Protein Modification Reagents
Medchemexpress LLC PC DBCO-PEG4-NHS ester | 2055025-02-8 | 96.9% | C47H55N5O16 | 10MG
PC DBCO-PEG4-NHS ester is a photocleavable PEG-based linker containing a dibenzocyclooctyne (DBCO) moiety and an N-hydroxysuccinimide (NHS) carbonate reactive group. It is designed for bioconjugation workflows, enabling coupling to primary amines and strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners, with the option of light-triggered cleavage when required.
- Photocleavable linker enabling light-triggered cleavage.
- DBCO moiety for strain-promoted alkyne-azide cycloaddition (SPAAC).
- NHS carbonate group for efficient coupling to primary amines.
- PEG4 spacer improves solubility and reduces steric hindrance.
- Suitable for bioconjugation workflows and PROTAC synthesis.
- Supplied as a solid, white to light yellow, with high listed purity.
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | 98.5% | 406.39 | C19H22N2O8 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202474.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | 98.5% | 406.39 | C19H22N2O8 | 50 MG
Ald-Ph-amido-PEG2-C2-NHS ester is a non-cleavable 2-unit PEG linker used for antibody-drug conjugation (ADC). It features an N-hydroxysuccinimide (NHS) ester for amine-reactive coupling and a 4-formylbenzoyl aldehyde handle for further derivatization. Supplied as a colorless to light yellow liquid, the material is validated by 1H NMR and LCMS.
- Non-cleavable 2-unit polyethylene glycol (PEG) linker for ADC chemistry.
- N-hydroxysuccinimide (NHS) ester for amine-reactive conjugation.
- 4-formylbenzoyl aldehyde for further derivatization.
- Molecular formula C19H22N2O8; molecular weight 406.39.
- CAS number 1807521-07-8.
- Purity (LCMS) 98.5%.
- Appearance colorless to light yellow liquid.
- Storage: pure form -20°C up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.
- Pack size typically supplied as 50 MG.
![eMolecules 2086689-05-4 | 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane | Broadpharm | MFCD30723261 | 464.472 | C18H32N4O10 | 98.000 | OC(=O)CCOCC(COCCC(O)=O)NC(=O)CCOCCOCCOCCN=[N+]=[N-] | 50mg | 393649473](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1662113.jpg-250.jpg)
eMolecules 2086689-05-4 | 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane | Broadpharm | MFCD30723261 | 464.472 | C18H32N4O10 | 98.000 | OC(=O)CCOCC(COCCC(O)=O)NC(=O)CCOCCOCCOCCN=[N+]=[N-] | 50mg | 393649473
2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane | Broadpharm | 2086689-05-4 | MFCD30723261 | 464.472 | C18H32N4O10 | 98.000 | OC(=O)CCOCC(COCCC(O)=O)NC(=O)CCOCCOCCOCCN=[N+]=[N-] | 50mg | 393649473
TARGETMOL CHEMICALS INC DMG-PEG 2000 200MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. DMG-PEG 2000 (DMG-PEG2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG 2000 have been used in the development of lipid nanoparticles for the delivery of mRNA-based vaccines. purity: 98%
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol 98 (HPLC), 99.0 (titration), 3483-12-3, MFCD00004877
DL-Dithiothreitol 98 (HPLC), 99.0 (titration)
Soltec Ventures Inc Tris(2-carboxyethyl)phosphine hydrochloride | 51805-45-9 | MFCD00145469 | 25 g
Tris(2-carboxyethyl)phosphine hydrochloride | Mol Wt: 286.65 | 51805-45-9 | MFCD00145469 | 25 g
Abcam Kinase Assay Buffer I, 5ML
Stock solution of buffer used for assaying kinase protein.
The product is subject to the following: Abcam Restricted Use Statement
AG Scientific Inc Dithiothreitol, DTT, 10 G
Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.CAS Number: 3483-12-3Molecular Weight: 154.2Chemical Formula: C4H10O2S2Solubility: 10% solution in water. Clear and colorlessStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
AG Scientific Inc Dithiothreitol, DTT, 1 KG
Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.CAS Number: 3483-12-3Molecular Weight: 154.2Chemical Formula: C4H10O2S2Solubility: 10% solution in water. Clear and colorlessStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC PROTAC EGFR degrader 11 | 3034244-71-5 | 99.2% | 991.61 | 1 MG
PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. It binds CRBN-DDB1 with a Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.
- PROTAC degrader for epidermal growth factor receptor (EGFR).
- DC50 <100 nM.
- Binds CRBN-DDB1 with a Ki of 36 nM.
- Degrades EGFR, focal adhesion kinase (FAK), and RSK1.
- Inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.