Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ SNC80
A very potent and selective δ opioid receptor agonist (IC50
MilliporeSigma™ Calbiochem™ Necrosis Inhibitor, IM-54
The Necrosis Inhibitor, IM-54, also referenced under CAS 861891-50-1, selectively blocks oxidative stress-induced necrotic cell death. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Latrunculin A, Latrunculia magnifica
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
MilliporeSigma™ Calbiochem™ MAS 7
A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan.
MilliporeSigma™ Calbiochem™ Luciferase Inhibitor II
The Luciferase Inhibitor II, also referenced under CAS 10205-56-8, controls the biological activity of Luciferase.
MilliporeSigma™ Calbiochem™ NFAT Activation Inhibitor III
The NFAT Activation Inhibitor III, also referenced under CAS 3519-82-2, controls the biological activity of NFAT. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ 4-Hydroxyphenylretinamide
A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity.
MilliporeSigma™ Calbiochem™ TMEM16A Inhibitor, T16Ainh-A01
The TMEM16A Inhibitor, T16Ainh-A01 controls the biological activity of TMEM16A.
MilliporeSigma™ Calbiochem™ AG 538
A potent, cell-premeable, reversible, and competitive inhibitor of IGF-1 receptor kinase (IC50 = 400 nM).
MilliporeSigma™ Calbiochem™ Nα-Benzyloxycarbonyl-L-lysine Thiobenzyl Ester, Hydrochloride
Highly sensitive substrate for trypsin-like enzymes and granule-associated serine esterase.
MilliporeSigma™ Calbiochem™ Shikonin
A naphthoquinone found in the Chinese herb Shiunko.
MilliporeSigma™ Calbiochem™ InSolution™ Purmorphamine
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
MilliporeSigma™ Calbiochem™ CA-074 Me
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
MilliporeSigma™ Calbiochem™ Thrombin Receptor Agonist
The Thrombin Receptor Agonist, also referenced under CAS 137339-65-2, controls the biological activity of Thrombin Receptor. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ ATIC Dimerization Inhibitor
A cell-permeable dipeptide that reversibly blocks the homodimerization of aminoimidazole carboxamide ribonucleotide transformylase/inosine nomophosphate cyclohydrolase (ATIC) and inhibits its activity (Ki = 691 nM, Kd = 2