Protein Modification Reagents
Medchemexpress LLC N3-PEG3-VC-PAB-MMAF | 2757277-32-8 | 100.0% | 1352.62 | C66H105N13O17 | 25 MG
N3-PEG3-VC-PAB-MMAF is a drug-linker conjugate for antibody-drug conjugate (ADC) research that combines an azide-functionalized PEG3 spacer, a valine-citrulline (VC) cleavable linker with a para-aminobenzyl (PAB) self-immolative spacer, and the tubulin inhibitor MMAF to enable click chemistry conjugation and controlled payload release.
- Azide-functionalized PEG3 spacer for click chemistry conjugation.
- VC-PAB cleavable linker enabling enzymatic release of payload.
- Includes MMAF payload for tubulin inhibition in ADC constructs.
- White to off-white solid with high purity suitable for research use.
- Available in small milligram pack sizes for synthesis workflows.
eMolecules 14-(Amine-PEG5-ethylcarbamoyl)tridecanoic-t-butyl ester | Broadpharm |576.816 | C30H60N2O8 | 95.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCN | 100mg | 784455389
14-(Amine-PEG5-ethylcarbamoyl)tridecanoic-t-butyl ester | Broadpharm |576.816 | C30H60N2O8 | 95.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCN | 100mg | 784455389
![eMolecules 2107273-36-7 | Bis-(N,N'-amine-PEG3)-Cy5, TFA salt | Broadpharm855.430 | C43H62ClF3N4O8 | 95.000 | [Cl-].OC(=O)C(F)(F)F.CC1(C)\C(=C/C=C/C=C/C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)N(CCOCCOCCOCCN)c2ccccc12 | 5mg | 306709104](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203309.JPG-250.jpg)
eMolecules 2107273-36-7 | Bis-(N,N'-amine-PEG3)-Cy5, TFA salt | Broadpharm855.430 | C43H62ClF3N4O8 | 95.000 | [Cl-].OC(=O)C(F)(F)F.CC1(C)\C(=C/C=C/C=C/C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)N(CCOCCOCCOCCN)c2ccccc12 | 5mg | 306709104
Bis-(N,N'-amine-PEG3)-Cy5, TFA salt | Broadpharm | 2107273-36-7855.430 | C43H62ClF3N4O8 | 95.000 | [Cl-].OC(=O)C(F)(F)F.CC1(C)\C(=C/C=C/C=C/C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)N(CCOCCOCCOCCN)c2ccccc12 | 5mg | 306709104
Medchemexpress LLC Alkyne-SNAP | 1104822-07-2 | C18H18N6O2 | 1 MG
Alkyne-SNAP is an alkyne-conjugated benzylguanine. Its benzylguanine moiety reacts with the SNAP-tag, enabling irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for subsequent click chemistry conjugation.
- Alkyne-conjugated benzylguanine
- Enables irreversible and covalent labeling of SNAP fusion proteins
- Provides alkyne functionality for click chemistry conjugation
- White to off-white solid appearance
- For research use only
- Purity of 99.32%
Medchemexpress LLC Azide-PEG4-VC-PAB-doxorubicin | 99.6% | 1222.25 g·mol⁻1 | C57H75N9O21 | 50 MG
Azide-PEG4-VC-PAB-doxorubicin is an antibody-drug conjugate (ADC) agent-linker conjugate that couples the cytotoxic anthracycline doxorubicin to an azide-terminated PEG4-VC-PAB linker for use in bioconjugation and ADC assembly. It is designed for click chemistry conjugation (CuAAC and SPAAC) to alkyne- or DBCO/BCN-containing partners and is supplied as a solid for research use.
Medchemexpress LLC Cholesterol-PEG-biotin | 2000 (average) Da | 25 MG
Cholesterol-PEG-Biotin (MW 2000) is a biotin-conjugated, PEGylated cholesterol lipid designed as a membrane anchor for liposomes and other membrane-mimetic systems. The PEG(2000) spacer increases aqueous solubility and provides steric stabilization, while the terminal biotin enables strong, specific capture by avidin or streptavidin. Supplied as a powder for research use.
Broadpharm Biotin-PEG2-azide | 1910803-72-3 | MFCD26142991 | 500mg
Biotin-PEG2-azide | Putity: 98% | MW: 400.5 | 1910803-72-3 | MFCD26142991 | 500mg
Broadpharm Amino-PEG2-acid | 791028-27-8 | MFCD20926377 | 1g
Amino-PEG2-acid | Putity: 98% | MW: 177.2 | 791028-27-8 | MFCD20926377 | 1g
eMolecules 35164-96-6 | Tos-PEG22-Tos | Broadpharm | MFCD29764344 | 1251.490 | C56H98O26S2 | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 | 500mg | 303671263
Tos-PEG22-Tos | Broadpharm | 35164-96-6 | MFCD29764344 | 1251.490 | C56H98O26S2 | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 | 500mg | 303671263
Medchemexpress LLC DSPE-PEG-Maleimide | 1612754-08-1 | 99.9% | 2000 | 25 MG
DSPE-PEG-Maleimide is a functional lipid component and a thiol-reactive crosslinker. It undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD, making it suitable for research on drug delivery. In vitro, DSPE-PEG-Maleimide successfully conjugates with one thiolated RGD peptide via Michael addition at 4°C, pH 8 to form DSPE-PEG(2000)-RGD.
- Functional lipid component and thiol-reactive crosslinker
- Forms stable thioether bonds via Michael addition with thiol groups
- Applicable for research on drug delivery
- Conjugates with thiolated RGD peptides
Cayman Chemical DMPE-MPEG 2000 100mg
An oligosaccharide comprised of nine a-14-linked glucose molecules has been used as a substrate to study the cleavage distribution and enzyme kinetics of B. licheniformis thermostable a-amylase as well as the enzyme kinetics of A. niger glucoamylase II
Medchemexpress LLC NH-bis(C2-PEG2-NH-Boc) | 2182601-69-8 | 99.9% | 50 MG
NH-bis(C2-PEG2-NH-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to contain two different ligands connected by a linker, allowing for the exploitation of the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs.
- Functions as a PEG-based PROTAC linker.
- Targets PROTAC linkers and PROTAC pathways.
- Applicable in cancer-programmed cell death.
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC Dspe-peg-maleimide, mw 5000 | 99.84% | 500 MG
DSPE-PEG-Maleimide, MW 5000, is a linker lipid composed of DSPE phospholipid and Maleimide. It is utilized in the synthesis of various liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes. It is for research use only.
- Appearance: Solid
- Color: White to off-white
- Molecular weight: 5000 (average)
- Solubility (In vitro): Soluble in DMSO at 50 mg/mL (requires ultrasonic and warming to 60°C; hygroscopic DMSO significantly impacts solubility)
- Functions as a linker lipid in immunoliposome synthesis
- Can be coupled with thiol-p5314-29 peptide
- Sterically stabilized liposomes containing this product can be coupled with thiolated monoclonal antibody OX26 (OX26-SH)
- HELDC liposomes prepared with 3% of this product show stability in particle size over two weeks, maintaining an average diameter of 120 nm
Medchemexpress LLC TCO-NHS Ester (axial) | 1610931-22-0 | C13H17NO5 | 5 MG
TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. It contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
- Click chemistry reagent.
- Can be used as a building block in amine reactions.
- Contains TCO groups for inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine groups.
- Solid appearance.
- White to off-white color.
- Purity of 98.0% or greater.