Crosslinking Reagents
Indofine Chemical METHOTREXATE, Products for Life Science, 59-05-2, 100 mg
METHOTREXATE, Products for Life Science, 59-05-2, 100 mg
Advanced Biomatrix PhotoHA-Soft Methacrylated hyaluronic acid softer hydrogels 100 mg
PhotoHA is 100 mg of lyophilized methacrylated hyaluronic acid (GM-HA). PhotoHA provides 3D hyaluronic acid hydrogels with the unique attributes to be prepared at various concentrations and photocrosslinked to provide various gel stiffness. GM-HA forms softer hydrogels than HAMA.
Medchemexpress LLC Octanedioic acid, 1,8-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester | 82436-77-9 | 98.0% | 528.47 g·mol⁻¹ | C16H20N2O14S2 | 50 MG
BS3 Crosslinker is a water-soluble, non-cleavable homobifunctional crosslinker that reacts with primary amines to form stable amide bonds. It contains sulfo-NHS ester groups that enable efficient conjugation in aqueous buffers, making it suitable for protein crosslinking and antibody-drug conjugate synthesis in research applications.
- Water soluble and membrane impermeable, enabling reactions in aqueous buffers.
- Reacts with primary amines via NHS-ester chemistry for efficient conjugation.
- Forms stable, non-cleavable amide bonds for durable linkages.
- Compatible with antibody-drug conjugate (ADC) and protein crosslinking workflows.
- Supplied with defined purity and characterized molecular weight for reproducibility.
- Available in small lab-friendly pack sizes for research use.
Medchemexpress LLC PC SPDP-NHS carbonate ester | 2279944-61-3 | MFCD31811480 | 95.0% | 608.64 | C25H28N4O10S2 | 5 MG
PC SPDP-NHS carbonate ester is a photocleavable carbonate NHS ester linker used for bioconjugation and the construction of antibody-drug conjugates (ADCs). It provides an NHS carbonate reactive site for coupling to primary amines and a photolabile unit that enables controlled payload release.
- Cleavable photocleavable linker suitable for ADC synthesis
- Contains an NHS carbonate reactive group for amine conjugation
- Purity 95.0%
- Molecular weight 608.64
- Soluble in common organic solvents such as DMSO
- Supplied in small research pack sizes for laboratory use
eMolecules Ambeed DSG Crosslinker 1mg 702437996 A880434 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
Ambeed DSG Crosslinker 1mg 702437996 A880434 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
Medchemexpress LLC Sulfo-cyanine5 DBCO | 981.27 | C53H57KN4O8S2 | 10 MG
Sulfo-Cyanine5 DBCO is a water-soluble near-infrared fluorescent dye bearing a dibenzocyclooctyne (DBCO) reactive group for copper-free click chemistry. It is intended for bioorthogonal labeling of azide-containing biomolecules and fluorescence imaging in aqueous media.
- Near-infrared fluorescent dye (Ex/Em 646/670 nm).
- DBCO reactive handle enables strain-promoted alkyne-azide cycloaddition (SPAAC).
- Water-soluble sulfonated cyanine core for labeling in aqueous buffers.
- Suitable for conjugation to proteins, peptides, and nucleic acids.
- Store sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Sulfo-LC-SPDP sodium | 169751-10-4 | 527.57 | C18H22N3NaO8S3 | 10 MG
Sulfo-LC-SPDP sodium is a thiol-cleavable, heterobifunctional linker used to conjugate payloads to antibodies via a disulfide bond. It provides a water-soluble long-chain spacer and a pyridinyldithiol reactive group to enable payload release under reducing conditions. Intended for research use only.
- cleavable disulfide linker for controlled payload release
- heterobifunctional reactivity for amine and thiol conjugation
- water-soluble sodium salt for improved aqueous handling
- long-chain spacer reduces steric hindrance at the conjugation site
- suitable for antibody-drug conjugate synthesis and bioconjugation workflows
- molecular weight 527.57 and formula C18H22N3NaO8S3
Medchemexpress LLC Trans-sulfo-SMCC | 1286837-77-1 | 90.9% | 414.39 g/mol | C16H18N2O9S | 100 MG
trans-Sulfo-SMCC is a non-cleavable, membrane-permeable crosslinker used for antibody-drug conjugate (ADC) construction and general bioconjugation. It contains maleimide and N-hydroxysuccinimide (NHS) ester functionalities that enable stable conjugation between sulfhydryl and amino groups to form non-cleavable linkages.
- Non-cleavable linker suitable for ADC construction.
- Membrane permeable for potential intracellular delivery.
- Maleimide and NHS-ester reactive groups for thiol-to-amine conjugation.
- Solid, white to off-white, available in multiple quantities including 100 mg.
- Stable as a powder at -20 °C for long-term storage; in solvent stability varies.