Non-isotopic Labeling Reagents and Kits
Selleck Chemical LLC NSC697923-10mg
NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A.
Medchemexpress LLC 2-(4-methylphenyl)sulfonyl-5-nitrofuran | 343351-67-7 | MFCD01925132 | 99.9% | C11H9NO5S | 10MG
NSC697923 is a research-grade small-molecule inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) used to block Ubc13-mediated polyubiquitination in biochemical and cellular studies. It is supplied as a white to light-yellow solid with high purity, exhibits good solubility in DMSO, and is stable when stored as a powder at recommended cold temperatures.
- Selective inhibition of UBE2N (Ubc13) activity in vitro and in cells.
- High purity suitable for biochemical and cellular assays.
- White to light-yellow solid with consistent appearance.
- High solubility in DMSO for preparation of concentrated stock solutions.
- Formulation guidance provided for in vivo administration.
- Stable as a powder under recommended cold storage conditions.
Enzo Life Sciences PDGF receptor tyrosine kinase inhibitor (5mg). CAS: 627518-40-5
A cell-permeable compound acting as an ATP-competitive and reversible inhibitor of PDGFR. PDGF receptor tyrosine kinase inhibitor IV displays potent antiproliferative properties in several human tumor cell lines. Alternative name: 3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine, JNJ-10198410. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences VDM-11 (50mg). CAS: 313998-81-1
Selective and potent inhibitor of the anandamide membrane transporter (AMT) (neuronal (C6 glioma cells): IC50=11µM; non-neuronal (rat RBL-2H3 cells): IC50=7.2µM) with negligible action at TRPV1 and weak action at CB1 receptor (CB1: Ki=5µM; CB2: Ki>5µM) and FAAH (IC50=3.7µM/ IC50>50µM (N18TG2 cell membranes). Alternative name: N-Arachidonoyl-4-hydroxy-2-methylaniline, N-(4-Hydroxy-2-methylphenyl)arachidonoylamide. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (1.5mg/ml) or ethanol (1mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences Siguazodan (5mg). CAS: 115344-47-3
A selective phosphodiesterase PDE III inhibitor, IC50=0.7µM. Siguazodan is a potent inotropic, vasodilator and antiplatelet agent with sustained duration of action. It synergizes with PDE IV inhibitors (roliprams) in blocking antigen-induced bronchospasm in the guinea pig. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: Ambient.
Enzo Life Sciences DuP-697 (5mg). CAS: 88149-94-4
DuP-697 is a highly selective and irreversible inhibitor of cyclooxygenase-2 (COX-2). (COX-2 IC50=10nM, COX-1 IC50=800nM). It is an orally effective anti-inflammatory, analgesic and antipyretic agent which is not ulcerogenic. Inhibition of COX-2 by DuP-697 and other inhibitors exacerbates ischemia-induced myocardial dysfunction in the rabbit. It inhibits angiogenesis and induces apoptosis in human endothelial cells. Alternative name: (5-Bromo-2[4-fluorophenyl]-3-[4-methylsulfonyl-phenyl]thiophene). Purity: ≥98% (TLC). Solubility: Soluble in DMSO (10mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: -20°C.
Apexbio Technology LLC High Yield T7 Biotin16 RNA Labeling Kit,25 rxns
High Yield T7 Biotin16 RNA Labeling Kit is designed to generate randomly Biotin16-modified RNA probes by in vitro transcription. Such probes are ideally suited for in situ hybridization and Northern blot hybridization experiments. The principle of labeling is similar to the basic labeling principle of a mixture of Biotin16 RNA labels. Biotin16-UTP is efficiently incorporated into RNA using the optimized reaction buffer and T7 RNA polymerase mixture in place of its natural counterpart UTP. An appropriate Biotin16-UTP substitution typically achieves an optimal balance between reaction and labeling efficiency. However, the individual optimization of the Biotin16-UTP/UTP ratio can be easily achieved using a single nucleotide format. The resulting Biotin-modified RNA probe can then be detected by fluorescence spectroscopy.Other sizes are also available. Please inqury us for quote.
Enzo Life Sciences TG100-115 (10mg). CAS: 677297-51-7
Alternative name: 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences IC87114 (10mg). CAS: 371242-69-2
Alternative name: Phosphatidylinositol 3-kinase p110d inhibitor, PI 3-K inhibitor X. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences mTOR inhibitor WYE-23 (5mg). CAS: 1062169-46-3
Alternative name: 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences mTOR inhibitor WYE-23 (1mg). CAS: 1062169-46-3
Alternative name: 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences WH-4-023 (10mg). CAS: 837422-57-8
Alternative name: 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences AGK7 (SIRT2 inhibitor, inactive control) (5mg). CAS: 304896-21-7
Can be used as an inactive control in experiments with AGK2. Alternative name: SIRT2 Inhibitor (inactive control). Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.