Protein Modification Reagents
Medchemexpress LLC 3,6,9,12-tetraoxatridecan-1-amine | 85030-56-4 | MFCD11041099 | 98.8% | 207.27 g/mol | C9H21NO4 | 500 MG
m-PEG4-Amine is a short polyethylene glycol (PEG4) amine reagent used as a linker in chemical biology applications. It is commonly used in the synthesis of proteolysis targeting chimeras (PROTACs) and can serve as a cleavable linker in antibody-drug conjugate (ADC) construction. The reagent is supplied at research-grade purity for laboratory use.
- Short PEG4 amine linker for conjugation chemistry.
- Useful for PROTAC design and linker optimization.
- Functions as a cleavable linker for ADC synthesis.
- High purity suitable for research applications.
- Molecular weight 207.27 g/mol; formula C9H21NO4.
Medchemexpress LLC Mal-PEG2-gly-gly-phe-gly-exatecan | 1599439-54-9 | 98.6% | 1149.18 | C57H65FN10O15 | 5 MG
A drug-linker conjugate used in antibody-drug conjugate (ADC) synthesis and cancer research. It consists of an exatecan payload linked via a maleimide-PEG2-gly-gly-phe-gly linker. For research use only.
- Suitable for antibody-drug conjugate synthesis
- High purity: 98.6%
- Molecular weight: 1149.18 g/mol
- Chemical formula: C57H65FN10O15
- Soluble in DMSO
- Store at -20°C and protect from light
Cayman Chemical C16 MPEG 2000 CeramIded181mg
A PEGylated form of C16 ceramide; has been used in the generation of microspheres, LNPs, and liposomes for the delivery of small molecules, mRNA, and plasmid DNA in vitro and in vivo; liposomes containing C16 ceramide-mPEG(2000) with a stearylated-INF7 and have been used to transfect plasmid DNA into MFLM-4 cells; microspheres containing C16 ceramide-mPEG(2000) and encapsulating oxaliplatin increase survival and decrease the number of small intestine, colon, and cecum polyps in an Apc+/Minz spontaneous colorectal adenoma mouse model
Medchemexpress LLC DBCO-PEG2-DBCO | 2639395-48-3 | C44H42N4O6 | 25 MG
DBCO-PEG2-DBCO is a click chemistry reagent that contains a DBCO group. It functions as a PEG linker with two terminal DBCO groups. These DBCO groups are frequently used for copper-free Click Chemistry reactions due to their strain-promoted high energy. The hydrophilic PEG chain in DBCO-PEG2-DBCO enhances its water solubility. This product is reagent grade and intended for research use only.
- Contains a DBCO group
- Functions as a PEG linker with two terminal DBCO groups
- Commonly utilized in copper-free click chemistry reactions
- Exhibits strain-promoted high energy
- Hydrophilic PEG chain enhances water solubility
- Reagent grade
- Intended for research use only
Medchemexpress LLC Mal-amido-PEG6-NHS ester | 1137109-21-7 | 98.8% | 601.60 | 500 MG
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Dspe-peg-fluor 647 | 95.4% | 5000 | 1 MG
DSPE-PEG-Fluor 647, MW 5000 is a PEGylated lipid with a DSPE group and a Fluor 647 fluorophore. DSPE is a phospholipid. Fluor 594 is a red water-soluble dye.
- Pegylated lipid
- Contains DSPE group and a Fluor 647 fluorophore
- DSPE is a phospholipid
- Fluor 594 is a red water-soluble dye
Medchemexpress LLC Tetraglyme | 143-24-8 | 99.93% | 222.28 | 500 G
Me-PEG4-Me is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Is a peg-based protac linker
- Useful in the synthesis of protacs
Medchemexpress LLC (S,R,S)-AHPC-PEG1-N3 (VH032-PEG1-N3) | 2101200-09-1 | 98.8% | 557.67 g/mol | C26H35N7O5S | 500 MG
(S,R,S)-AHPC-PEG1-N3 is an E3 ligase VHL ligand-linker conjugate containing an AHPC-based VHL ligand and a single-unit PEG linker terminated with an azide. It is supplied as a powder for research use and is used as a building block in PROTAC synthesis and click-chemistry conjugation.
- Synthesized E3 ligase ligand-linker conjugate.
- Incorporates VHL ligand based on (S,R,S)-AHPC.
- Features a 1-unit PEG linker for modular conjugation.
- Azide-terminated linker enables click chemistry reactions.
- High solubility in DMSO, insoluble in water.
- Powder stable at -20°C for extended storage.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 5 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Mal-amido-PEG2-C2-acid | 756525-98-1 | 99.8% | 328.32 | 1 G
Mal-amido-PEG2-C2-acid is a PROTAC linker that is PEG-based and can be utilized in the synthesis of PROTACs. PROTACs themselves consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only and is not sold to patients.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
