Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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7,141 – 7,155 of 60,533 results

7,141

Cayman Chemical 3-hydroxy Desalkylgidazepam, Purity: ≥98%, CAS: 37891-18-2, 5 mg

An analytical reference standard categorized as a benzodiazepine; an active metabolite of gidazepam and desalkylgidazepam; has been used as a precursor in the synthesis of substituted benzodiazepinones; intended for research and forensic applications

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7,142

Medchemexpress LLC CDK2 degrader 5 | 2923574-11-0 | 99.2% | 497.54 | 25 MG

CDK2 degrader 5 (compound 12) is a degrader for CDK2, with a Dmax of >50% and ≤80% in HiBiT Assay. It plays an important role in cancer research.

Degrader for CDK2.
Dmax of >50% and ≤80% in HiBiT Assay.
Used for research purposes only.
Solid, white to off-white appearance.
Plays an important role in cancer research.

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7,143

Cayman Chemical Fuscin, Purity: ≥95%, CAS: 83-85-2, 5 mg

A fungal metabolite with diverse biological activities; inhibits binding of atractyloside to rat liver mitochondria in an ADP-dependent manner at 50 μM in a radioligand binding assay; reduces the glutathione content of rat liver mitochondria to 28% of controls at 20 μM; inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations; competes with MIP-1α for binding to CCR5 chemokine receptors in vitro (IC50 = 21 μM)

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7,144

eMolecules 4311-88-0 | Necrostatin-1 | MFCD00056916 | 1g

ChemScene | 2-Chloro-4-isopropylpyrimidine | 1g | 687354352 | CS-0197524 | 941294-36-6 | MFCD09475913 | 156.610 | C7H9ClN2

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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7,145

AdipoGen Ethionamide (5 g)

Chemical. CAS: 536-33-4. Formula: C8H10N2S. MW: 166.24. Ethionamide is an antimycobacterial antibiotic that is active against M. tuberculosis (MICs = 0.3-1.25 µg/ml). Ethionamide is a prodrug activated via oxidation by ethA (a flavin monooxygenase) and leading to the formation of an soxide metabolite, which inhibits the InhA enzyme involved in mycolic acid biosynthesis. Formulations containing ethionamide have been used in the second-line treatment of multi-drug resistant tuberculosis. Ethionamide inhibits both biofilm formation and viability of mature biofilms. Ethionamide is a thioamide analog of the first-line tuberculosis drug isoniazid.

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7,146

Cayman Chemical Tazarotene, Purity: ≥98%, CAS: 118292-40-3, 10 mg

A retinoid prodrug of tazarotenic acid; inhibits proliferation and collagen synthesis by human dermal fibroblasts (1 μM); downregulates markers of keratinocyte differentiation, keratinocyte proliferation, and inflammation and upregulates TIG1 and TIG2 in human-derived psoriatic lesions following topical administration; induces complete reduction of skin utricle diameter in the Rhino mouse (0.1% per day, topical); decreases basal cell carcinoma number and size in a Ptch1+/- mouse model of ultraviolet- or ionizing radiation-induced skin cancer when (0.1% per day, topical)

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7,147

Cayman Chemical ANTIBODY7 8-EDT 25ug

An oxylipin

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7,148

Medchemexpress LLC Odoroside A | 12738-19-1 | 1 MG

Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. It exhibits anti-cancer activity by inducing apoptosis and cell cycle arrest through the ROS/p53 signaling pathway, which leads to tumor cell death.

Extracted from Nerium oleander Linn
Exhibits anti-cancer activity
Induces apoptosis and cell cycle arrest
Acts through the ROS/p53 signaling pathway
Leads to tumor cell death
Purity of 99.73%

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7,149

Cayman Chemical Spinetoram, Purity: ≥95% (mixture), CAS: 935545-74-7, 1 mg

An insecticide; induces mortality in H. armigera third, fourth, and fifth instar larvae at 0.19 and 0.36 mg/kg in the diet; induces mortality of wild-type D. melanogaster but not D. melanogaster containing a genetic mutation in the Dα6 subunit of the nAChR (LC50s = 0.025 and 4.4 µg/cm2, respectively, in the diet)

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7,150

Medchemexpress LLC XL44 | 2637949-91-6 | 98.0% | 388.39 | 5 MG

XL44 is an hRpn13 binder that induces hRpn13-dependent apoptosis and restricts cell viability through a PCLAF-dependent mechanism. It induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins.

H Rpn13 binder
Induces hRpn13-dependent apoptosis
Restricts cell viability via PCLAF-dependent mechanism
Induces ubiquitin-dependent loss of hRpn13Pru
Induces ubiquitin-independent loss of select KEN box containing proteins

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7,151

Medchemexpress LLC XL44 | 2637949-91-6 | 98.0% | 388.39 | 25 MG

XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. It induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins.

Induces hRpn13-dependent apoptosis
Restricts cell viability by a PCLAF-dependent mechanism
Induces ubiquitin-dependent loss of hRpn13Pru
Induces ubiquitin-independent loss of select KEN box containing proteins

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7,152

Medchemexpress LLC HY-50856 100mg , Ruxolitinib CAS:941678-49-5 Purity:>98%

HY-50856 100mg Ruxolitinib CAS: 941678-49-5 Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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7,153

Medchemexpress LLC L-Alanine, N2-acetyl-L-arginyl-L-phenylalanyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl- (TFA) | 99.6% | 775.90 | 10 MG

Ac-RFAAKAA-COOH (TFA) is a heptapeptide identified as L-Alanine, N2-acetyl-L-arginyl-L-phenylalanyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl- (TFA). This white solid has an LCMS purity of 99.62% and a molecular weight of 775.90 (free base).

Appears as a white solid
Purity of 99.62% (LCMS)
Molecular weight of 775.90 (free base)
Nitrogen content: 16.35%
Peptide content: 82.41%
Tested and complies with given specifications
Sealed storage required, away from moisture
Powder storage: -80°C for 2 years, -20°C for 1 year
In solvent storage: -80°C for 6 months, -20°C for 1 month
For research use only, not fully validated for medical applications

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7,154

Cayman Chemical Deferitrin, Purity: ≥98%, CAS: 239101-33-8, 5 mg

An iron chelator and a derivative of desferrithiocin; binds iron in a 2:1 (ligand:iron) ratio; inhibits the proliferation of L1210 murine leukemia cells (IC50 = 17 µM); induces iron excretion in iron-overloaded C. apella monkeys and beagle dogs with an ICE of 14.5 and 9.3%, respectively at 150 µmol/kg; reduces fecal and urine iron levels by 607 and 357 µg/kg in C. apella monkeys and beagle dogs, respectively

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7,155

Medchemexpress LLC NADH (disodium salt) | 606-68-8 | 99.9% | 709.40 | 1 ML

NADH (disodium salt) | 606-68-8 | 99.9% | 709.40 | 1 ML

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Bioactive Small Molecules

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Medchemexpress LLC CDK2 degrader 5 | 2923574-11-0 | 99.2% | 497.54 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Odoroside A | 12738-19-1 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC XL44 | 2637949-91-6 | 98.0% | 388.39 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC XL44 | 2637949-91-6 | 98.0% | 388.39 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-50856 100mg , Ruxolitinib CAS:941678-49-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC L-Alanine, N2-acetyl-L-arginyl-L-phenylalanyl-L-alanyl-L-alanyl-L-lysyl-L-alanyl- (TFA) | 99.6% | 775.90 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NADH (disodium salt) | 606-68-8 | 99.9% | 709.40 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More