Protein Purification
MilliporeSigma™ Calbiochem™ UbcH13 Inhibitor, NSC697923
The UbcH13 Inhibitor, NSC697923 controls the biological activity of UbcH13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Staurosporine, Streptomyces sp.
Staurosporine, CAS 62996-74-, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinases (IC50 = 7, 20, 1.3, 0.7, & 8.5 nM for PKA, CAMK, MLCK, PKC, & PKG, respectively).
MilliporeSigma™ Calbiochem™ Benztropine
An antagonist of muscarinic M1 and M3 receptors that induces robust differentiation of oligodendrocytes precursor cell differentiation (EC50 = 500nM) and promotes myelination.
MilliporeSigma™ Calbiochem™ Caspase-3 Substrate II, Fluorogenic
Fluorogenic caspase-3 substrate.
MilliporeSigma™ Calbiochem™ Myristoylated-FEEERA, mP6
A cell-permeable myristoylated hexapeptide that selectively inhibits integrin outside-in signaling without affecting inside-out signaling. Blocks the interaction of Gα3 and integrin β3 subunit.
MilliporeSigma™ Calbiochem™ Opn4 Antagonist
Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC50 = 665 nM; using CHO transfectants).
MilliporeSigma™ Calbiochem™ HIF Prolyl Hydroxylase Inhibitor
A cell-permeable, hydroxyquinoline HIF Prolyl Hydroxylase (PHD) inhibitor that displays an IC50 = 2μM in a cell-based assay using a reporter produced by fusing HIF-1α oxygen degradable domain (ODD) to lucifer
MilliporeSigma™ Calbiochem™ Calpain Inhibitor III
The Calpain Inhibitor III, also referenced under CAS 88191-84-8, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Lenaldekar (LDK)
An inhibitor of T cell proliferation (IC50 = 3 μM in CD3+, CD4+, and CD8+ cells). Does not affect other cell types.
MilliporeSigma™ Calbiochem™ MitoBloCK-6
A cell-permeable, stable dichlorosalicylaldehyde Schiff's base that acts as a potent, selective inhibitor of Mia40/Erv1 redox-mediated import pathway (IC50 = 700 nM, 900 nM, an
MilliporeSigma™ Calbiochem™ PP1 Analog III, 3-MB-PP1
PP1 Analog III, 3-MB-PP1 primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ VEGF Inhibitor, V1
The VEGF Inhibitor, V1 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ L-165,041
A cell-permeable phenoxyacetic acid derivative that acts as a potent and selective peroxisome proliferator activator receptor δ (PPARδ) agonist (Ki = 6 nM for hPPARδ and 730 nM for hPPARγ).
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor I, Dynasore
The Dynamin Inhibitor I, Dynasore, also referenced under CAS 304448-55-3, controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ FtsZ Polymer Stabilizer, PC190723
A benzamide ether derivative that exhibits potent bactericidal activity against Staphylococcus aureus and Bacillus subtilis (minimum inhibitory concentration = 0.5 to 1mg/ml), but does not affect