Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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481
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495
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64,744
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481
Tocris Bioscience™ Lidocaine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.
482
Tocris Bioscience™ VH 032 amide-alkylC6-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VH 032-AlkylC6-Amine
483
Tocris Bioscience™ SR 1078
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1246525-60-9 Molecular Formula: C17H10F9NO2
| CAS | 1246525-60-9 |
|---|---|
| Molecular Formula | C17H10F9NO2 |
484
Tocris Bioscience™ NF 110
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 111150-22-2 Molecular Formula: C41H28N6Na4O17S4
| CAS | 111150-22-2 |
|---|---|
| Molecular Formula | C41H28N6Na4O17S4 |
485
Tocris Bioscience™ CyPPA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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KCa2.2 and KCa2.3 (SK) channel activator
| CAS | 73029-73-9 |
|---|---|
| Chemical Name or Material | N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H23N5 |
| Formula Weight | Observed MW: 285.39 |
| Assay Percent Range | >99% |
486
Tocris Bioscience™ ASP 2535
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective GlyT1 inhibitor
487
Tocris Bioscience™ Lalistat 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective lysosomal acid lipase (LAL) inhibitor
| CAS | 501104-16-1 |
|---|---|
| Chemical Name or Material | 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C12H18N4O3S |
| Formula Weight | Observed MW: 298.36 |
| Assay Percent Range | >98% |
488
Tocris Bioscience™ Minoxidil
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 38304-91-5 Molecular Formula: C9H15N5O
| CAS | 38304-91-5 |
|---|---|
| Molecular Formula | C9H15N5O |
490
Tocris Bioscience™ WM 3835
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Lysine acetyltransferase HBO1 (KAT7) inhibitor
| Target | Histone Acetyltransferase Inhibitors |
|---|---|
| CAS | 2229025-70-9 |
| Purity | 0.98 |
| Chemical Name or Material | N'-(4-Fluoro-5-methyl-[1,1 '-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H17FN2O4S |
491
Tocris Bioscience™ 1A-116
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
| CAS | 1430208-73-3 |
|---|---|
| Product Type | Inhibitor |
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H16F3N3 |
| Formula Weight | 307.31 |
492
Tocris Bioscience™ DPTIP
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective N-SMase2 inhibitor; brain penetrant
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H18N2O3S |
| Formula Weight | 378.45 |
493
Tocris Bioscience™ ADU-S100 disodium salt
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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STING agonist
494
Tocris Bioscience™ Idasanutlin
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C31H29Cl2F2N3O4 |
| Formula Weight | 616.49 |
495
Tocris Bioscience™ PIK 90
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent PI3K inhibitor, also used in hPSCs mesendoderm differentiation
| Target | PI 3-Kinase Inhibitors |
|---|---|
| CAS | 677338-12-4 |
| Purity | 0.98 |
| Chemical Name or Material | N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H17N5O3 |