Protein Modification Reagents
Medchemexpress LLC Mal-amido-PEG6-acid | 1334177-79-5 | 99.3% | 250 MG
Mal-amido-PEG6-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. These PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Contains two distinct ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets the protein of interest
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium histolyticum Sigma Blend Type H, ≥1.0 FALGPA units/mg solid | 9001-12-1 | MFCD00130830 | 500mg
Collagenase from Clostridium histolyticum Sigma Blend Type H, ≥1.0 FALGPA units/mg solidPurity: MW: | 9001-12-1 | MFCD00130830 | 500mg
Medchemexpress LLC Hydroxy-PEG4-CH2COOH | 70678-95-4 | ≥97.0% | C10H20O7 | 500 MG
Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Bis-aminooxy-PEG4 | 98627-72-6 | 96.0% | C10H24N2O6 | 100 MG
Bis-aminooxy-PEG4 is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras), which contain two distinct ligands connected by a linker. One ligand targets an E3 ubiquitin ligase, while the other targets a protein of interest. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker for PROTAC synthesis
- Enables selective degradation of target proteins
- Utilizes the ubiquitin-proteasome system
- Light yellow to yellow liquid appearance
eMolecules 1314378-14-7 | Fmoc-PEG4-NHS ester | Broadpharm | MFCD20227659 | 584.622 | C30H36N2O10 | 97.000 | O=C(CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12)ON1C(=O)CCC1=O | 1g | 229582925
Fmoc-PEG4-NHS ester | Broadpharm | 1314378-14-7 | MFCD20227659 | 584.622 | C30H36N2O10 | 97.000 | O=C(CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12)ON1C(=O)CCC1=O | 1g | 229582925
Medchemexpress LLC Tos-PEG4-t-butyl ester | 217817-01-1 | 50 MG
Tos-PEG4-t-butyl ester is a PROTAC linker with a PEG composition. It is utilized in the synthesis of various PROTACs.
- Molecular weight: 432.53
- Chemical formula: C20H32O8S
- Appearance: Liquid
- Color: Colorless to light yellow
Medchemexpress LLC Mal-amido-PEG1-C2-NHS ester | 1260092-50-9 | 99.7% | 381.34 g/mol | C16H19N3O8 | 25 MG
Mal-amido-PEG1-C2-NHS ester is a heterobifunctional PEG1-based linker containing a maleimide and an N-hydroxysuccinimide (NHS) ester. It is designed for bioconjugation applications, enabling selective labeling of amines and thiols and supplied as a solid with recommended solubility in DMSO.
- Heterobifunctional maleimide-NHS linker for bioconjugation.
- Enables amine labeling via NHS ester and thiol conjugation via maleimide.
- High purity suitable for research applications and ADC linker chemistry.
- Available in small pack sizes for laboratory use and soluble in DMSO.
- Molecular weight 381.34 g/mol and CAS 1260092-50-9.
Medchemexpress LLC Bromoacetamido-PEG4-C2-Boc | 1807521-00-1 | 1 G
Bromoacetamido-PEG4-C2-Boc is a laboratory chemical used for the manufacture of substances. It is stable under recommended storage conditions.
- Harmful if swallowed
- Causes skin and serious eye irritation
- May cause respiratory irritation
- Store in a cool, well-ventilated area away from direct sunlight and ignition sources
- Recommended storage for pure form: -20°C for 3 years or 4°C for 2 years
- Recommended storage for in solvent: -80°C for 6 months or -20°C for 1 month
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG8-CH2COOH | 5 g | CAS 868594-52-9 | MDL MFCD27635163
Fmoc-NH-PEG8-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 868594-52-9
- MDL: MFCD27635163
- InChIKey: JRLUSGRARXJCNA-UHFFFAOYSA-N
- Molecular Weight: 649.734
- Molecular Formula: C33H47NO12
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azatriacontan-30-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC m-PEG5-succinimidyl carbonate | 1058691-00-1 | 98.0% | 393.39 g/mol | C16H27NO10 | 25 MG
m-PEG5-succinimidyl carbonate is a monomethoxy polyethylene glycol (PEG) linker with five ethylene glycol units terminated as a succinimidyl carbonate active ester. It is supplied as a reactive linker for conjugation to primary amines in bioconjugation workflows.
- Non-cleavable 5-unit PEG spacer for conjugation.
- Activated succinimidyl carbonate for efficient amine coupling.
- Suitable for ADC and PROTAC synthesis applications.
- Appearance: colorless to light yellow liquid; supplied in small mg quantities for research use.
![Medchemexpress LLC 4,7,10,13-tetraoxa-16-azaheneicosanamide, N-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethyl] | 1070801-79-4 | 96.0% | 697.32 g/mol | C31H57ClN4O9S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000297693.png-250.jpg)
Medchemexpress LLC 4,7,10,13-tetraoxa-16-azaheneicosanamide, N-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethyl] | 1070801-79-4 | 96.0% | 697.32 g/mol | C31H57ClN4O9S | 10 MG
Biotin-PEG4-amide-PEG2-C6-Cl is a biotinylated polyethylene glycol (PEG) linker with an amide and a PEG2-C6-chloro reactive terminus. It is supplied as a white to off-white solid for use as a biotinylation reagent, linker synthesis, and probe conjugation in research applications.
- Purity 96.0%.
- Molecular weight 697.32 g/mol.
- Chemical formula C31H57ClN4O9S.
- Appearance white to off-white solid; supplied in small milligram packages.
- Storage: 4°C sealed; in solvent store at -80°C up to 6 months, -20°C up to 1 month.
- Contains a C6-chloro reactive terminus suitable for alkylation or conjugation reactions.