Protein Modification Reagents
Medchemexpress LLC Biotin-PEG2-aldehyde | 00-00-0 | 95.0% | 387.5 g/mol | C17H29N3O5S | 5 MG
Biotin-PEG2-aldehyde is a biotinylated PEG linker bearing a terminal aldehyde functional group for bioconjugation and PROTAC synthesis. The short PEG2 spacer increases aqueous solubility and provides a flexible linkage between the biotin tag and attached payloads.
- Terminal aldehyde enables chemoselective conjugation (hydrazone, oxime, reductive amination)
- PEG2 spacer improves aqueous solubility and flexibility
- Biotin tag enables affinity capture with streptavidin-based reagents
- Compatible with PROTAC and probe synthesis workflows
- High purity suitable for research use (95.0%)
- Available in small research-friendly pack sizes
Medchemexpress LLC HyNic-PEG2-DBCO | 2741281-12-7 | >98.0% | 610.72 g/mol | C34H38N6O5 | 5 MG
HyNic-PEG2-DBCO is a bifunctional PEG2 linker combining a hydrazinonicotinamide (HyNic) reactive handle with a dibenzocyclooctyne (DBCO) moiety for orthogonal bioconjugation. Supplied as a solid (5 mg), it is intended for research use in PROTAC synthesis, protein/antibody conjugation, and copper-free click-chemistry workflows.
- Provides orthogonal conjugation: hydrazone formation and copper-free SPAAC.
- Contains HyNic and DBCO reactive groups for selective coupling.
- PEG2 spacer improves solubility and reduces steric hindrance.
- High purity (>98%) suitable for research applications.
- Supplied as a solid powder for straightforward storage and handling.
- Recommended storage refrigerated at 2-8 °C to preserve stability.
ABclonal Technology MAN1C1 Rabbit pAb
Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in extracellular exosome.
Cayman Chemical Boc-NH-PEG3-OH 50mg
A PEGylated building block; has been used as a spacer in biotinylated heterobifunctional cross-linker agents; has been used as a spacer in near infrared imaging probes for CYP1B1, which is expressed in a variety of tumors; has also been used in the synthesis of graftable peptidomimetics that bind to human αVβ3 integrin and inhibit adhesion of human osteoprogenitor cells to vitronectin
Medchemexpress LLC Vh285-peg4-c4-cl | 1799506-07-2 | MFCD34601688 | >98.0% | 799.42 g·mol⁻¹ | C41H55ClN4O8S | 5 MG
VH285-PEG4-C4-Cl is a VHL-ligand-HaloTag conjugate designed as a targeted protein degrader for use in cellular and biochemical assays. It connects a VH285-based VHL ligand to a HaloTag-targeting moiety via a PEG4-C4 linker to induce proteasomal degradation of HaloTag fusion proteins. Supplied for research use with high stated purity and available in small quantities or as a DMSO solution.
- Highly potent degrader with a DC50 of 19 nM.
- Can induce up to 90% degradation of GFP-HaloTag7 in cells.
- VHL ligand-HaloTag conjugate with a PEG4-C4 linker for targeted engagement.
- Supplied with reported purity ≥98% and molecular weight 799.42 g·mol⁻¹.
- Available in small mg quantities or as a 10 mM solution in DMSO for reconstitution.
- Suitable for cellular and biochemical studies of targeted protein degradation.
American Research Products Inc ADC MMAE IGG LABELLING AND INT
5000265577 ADC MMAE IGG LABELLING AND INT
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 5 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 25 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Thp-peg4-pyrrolidine(n-me)-ch2oh | 2378261-81-3 | 95.0% | 25 MG
THP-PEG4-Pyrrolidine(N-Me)-CH2OH is a PEG-based PROTAC linker. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins, typically consisting of two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTAC K-Ras degrader-1.
- Enables PROTACs to leverage the ubiquitin-proteasome system.
- PROTAC K-Ras degrader-1 shows ≥70% degradation efficacy in SW1573 cells.
Chemscene ChemScene | Mal-PEG6-NHS ester | 250MG | CS-0104984 | 0.98 | 1599472-25-9| MFCD20926374 | 530.52
ChemScene | Mal-PEG6-NHS ester | 250MG | CS-0104984 | 0.98 | 1599472-25-9| MFCD20926374 | 530.52