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Reagents containing reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. Ideal for various applications including conjugation reactions, biomolecule labeling, and molecular purification.
Also available in 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Fmoc-Val-Cit-PAB-PNP is a linker used in Antibody-Drug Conjugation (ADC). Purity 98.05%
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An amine-reactive reagent; has been used as a derivatization reagent to identify PTMs in lysine-rich proteins and novel cell surface proteins of R. rickettsii
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Phytanic acid is a saturated 20-carbon branched-chain fatty acid which can only be derived from dietary sources. In cases of peroxisomal disorders, elevated levels of phytanic acid have been observed, and this is linked to diseases such as infantile phytanic acid storage disease and Refsum’s disease.{1912}
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A metabolite of norcholic acid and derivative of deoxycholic acid; hepatic levels are decreased in rats in a high-fat diet model of NAFLD; serum levels are lower in men compared with women; has commonly been used as an internal standard for the quantification of bile acids in various sample types by GC- and LC-MS
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A metabolite of lithocholic acid; water soluble and the primary form of lithocholic acid in the bile duct; forms a complex with calcium in vitro; biliary secretion increased in a rat model of streptozotocin-induced diabetes
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Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker that bears N-hydroxysuccinimide (NHS) ester and maleimide groups, which react with primary amines and sulfhydryl groups, respectively. It inhibits the end-to-end annealing of stabilized Microtubules (MTs).