General Cell Based Assays
Cayman Chemical FFA asy Sample Buffer 1ea
A PROTAC that drives Cdk2 degradation selectively degrades Cdk2 (IC50 24 nM) over seven additional CDKs at 500 nM but also degrades Aurora A kinase and IKZF1 at 250 nM reduces Cdk2 levels and increases the percentage of cells expressing CD11b a marker of differentiation in primary AML cells decreases proliferation without reducing the viability of as well as induces differentiation in primary HSCs
GPCR Kinase 3 Expression Kit - BacMam, 10mL - Montana Molecular
GPCR Kinase 3 (GRK3) packaged in BacMam for expression in mammalian cells. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity, enabling rapid assay optimization. Co-express with other Montana Molecular tools includeing GPCRs packaged in BacMam or biosensors for cAMP, DAG, or arrestin signaling.
ABclonal Technology LDH-B
This gene encodes the B subunit of lactate dehydrogenase enzyme which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD in a post-glycolysis process Alternatively spliced transcript variants have been found for this gene Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism and that this isoform is localized in the peroxisomes Mutations in this gene are associated with lactate dehydrogenase B deficiency Pseudogenes have been identified on chromosomes X 5 and 13
