81-1 | MFCD18385012 | 628.630 | C28H29FN6O8S
Medchemexpress LLC AUZ 454 | 853299-07-7 | 99.2% | 501.50 | 100 MG
AUZ 454 is a type II CDK2 inhibitor with a Kd of 8.2 nM. It inhibits CDK2 activity by competing with the binding of activating cyclins. It shows an inhibitory effect on Caki-1 and ACHN cells with WTAP overexpression and decreases colony formation through a CDK2-dependent mechanism. This product is intended for research use only.
- Inhibits CDK2 activity
- Competes with activating cyclins
- Inhibits cell proliferation in Caki-1 and ACHN cells
- Decreases colony formation in Caki-1 and ACHN cells
Medchemexpress LLC TLyP-1 peptide | 1354801-55-0 | 98.1% | 833.96 | 10 MG
tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM. Its amino acid sequence is CGNKRTR, and it specifically binds to NRP-1 to target tumor cells. This product is for research use only.
- NRP-1 targeting peptide
- IC50 of 4 μM
- Amino acid sequence: CGNKRTR
- Specifically binds to NRP-1
- Targets tumor cells
- For research use only
Medchemexpress LLC USP8-IN-1 | 2477650-96-5 | 99.1% | 387.46 | 25 MG
USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. It inhibits H1975 cell growth with a GI50 of 82.04 μM. This compound is intended for research use only.
- Inhibits USP8 with an IC50 of 1.9 μM
- Inhibits H1975 cell growth
- Purity of 99.07%
Selleck Chemical LLC 3-O-Methylquercetin E6044-1MG
3-O-Methylquercetin is a flavone isolated from Rhamnus nakaharai Hayata (Rhamnaceae) an inhibitor of cAMPand cGMP-phosphodiesterases(PDE) with an IC50 of 13 8 M and 14 3 M respectively It also inhibits -secretase with an IC50 of 6 5 M It exhibits antiviral activity and has been used in folk medicine for constipation inflammation tumors and asthma