Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,336
Tocris Bioscience™ A 410099.1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity XIAP antagonist
| Product Type | Antagonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H40N4O3.HCl |
| Formula Weight | 505.09 |
1,337
Tocris Bioscience™ Paroxetine maleate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent and selective 5-HT uptake inhibitor
| Inhibitors | Paroxetine maleate |
|---|---|
| Product Type | Paroxetine maleate |
| Molecular Weight (g/mol) | 445.44 |
| Purity | >99% |
1,338
Tocris Bioscience™ Torin 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1222998-36-8 Molecular Formula: C35H28F3N5O2
| CAS | 1222998-36-8 |
|---|---|
| Molecular Formula | C35H28F3N5O2 |
1,339
Tocris Bioscience™ BSJ-04-132
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Selective Cdk4 degrader
1,340
Tocris Bioscience™ SCH 336
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Highly potent and selective CB2 inverse agonist
| CAS | 447459-51-0 |
|---|---|
| Chemical Name or Material | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C23H25NO8S3 |
| Formula Weight | Observed MW: 539.64 |
| Assay Percent Range | >98% |
1,341
Tocris Bioscience™ LRRK2-IN-1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1234480-84-2 Molecular Formula: C31H38N8O3
| CAS | 1234480-84-2 |
|---|---|
| Molecular Formula | C31H38N8O3 |
1,342
Tocris Bioscience™ JZP 430
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
| Target | Hydrolase Inhibitors |
|---|---|
| CAS | 1672691-74-5 |
| Purity | >98% |
| Chemical Name or Material | 4-(4-Morpholinyl)-1,2,5-thiadiazol-3-yl N-cyclooctyl-N-methylcarbamate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H26N4O3S |
| Formula Weight | 354.47 |
1,343
Tocris Bioscience™ BAY 6035
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective SMYD3 inhibitor
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H28N4O3 |
| Formula Weight | 396.48 |
1,344
Tocris Bioscience™ c-Di-AMP sodium salt
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Endogenous STING and DDX41 agonist; activates STING-dependent signaling
1,345
Tocris Bioscience™ Valsartan
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High affinity, selective AT1 antagonist
| Inhibitors | Valsartan |
|---|---|
| Product Type | Valsartan |
| Molecular Weight (g/mol) | 435.52 |
| Purity | >99% |
1,346
Tocris Bioscience™ CITFA
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Potent G protein-coupled estrogen receptor (GPER) agonist
1,347
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Tocris Bioscience™ 3',2'-cGAMP sodium salt
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Tocris Bioscience™ 3',2'-cGAMP sodium salt
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Induces expression of STING and STING-related genes; antiviral
1,348
Tocris Bioscience™ NIR Dye s775z, NHS
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Bright and photostable non-aggregating near-IR cyanine dye. Reactive group: NHS ester
1,349
Tocris Bioscience™ 3-Azido-7-hydroxycoumarin
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Click-reactive fluorescent dye
1,350
Tocris Bioscience™ EN 219
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Covalent RNF114 ligand
| Target | RNF114 |
|---|---|
| CAS | 380351-29-1 |
| Purity | 0.98 |
| Chemical Name or Material | 1-[3,5-bis(4-Bromophenyl)-4,5-dihydro-1 H-pyrazol-1-yl]-2-chloroethanone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H13Br2ClN2O |