Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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6,226 – 6,240 of 60,541 results

6,226

Medchemexpress LLC JNJ-37822681 dihydrochloride | 2108806-02-4 | 98.7% | 445.26 | 100 MG

JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder.

Potent and specific D2 receptor antagonist
Centrally active
Fast-dissociating
Moderate binding affinity for D2L receptor (Ki = 158 nM)
Potential for treating schizophrenia and bipolar disorder

Pricing & Availability

6,227

Medchemexpress LLC Nintedanib esylate | 656247-18-6 | 100.0% | 649.76 | 100 MG

Nintedanib esylate | 656247-18-6 | 100.0% | 649.76 | 100 MG

Pricing & Availability

6,228

Medchemexpress LLC Erastin2 | 1695533-44-8 | 98.6% | 623.14 | 1 ML

Erastin2 is an analog of Erastin and acts as a ferroptosis inducer. It is a potent, selective inhibitor of the system xc(-) cystine/glutamate transporter.

Ferroptosis inducer
Potent, selective inhibitor of system xc(-) cystine/glutamate transporter
Available as a 10 mM solution in DMSO
For research use only

Pricing & Availability

6,229

Medchemexpress LLC Pf-02413873 | 936345-35-6 | 99.9% | 359.44 | 10 MG

PF-02413873 is a potent, selective, fully competitive, and orally active nonsteroidal progesterone receptor (PR) antagonist. It blocks progesterone binding and PR nuclear translocation, and inhibits endometrial growth in vivo.

Potent, selective, fully competitive, and orally active
Nonsteroidal progesterone receptor antagonist
Blocks progesterone binding and PR nuclear translocation
Inhibits endometrial growth in vivo
Ki: 2.6 nM (progesterone receptor)

Pricing & Availability

6,230

Medchemexpress LLC Calf thymus DNA | 91080-16-9 | ≥97.0% | 50 MG

Calf thymus DNA is a high-quality double-stranded template DNA isolated from the thymus of male and female calves. It is used for research into the interaction between DNA and various agents.

High quality double-stranded template DNA
Isolated from the thymus of male and female calves
Used for research into DNA and agent interactions
Interacts with antiviral drug Lamivudine, studiable via emission, absorption, circular dichroism (CD), and viscosity techniques
Recommended to shake gently overnight at 0-4°C for complete dissolution to avoid shearing
Store at -20°C, protected from light
Soluble in H2O: ≥ 1 mg/mL

Pricing & Availability

6,231

eMolecules 5130-24-5 | Vinyl chloroformate | Oakwood Chemical | MFCD00000641 | 106.510 | C3H3ClO2 | 0.000 | ClC(=O)OC=C | 1g | 537708299

Vinyl chloroformate | Oakwood Chemical | 5130-24-5 | MFCD00000641 | 106.510 | C3H3ClO2 | 0.000 | ClC(=O)OC=C | 1g | 537708299

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6,232

Biotium SIN-1 50MG

SIN-1 50MG

Pricing & Availability

6,233

Cayman Chemical NBQX, Purity: ≥98%, CAS: 118876-58-7, 5 mg

An AMPA and kainate receptor antagonist (IC50s = 0.15 and 4.8 µM, respectively); selective for these receptors over NMDA receptors (IC50 = ≥90 µM); increases the latency to seizures, decreases the duration of seizures, and reduces seizure severity in a rat model of PTZ-induced epilepsy; suppresses relapse phase nicotine self-administration in rats

Pricing & Availability

6,234

Sigma Aldrich Fine Chemicals Biosciences Rifampicin | 13292-46-1 |

Rifampicin | | M. W.: 822.94 | 13292-46-1 |

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6,235

Cell Signaling Technology Nocodazole 10 mg

Nocodazole 10 mg

Pricing & Availability

6,236

Cell Signaling Technology Cytochalasin D, >98% Purity, 1 mg

Cytochalasin D is a fungal-derived toxin that acts as a potent, specific inhibitor of actin polymerization. It limits elongation at both the barbed and pointed ends of actin filaments, making it an effective tool for studying cytoskeleton-mediated processes including signal transduction, protein transport, and cell motility. This product is supplied as a lyophilized powder.

Purity: >98%
Molecular weight: 507.6 g/mol
Molecular formula: C₃₀H₃₇NO₆
Solubility: Soluble in DMSO (20 mg/mL) or ethanol (5 mg/mL)
Reconstitution: For a 5 mM stock, reconstitute 1 mg of powder in 0.39 mL of DMSO
Storage: Store lyophilized at -20°C, desiccated. Once in solution, store at -20°C and use within 3 months

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6,237

AdipoGen 3-O-Methylfluorescein

Chemical. CAS 70672-05-8. Formula C21H14O5. MW 346.33. Synthetic Used in fluorimetric studies. Fluorescent probe. Selective fluorometric substrate for CYP2C19 and CYP1A1. Reaction product of the substrate 3-O-methylfluorescein phosphate OMFP is hydrolyzed by phosphatases to yield O-methylfluorescein OMF that is detected at a 485nm excitation/525nm emission.

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6,238

AdipoGen NBD-methylhydrazine

Chemical. CAS 214147-22-5. Formula C7H7N5O3. MW 209.16. Synthetic. N-methyl-4-hydrazino-7-nitrobenzofurezan MNBDH is a new reagent for the determination of aldehydes and ketones. MNBDH reacts with carbonyl copmounds in acidic media to the corresponding MNBD-hydrazones. For example formaldehyde hydrazone formed is determined by high-performance liquid chromatography with UV/visible detection at 474 nm. MNBDH has been studied recently as a reagent with reduced interferences by ozone and nitrogen dioxide. It reacts with these oxidants to give only one product N-methyl-4-amino-7-nitrobenzofurezan MNBDA.

Pricing & Availability

6,239

Medchemexpress LLC Ras-In-2-10Mg | HY-148439-10MG

Ras-In-2-10Mg

Pricing & Availability

6,240

AdipoGen 2Me-amino-Me-7-propoxycoumarin

Chemical. CAS 351194-17-7. Formula C15H19NO3. MW 261.32. Synthetic. Fluorescent labelling.

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Bioactive Small Molecules

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Medchemexpress LLC JNJ-37822681 dihydrochloride | 2108806-02-4 | 98.7% | 445.26 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nintedanib esylate | 656247-18-6 | 100.0% | 649.76 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Erastin2 | 1695533-44-8 | 98.6% | 623.14 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pf-02413873 | 936345-35-6 | 99.9% | 359.44 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Calf thymus DNA | 91080-16-9 | ≥97.0% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Cell Signaling Technology Nocodazole 10 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Cell Signaling Technology Cytochalasin D, >98% Purity, 1 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ras-In-2-10Mg | HY-148439-10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More