General Cell Based Assays
Cell Signaling Technology TUNEL Assay Kit Fluorescence
TUNEL Assay Kit (Fluorescence, 640 nm) 1 Kit;
Eurofins Discoverx PathHunter Human AVPR2 β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human AVPR2 β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure AVPR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ILEX LIFE SCIENCES LLC QuickZyme Human MMP-7 Activity Assay Kit, 96 Assays, 96-well plate format, immunoassay for active or total matrix metalloproteinase 7 (conditioned culture medium, serum, urine, tissue homogenates samples)
The QuickZyme Human MMP-7 Activity Assay is an enzyme activity immunoassay that enables you to specifically measure both endogenous active MMP-7 and total active MMP-7 (following activation of pro-MMP-7 on the plate with APMA). It can be used for the measurement of MMP-7 activity in various biological samples, such as conditioned culture media, tissue homogenates, serum, plasma and urine. This 96-well plate format assay is based on the QuickZyme technology, using a modified pro-enzyme as a substrate, which upon activation is able to release color from a chromogenic peptide substrate. This multiplication step provides a unique assay sensitivity. ASSAY RANGE: 0.004 ¿ 16 ng/ml. SENSITIVITY: 30 pg/ml (3 h incubation); 4 pg/ml (25 h incubation). SYNONYMS: Matrix metalloproteinase-7, MMP7, Matrilysin, Matrilysin-1, Matrin, Pump-1 protease, Uterine metalloproteinase.
Meso Scale Discovery R-PLEX Rat β-NGF Assay, 5 plate size, Singleplex format, 96-well plate, Plasma and Serum sample types, Dynamic range 0.2 - 6000 pg/mL, LLOD 0.2 pg/mL, For research use only
R-PLEX Rat β-NGF Assay, 5 plate size, Singleplex format, 96-well plate, Plasma and Serum sample types, Dynamic range 0.2 - 6000 pg/mL, LLOD 0.2 pg/mL, For research use only
Indigo Biosciences INDIGO BIOSCIENCES INC Assay, FGFR1c/α-Klotho, Endocrine FGF Signaling, 1x 384-well
This product is an assay for Endocrine FGF Signaling.
- Uses proprietary human cells engineered to provide constitutive expression of Human Fibroblast Growth Factor Receptor 1, isoform 1 and Human Fibroblast Growth Factor Receptor 2, isoform 1.
- Incorporates a luciferase reporter gene functionally linked to tandem NFAT consensus response element sequences.
- Provides an all-inclusive cell-based reporter assay system.
- Includes Reporter Cells, optimized culture medium, heparin-supplemented culture medium, FGF-Acidic (physiological paracrine activator of FGFR1/2), Luciferase Detection Reagents, and a cell culture-ready assay plate.
- Kit materials are sufficient to perform assays in a single 384-well assay plate.
- Cryopreserved mammalian cells are provided and require storage at -80°C until rapid-thaw.
- Intended for research purposes only.
Cayman Chemical AMPK activator, Purity: ≥95%, CAS: 849727-81-7, 5 mg
An indirect activator of AMPK (EC50 = 11.7 μM); stimulates glucose uptake in L6 myocytes and promotes phosphorylation of ACC, a known target of AMPK; decreases blood glucose concentrations in Zucker diabetic rats, demonstrating its utility in whole animals; inhibits the growth of multiple myeloma cells
Meso Scale Discovery R-PLEX AB40 4G8 ASY
The Meso Scale Discovery R-PLEX Human Abeta40 4G8 Assay Kit is a multiplex immunoassay that measures Abeta40 levels in human samples such as serum plasma CSF and cell culture supernatants It uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision The kit includes a plate coated with a 4G8 antibody to capture Abeta40 along with detection antibodies calibrators controls buffers and other reagents needed to run the assay It allows rapid and accurate quantification of Abeta40 levels which may be useful as a biomarker in Alzheimer s disease research and drug development
Medchemexpress LLC Phospholipid transfer protein, recombinant human (HEK293, C-terminal His tag) | >95.0% | 10 UG
Recombinant human phospholipid transfer protein (PLTP) produced in HEK293 cells with a C-terminal 10xHis tag. Supplied lyophilized for biochemical and cell-based functional assays; demonstrates activity in inhibiting LPS-induced TNF-α secretion in macrophage cells.
- Expressed in HEK293 cells.
- C-terminal 10xHis affinity tag.
- Purity greater than 95% by reducing SDS-PAGE.
- Predicted molecular mass 54.4 kDa; appears ~55-90 kDa by SDS-PAGE due to glycosylation.
- Functional activity: 5 μg/mL reduces LPS-induced TNF-α secretion in RAW 264.7 cells.
- Lyophilized formulation with trehalose and mannitol for stability.
- Store frozen; aliquot and keep at -20 °C or -80 °C for long-term storage.
- Available in small research quantities such as 10 μg and 50 μg.
Eurofins Discoverx PathHunter eXpress GPR15 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0682E2CP1L)
The PathHunter GPR15 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR15 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR15 and EA-tagged β-Arrestin-2. Activation of GPR15 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
10X Genomics Inc GEM-X Flex Gene Expression Human n-plex, 64 samples
GEM-X Flex Gene Expression Human n-plex, 64 samples
Carterra SPR Camp - Andover MA CEC
SPR Camp - Andover, MA CEC
Cayman Chemical NonradIoactIve IodID asy K 96
A B2-AR agonist selectively binds to B1- over B2-ARs (Kds 2.9 and 113 nM respectively) as well as B3-adrenergic B2 bradykinin NK1 and NK2 receptors up to 3 M induces cAMP accumulation in cultured human bronchial epithelial cells relaxes guinea pig tracheal strips precontracted with carbamoylcholine ovalbumin or histamine (pD2s 8.4 9.5 and 9.5 respectively) reverses histamine- and ovalbumin-induced bronchoconstriction in guinea pigs (ED50s 1 and 40 nmol/kg respectively)
Eurofins Discoverx PathHunter Human OPRM1 (Opioid mu) β-Arrestin-1 Cell-Based Assay Kit (U2OS)
The PathHunter Human OPRM1 (Opioid mu) β-Arrestin-1 Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure OPRM1 (GPCR) activity via recruitment of β-Arrestin-1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-21 (IL21R/IL2RG) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-21 (IL21R/IL2RG) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL21R/IL2RG. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human TSLP (IL7R/CRLF2) Dimerization Cell-Based Assay Kit (DLD1)
The PathHunter Human TSLP (IL7R/CRLF2) Stable Cell Line Dimerization Assay (DLD1) measures ligand-induced dimerization of IL7R/CRLF2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.