Protein Purification
Genscript Corporation CEACAM-5/CD66e 145-322 His
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
Genscript Corporation CD96/TACTILE C110S His Hum
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells and recent studies suggest both play important inhibitory roles in immune function CD96 has been shown to modulate immune cell activity in mice with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor CD226 offers unique strategies for immuno-oncology drug development
Genscript Corporation Benz-Neburase GMP His-tag
GenScript s offerings are cost-effective with reliable and proven performance for removal of contaminating nucleic acids Furthermore the Benz-Neburase s offerings are produced under stringent quality controls with materials and manufacturing process that are fully traceable allowing for support of IND filing and progression of development stages for various applications
Genscript Corporation MSLN/Mesothelin296-598 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
Genscript Corporation CEACAM-5/CD66e His Cynomolgu
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
eMolecules 133711-99-6 | Medchem Express | Intoplicine (dimesylate) | 5mg | 686240037 | HY-101647A | 540.65 | C23H32N4O7S2
Ambeed | (S)-2-Amino-4-(methylthio)butanamide hydrochloride | 5g | 600848978 | A850839 | 16120-92-6 | 184.680 | C5H13ClN2OS
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Genscript Corporation CD27/TNFRSF7 His Cynomolgus/
CD27 also known as TNFRSF7 is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily It functions as a co stimulatory molecule that supports lymphocyte activation and survival It binds to ligand CD70 and plays a key role in regulating B-cell activation and immunoglobulin synthesis
Genscript Corporation 4-1BB/TNFRSF9Biotin His A
4-1BB is also known as CD137 is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily CD137 can be expressed by activated T cells but to a larger extent on CD8 than on CD4 T cells In addition CD137 expression is found on dendritic cells B cells follicular dendritic cells natural killer cells granulocytes and cells of blood vessel walls at sites of inflammation
![eMolecules 1215387-58-8 | 5-bromo-1H-pyrrolo[2,3-c]pyridine | Pharmablock | MFCD12024306 | 197.035 | C7H5BrN2 | 97.000 | Brc1cc2cc[nH]c2cn1 | 25mg | 551170516](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502517462.JPG-250.jpg)
eMolecules 1215387-58-8 | 5-bromo-1H-pyrrolo[2,3-c]pyridine | Pharmablock | MFCD12024306 | 197.035 | C7H5BrN2 | 97.000 | Brc1cc2cc[nH]c2cn1 | 25mg | 551170516
5-bromo-1H-pyrrolo[2,3-c]pyridine | Pharmablock | 1215387-58-8 | MFCD12024306 | 197.035 | C7H5BrN2 | 97.000 | Brc1cc2cc[nH]c2cn1 | 25mg | 551170516
Genscript Corporation MSLN/Mesothelin487-598 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
Genscript Corporation Fc gamma RI/CD64Biotin His
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains these groups are designated Fc gamma RI (also known as CD64) Fc gamma RII (CD32) and Fc gamma RIII (CD16) Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type