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Equivalent to Sigma P8849, for use in purification of Histidine-tagged proteins to increase protein stability. Other sizes are available. Please inqury us for quote.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Equivalent to Sigma P8215, for use with fungal and yeast extracts to increase protein stability. Other sizes are available. Please inqury us for quote.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Equivalent to Sigma P8215, for use with fungal and yeast extracts to increase protein stability. Other sizes are available. Please inqury us for quote.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
DNAX accessory molecule-1 (DNAM-1) also known as CD226 is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily DNAM-1 mediates cellular adhesion to other cells bearing its ligands CD112 and CD155 and cross-linking DNAM-1 with antibodies causes cellular activation Furthermore DNAM-1 can interact with PVR and PVRL2
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Deoxyribonuclease I (DNase I) is DNA-specific endonuclease that cleaves both single-stranded DNA double-stranded DNA and DNA-RNA hybrids yielding 5 -phosphate-terminated polynucleotides with a free hydroxyl group on position 3 producing tetranucleotides The activity of DNase I is strictly dependent on Ca2 and can be activated by divalent metal ions such as Mg2 or Mn2 In the presence of Mg2 DNase I nonspecifically recognizes and cleaves a double-stranded DNA at anysite on either strand and in the presence of Mn2 it recognizes and cleaves almost the same sites on both strands of the DNA to produce DNA fragments with blunt ends or sticky ends with 1 2 nucleotide overhangs GenScript is offering DNase I produced by expression in a P pastoris strain carrying a plasmid encoding the bovine DNase I
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4-1BB is also known as CD137 is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily CD137 can be expressed by activated T cells but to a larger extent on CD8 than on CD4 T cells In addition CD137 expression is found on dendritic cells B cells follicular dendritic cells natural killer cells granulocytes and cells of blood vessel walls at sites of inflammation
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Active Motif's miRNA Target IP Kit was designed to identify the physical interactions of a miRNA with endogenous mRNA transcripts. It utilizes protein G-coupled magnetic beads and a pan-Ago antibody to efficiently immunoprecipitate miRNA/mRNA complexes that have associated with Ago1, Ago2 or Ago3 proteins as part of a RISC complex. Following their immunoprecipitation, the mRNA targets are purified and then amplified by qRT-PCR using gene-specific primers. This makes it possible to validate the specific mRNA transcripts that are binding targets of that miRNA. It is also possible to profile the immunoprecipitated mRNA molecules using conventional expression microarrays or RNA-Seq.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Cell permeable caspase inhibitor I - 1mg , Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-CHO Category/Application: Caspase Inhibitor This item is non returnable
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Trop-2 also known as epithelial glycoprotein-1 antigen (EGP-1) is a protein that in humans is encoded by the TACSTD2 gene Mutations of this gene result in gelatinous drop-like corneal dystrophy an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness
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GITR-RFP-NFkB-Gluc is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a RFP fluorescent reporter under the control of pathway responsive elements and includes a antibiotic selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
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The EasySep™ Human CD3 Positive Selection Kit II is designed to isolate CD3+ cells from fresh or previously frozen peripheral blood mononuclear cells by positive selection. Desired cells are targeted with Tetrameric Antibody Complexes recognizing CD3 and dextran-coated magnetic particles. The cocktail also contains an antibody to human Fc receptor to minimize nonspecific binding. Labeled cells are separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off. The CD3 antigen is expressed on all T cells and CD56+ NKT cells.This product replaces the EasySep™ Human CD3 Positive Selection Kit (Catalog #18051) for even faster cell isolations.
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