Protein Purification
Cayman Chemical h-e5NT InhIbItr 5C 10mg
An inhibitor of ecto-5'-nucleotidase (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively); inhibits ENPP1, ENPP3, and TNAP (IC50s = 1.12, 1.37, and 1.48 µM, respectively, for the human enzymes)
Medchemexpress LLC Araloside VII (Congmunoside VII) | 340982-22-1 | MFCD22124709 | 99.9% | 1121.26 g/mol | C54H88O24 | 10 MG
Araloside VII is a naturally occurring saponin isolated from leaves of Aralias elate, supplied for research use. It is provided as a solid, white to yellow powder with a molecular formula of C54H88O24, molecular weight ≈1121.26 g/mol, and CAS number 340982-22-1. Store protected from light at 4°C; in solution, store at -80°C for long-term (up to 6 months) or -20°C for short-term (about 1 month).
- natural saponin isolated from Aralias elate leaves.
- high purity (≈99.9%) for research applications.
- molecular weight ≈1121.26 g/mol; formula C54H88O24.
- provided as a 10 mg solid suitable for small-scale experiments.
- store protected from light at 4°C; use cold solvent storage for extended stability.
- intended for laboratory research use only; not for human or diagnostic use.
Abcam SAHA (Vorinostat), HDAC inhibitor, 50MG
MW 264.32 Da, Purity >98%. Potent non-selective HDAC inhibitor (IC₅₀ values are 10 and 20 nM for HDAC1 and HDAC3, respectively). Induces apoptosis and shows antiproliferative effects against cancer cell lines (IC₅₀ = 3 - 8 μM). Antitumor effects in vivo. No effect on class III HDACs. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PQ 401, Cell-permeable IGF1R inhibitor, 10MG
MW 341.8 Da, Purity >99%. Cell-permeable IGF1R inhibitor (IC₅₀ = 12 μM for IGF-stimulated autophosphorylation). Shows antiproliferative effects against MCF-7 breast cancer cells. Induces renal hypertrophy in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam WHI-P131 hydrochloride, JAK3 inhibitor, 10MG
MW 297.31 Da, Purity >98%. Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC₅₀ values of 9.1 μM and 78 μM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical nutrophIl Elasts InhIbItr 25mg
An N-benzoylindazole derivative that selectively targets the binding domain of neutrophil elastase (IC50 = 7 nM)
Abcam Histone Demethylase KDM1/LSD1 Inhibitor Assay Kit.
Histone Demethylase KDM1/LSD1 Inhibitor Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Gabe x ate mesylate, General serine protease inhibitor, 10MG
MW 417.5 Da, Purity >99%. General serine protease inhibitor (Ki values are 3.4 nM, 5, 1.8 μM and 2.6 mM at tryptase, thrombin, tyrpsin and kallikrein serine proteases respectively). Additionally inhibits nitric oxide synthase. Displays antithrombotic activity and antitumor effect. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Epirubicin HCl 25mg 56390-09-1 4'-epidoxorubicin HCl
Epirubicin HCl (4'-epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical mP-9mP-13 InhIbItr I 1mg
A cell-permeable inhibitor of MMPs that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both); less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC50s = 43, 23, and 920 nM, respectively)
Cayman Chemical Src KInase InhIbItr I 1mg
A potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes; also inhibits RIP-2
Cayman Chemical JAK2 InhIbItr V 10mg
A selective inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 µM; blocks the proliferation of erythroleukemia cells and human hematopoietic progenitor cells expressing JAK2-V617F
Cayman Chemical GlutamInase C InhIbItr 11 5mg
An inhibitor of GAC; inhibits GAC enzyme activity (EC50 = 10.64 nM); reduces the viability of A549 NSCLC cells (IC50 = 4.025 nM); reduces colony formation by, and intracellular glutamate levels in, A549 cells at 0.1 and 1 µM; reduces tumor growth in an A549 mouse xenograft model at 100 mg/kg
Cayman Chemical USP7-USP47 InhIbItr 5mg
A dual inhibitor of USP7 and USP47 (IC50s = 0.42 and 1 μM, respectively); selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC50s = >31.6 μM); inhibits the growth of HCT116 cells (EC50 = 7.6 μM)