General Cell Based Assays
Eurofins Discoverx cAMP Hunter™ Human ADRA2A Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human ADRA2A Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADRA2A (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
MyBioSource NA/K ATPase
The MyBioSource NA/K ATPase ELISA Kit quantitatively detects NA/K ATPase in various biological samples using a sandwich enzyme immunoassay. It involves binding, washing, and colorimetric detection, with a range of 0.312-20 ng/ml and sensitivity of 0.188 ng/ml.
Abcam Cal-520, AM
Cal-520, AM is a fluorogenic calcium-sensitive dye for detecting intracellular calcium mobilization with significantly improved signal-to-noise ratio and intracellular retention compared to existing calcium indicators.
Eurofins Discoverx PathHunter Human MC5R β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MC5R β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MC5R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical Catlase asy KIt 480Wel
Catalase is an ubiquitous antioxidant enzyme that is present in most aerobic cells. It is involved in the detoxification of H2O2, a ROS that is a toxic product of both normal aerobic metabolism and pathogenic ROS production. Cayman’s Catalase Assay utilizes the peroxidatic function of catalase for determination of enzyme activity. The assay can be used to measure catalase activity in plasma, serum, erythrocyte lysates, tissue homogenates, and cell lysates.
Eurofins Discoverx PathHunter Human NF-kB Pathway Reporter Cell-Based Assay Kit (HEK 293)
The PathHunter NF-kB Pathway Reporter Stable Cell Line Assay (HEK 293) monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR161 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR161 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR161 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OPN5 (Opsin) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human OPN5 (Opsin-5) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure OPN5 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Bioassay Systems EnzyChrom™ NAD/NADH Assay Kit. For sensitive determination of NAD and NADH and evaluation of drug effects on NAD/NADH metabolism.
For sensitive determination of NAD and NADH and evaluation of drug effects on NAD/NADH metabolism. Key Features: Sensitive and accurate. Detection limit of 0.05 µM and linearity up to 10 µM NAD+/NADH in 96-well plate assay. Convenient. The procedure involves adding a single working reagent, and reading the optical density at time zero and 15 min at room temperature. High-throughput. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: OD565nm. Samples: Cell or tissue extracts. Species: All. Procedure: Assay takes 15 min. Kit size: 100 tests. Detection limit: 0.05 µM.
Eurofins Discoverx PathHunter Human AVPR1A Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human AVPR1A Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure AVPR1A (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc AlphaScreen cAMP Detection Kit, 50,000 Assay Points
AlphaScreen cAMP Detection Kit, 50,000 Assay Points
Eurofins Discoverx PathHunter Human BMP-6 (BMPR1B/ACVR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human BMP-6 (BMPR1B/ACVR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of BMPR1B/ACVR2A. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human DDR1 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human DDR1 Stable Cell Line Functional Kinase Assay (U2OS) measures DDR1 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical Cel-Based asy DIgItonIn So 5ea
An OGA inhibitor (IC50 46 nM) selective for OGA overBhexosaminidase (IC50 >10 UM) and a panel of 277 kinases (IC50s >1 UM for all) increases the levels of O-GlcNAcylated proteins in SH-SY5Y cells (EC50 450 nM)
Eurofins Discoverx PathHunter eXpress P2RY1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0941E3CP5M)
The PathHunter P2RY1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ATP) based activation of P2RY1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY1 and EA-tagged β-Arrestin-2. Activation of P2RY1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.